Results 241 to 250 of about 175,639 (315)

Comparison of 5-Fluorouracil/Leucovorin and Capecitabine as Adjuvant Therapies in Biliary Tract Cancer. [PDF]

J Gastroenterol Hepatol
Lee TS, Choi YH, Kim JY, Lee MH, Paik KH, Cho IR, Kwon WI, Lee SH, Lee IS, Lee MA, Jang JY, Ryu JK, Kim YT, Paik WH.   +13 more
europepmc   +1 more source

Efficacy and Safety Assessment of 5‐Fluorouracil, Irinotecan and Oxaliplatin‐Loaded Implants in Mouse and Pig Models for Pancreatic Cancer Therapy

Advanced Materials, Volume 38, Issue 26, 8 May 2026.
A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade, Ashna A. Kumar, Samuel O. Nitschke, Paul Joyce, Elahe Minaei, Stephanie E. Reuter, Chelsea Penney, Holly Warren, Ruby Shepherd, Jeremy N. Dinoro, Gordon G. Wallace, Anthony Dosseto, Sameera Ansar, Naila Islam, Alistair Lochhead, George Sharbeen, Phoebe A. Phillips, Morteza Aghmesheh, Wayne J. Hawthorne, Kara L. Vine‐Perrow   +19 more
wiley   +1 more source

N-benzylbenzamide derivative (SBM685) as a novel MDR1 inhibitor for overcoming 5 fluorouracil resistance in gastric cancer through computational and in vitro analysis. [PDF]

Discov Oncol
Al Fayi M, Dera AA.
europepmc   +1 more source

Radiotherapy Enhancement by Gold Nanocluster‐functionalized Nanoliposomes Using Polychromatic Orthovoltage X‐ray Irradiation

Advanced Materials Interfaces, Volume 13, Issue 9, 5 May 2026.
Lipid drug carriers to which ultra‐small gold nanoparticles were added enabled more efficient radiotherapy of cultured pancreatic cancer tumors. These nanoparticles boosted radiation‐induced damage to tumors by generating more reactive molecules, though higher gold levels are needed for strong benefits.
Nazareth Milagros Carigga Gutierrez, Eaazhisai Kandiah, Sofia Leo, Erwan Dupont, Fabrizio Johnson‐Corrales, Marc‐André Hograindleur, Sarvenaz Keshmiri, Hélène Elleaume, Benoit Busser, Romain Haudecoeur, Véronique Jacob, Anthony Vella, Véronique Josserand, Maxime Henry, Jean‐Luc Coll, Amandine Hurbin, Xavier Le Guével, Mans Broekgaarden   +17 more
wiley   +1 more source

5-Fluorouracil-Induced Acute Toxic Leukoencephalopathy: A Rare Adverse Effect and Its Early Detection on MRI. [PDF]

Cureus
Ambreen A, Naveed MA, Javed K, Naeem MQ, Chaudhry N.   +4 more
europepmc   +1 more source

GSDME-mediated pyroptosis is essential for the chemotherapeutic effects achieved by combined treatment of temsirolimus and 5-fluorouracil in ovarian carcinoma cells. [PDF]

Am J Transl Res
Chen Z, Ye M, Gu C, Wen N, Wang N, Meng Y.   +5 more
europepmc   +1 more source

Fibrillarin Contributes to the Oncogenic Characteristics of Colorectal Cancer Cells and Reduces Sensitivity to 5-Fluorouracil. [PDF]

Cancers (Basel)
Wu T, Chalabi-Dchar M, Xiong W, Arnould L, Aimontche E, Beaumel S, Dumontet C, Marcel V, Fenouil T, Diaz JJ, Albaret MA, Mertani HC.   +11 more
europepmc   +1 more source

Correction: Chemoresistance mechanisms to 5-Fluorouracil and reversal strategies in lung and breast cancer. [PDF]

Sci Rep
Zhong C, Wang S, Jiang WJ, Li Z, Wang X, Fan S, Huang J, Wu HJ, Sheng R, Fei T.   +9 more
europepmc   +1 more source

Investigating adsorption of 5-fluorouracil and 6-mercaptopurine on icosahedral silver nanoparticles through DFT and TDDFT. [PDF]

Sci Rep
Morad R.
europepmc   +1 more source