Results 191 to 200 of about 11,853,684 (309)

Impact of RAS/RAF Mutations on Metastatic Treatment Response Following Total Neoadjuvant Therapy in Patients With Stage IV Rectal Cancer

Asia-Pacific Journal of Clinical Oncology, EarlyView.
There is limited understanding of the impact of underlying RAS/RAF mutational status on total neoadjuvant therapy metastatic tumor response rates in curative Stage IV rectal cancer patients. Complete metastatic tumor response to TNT was demonstrated in half as many mRAS as wtRAS patients and disease progression was higher in patients harboring RAS ...
Tracy R. Fitzsimmons, Z. Bunjo, E. L. Neo, A. Badiei, M. Penniment, S. Selva‐Nayagam, A. Ruszkiewicz, J. Wong, T. Sammour   +8 more
wiley   +1 more source

Correction: Olaparib-mediated enhancement of 5-fluorouracil cytotoxicity in mismatch repair deficient colorectal cancer cells. [PDF]

BMC Cancer
de Castro E Gloria H, Nogueira LJ, Grudzinski PB, da Costa Ghignatti PV, Guecheva TN, Leguisamo NM, Saffi J.   +6 more
europepmc   +1 more source

Nimotuzumab Combined With Chemoradiotherapy in Head and Neck Squamous Cell Carcinoma and Nasopharyngeal Carcinoma: A Systematic Review and Meta‐Analysis

Asia-Pacific Journal of Clinical Oncology, EarlyView.
This meta‐analysis of 18 studies (3962 patients) demonstrates that nimotuzumab combined with chemoradiotherapy significantly improves overall survival and progression‐free survival in locally advanced head and neck squamous cell carcinoma, without increasing severe toxicity.
Chengzheng Bao, Yue Zhang, Xiang Fei, Kaifeng Ji, Ming Jia, Zhijun Li, Chao Bian   +6 more
wiley   +1 more source

Phosphate-Surface-Modified Silica Nanoparticles for 5-Fluorouracil as a Prolonged Drug Delivery System. [PDF]

Pharmaceuticals (Basel)
Lis A, Surażyński A, Koźmiński P, Szymański P.   +3 more
europepmc   +1 more source

Updated EAACI Statement on Drug Hypersensitivity Skin Testing: Methodology and Non‐Irritative Concentrations

Allergy, EarlyView.
ABSTRACT These updated EAACI guidelines aim to standardize skin testing methodologies for both immediate and non‐immediate drug hypersensitivity reactions. For immediate reactions, the optimal testing window is 4–6 weeks post‐reaction; whereas beyond 6 months, false‐negative results increase.
Annick Barbaud, Lene Heise Garvey, Elizabeth Phillips, Michael Ardern‐Jones, Sevim Bavbek, Patrizia Bonadonna, Jean‐Christoph Caubet, Ana‐Maria Copaescu, Valentina Gueli, Jose Julio Laguna, Ricardo Madrigal‐Burgaleta, Francesca Mori, Vito Sabato, Maria J Torres, Knut Brockow   +14 more
wiley   +1 more source

Thymoquinone and pentoxifylline modulate 5-fluorouracil-induced senescence and apoptosis in colorectal cancer spheroids. [PDF]

Res Pharm Sci
Makalani F, Ghanbari A, Tabandeh MR, Nasta TZ, Souq AJ, Jalili C.   +5 more
europepmc   +1 more source

Roux‐en‐Y Reconstruction After Esophagectomy for Postoperative Functional Complaints: A Case Series

ANZ Journal of Surgery, EarlyView.
Functional complaints affect half of esophagectomy patients, with no standard treatment. In nine patients, Roux‐en‐Y reconstruction for obstruction, redundant conduit, and weight loss was safely performed, with one major complication and no Grade 4 out of five events. Complete symptom resolution reached 67% at 3 months and 89% at 1 year.
Donika Zogaj, Stefan H. E. M. Clermonts, Frederieke A. Dijkstra, Boudewijn van Etten, Roy J. J. Verhage, Jenneke T. H. Hamminga, Jan Willem Haveman   +6 more
wiley   +1 more source

Neoadjuvant Docetaxel/Cisplatin/5-Fluorouracil Enabling Laryngeal Preservation in Cervical Esophageal Carcinosarcoma: A Case Report. [PDF]

Surg Case Rep
Mizusawa Y, Kunitomo T, Takeda Y, Matsumoto H, Hashimoto M, Maeda N, Tanabe S, Ayada Y, Noma K.   +8 more
europepmc   +1 more source

Outcomes and Trends of Anal Squamous Cell Carcinoma in Queensland: A 26‐Year Review

ANZ Journal of Surgery, EarlyView.
Anal squamous cell carcinoma incidence and mortality increased substantially in Queensland over 26 years, while survival outcomes remained unchanged. Evolving HPV prevention and screening strategies offer opportunities to reduce future disease burden, but substantial implementation barriers exist.
Amanda G. Liesegang, Joseph C. Kong, Nicholas Lutton, Glen R. Guerra   +3 more
wiley   +1 more source

Real-time LC-OCT monitoring of scalp hypertrophic actinic keratosis clearance following cryotherapy, laser, and 5-fluorouracil therapy. [PDF]

Front Med (Lausanne)
Bortone G, Coppolelli V, Gargano L, Svara F, Boostani M, Nisticò SP, Pellacani G, Cantisani C.   +7 more
europepmc   +1 more source