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Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2014
IntroductionDietary serotonin increases urinary secretion of 5-HIAA. A falsely elevated 5-HIAA may lead to incorrect suspicion of a neuroendocrine tumour. Therefore, we determined the effect and duration of dietary serotonin on serum 5-HIAA concentration.
Hamalainen Esa +9 more
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IntroductionDietary serotonin increases urinary secretion of 5-HIAA. A falsely elevated 5-HIAA may lead to incorrect suspicion of a neuroendocrine tumour. Therefore, we determined the effect and duration of dietary serotonin on serum 5-HIAA concentration.
Hamalainen Esa +9 more
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Urinary 5-HIAA Unrelated to Cystic Fibrosis
Chest, 19941994;106;1309 Chest Charles C. Roberts Craig A. Friesen, Martin L. Bauer, William Shaw, V. Fred Burry and Urinary 5-HIAA Unrelated to Cystic Fibrosis http://chestjournal.chestpubs.org/content/106/4/1309.2.citation services can be found online on the World Wide Web at: The online version of this article, along with updated information and ISSN:0012-3692
Craig A. Friesen +4 more
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Altered CSF 5-HIAA Disposition in Pathologic Male Gamblers
CNS Spectrums, 1999AbstractPrevious reports concerning the cerebrospinal fluid (CSF) of pathologic gamblers have described disturbed norepinephrine and dopamine (but not serotonin) functioning in the central nervous system. We analyzed neurotransmitter metabolites in two consecutive 6-mL samples of CSF obtained from 10 pathologic male gamblers punctured at the L4-5 level
C, Nordin, T, Eklundh
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5-HIAA in Cerebrospinal Fluid and Deficit Schizophrenic Characteristics
British Journal of Psychiatry, 1990Higher CSF 5-HIAA concentrations and lower CSF HVA concentrations have been associated with various measures of slowed motor behaviour and communication in schizophrenic patients. To derive a single, reliable measure of deficit characteristics in schizophrenic patients, we entered four items of the BPRS reflecting negative symptoms, a work history ...
J G, Csernansky +5 more
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CSF 5‐HIAA Predicts Suicide Risk After Attempted Suicide
Suicide and Life-Threatening Behavior, 1994Suicide risk after attempted suicide, as predicted by cerebrospinal fluid (CSF) monoamine metabolite concentrations, was studied in a sample of 92 psychiatric mood disorder inpatients admitted shortly after attempting suicide. The potential of the serotonin metabolite 5‐hydroxyindoleacetic acid (5‐HIAA) in the CSF to predict suicide risk within the ...
P, Nordström +6 more
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[5-HIAA: perspectives in nephrology].
Comptes rendus des seances de la Societe de biologie et de ses filiales, 19895-Hydroxyindoleacetic acid (5-HIAA) is the chief end-product of serotonin metabolism. The gastrointestinal tract is the main source of urinary 5-HIAA. The rest originates from the degradation of brain or platelet serotonin stores. Main abnormalities in 5-HIAA excretion have been observed in carcinoid tumors (elevation) or hyperphenylalaninemia ...
J L, Elghozi, D, Laude
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Intraspinal Pressure Influences CSF Disposition of Tryptophan and 5-HIAA
Neuropsychobiology, 2001Cerebrospinal fluid (CSF) concentrations of monoamine compounds are influenced by factors such as age, gender, height, body weight, tapping time, and atmospheric pressure. We have now examined the role of intraspinal pressure. Thirteen male volunteers underwent lumbar puncture in the right decubitus position without preceding strict bed rest.
T, Eklundh, C, Nordin
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Developmental Brain Research, 1985
Sprague-Dawley rat pups were deprived of food and/or the dam in experiment 1 for 24 h prior to sacrifice at 4, 10, 16 and 22 days postnatally and analysis of 5-HT, 5-HIAA and 5-HIAA/5-HT ratios in cortex, forebrain minus cortex, and brainstem. Deprivation was observed to increase indoles and their ratio early in life, with the most pronounced effects ...
L P, Spear, F M, Scalzo
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Sprague-Dawley rat pups were deprived of food and/or the dam in experiment 1 for 24 h prior to sacrifice at 4, 10, 16 and 22 days postnatally and analysis of 5-HT, 5-HIAA and 5-HIAA/5-HT ratios in cortex, forebrain minus cortex, and brainstem. Deprivation was observed to increase indoles and their ratio early in life, with the most pronounced effects ...
L P, Spear, F M, Scalzo
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CSF 5-HIAA, cortisol and DHEAS levels in suicide attempters
European Neuropsychopharmacology, 2013The serotonin system and the hypothalamic-pituitary-adrenal (HPA) axis are involved in the biological vulnerability to suicidal behaviour. Altered levels of dehydroepiandrosterone (DHEA) and its sulphate ester DHEAS have been reported in neuropsychiatric conditions.
Andreas, Chatzittofis +5 more
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Cholesterol, CSF 5-HIAA, violence and intent in suicidal men
Psychiatry Research, 2010Associations between suicide, violent behaviour and both hypocholesterolaemia and low 5-hydroxyindolacetic acid (5-HIAA) in the cerebrospinal fluid (CSF) have been suggested. The relationships between lipids, the serotonergic system, suicidal and aggressive behaviors are complex.
Jussi, Jokinen +2 more
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