Serum 5-Hydroxyindoleacetic Acid and Ratio of 5-Hydroxyindoleacetic Acid to Serotonin as Metabolomics Indicators for Acute Oxidative Stress and Inflammation in Vancomycin-Associated Acute Kidney Injury [PDF]
Antioxidants, 2021 The incidence of vancomycin-associated acute kidney injury (VAKI) varies from 5–43%, and early detection of VAKI is important in deciding whether to discontinue nephrotoxic agents.
Hyun-Seung Lee +4 more
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Surgical Correction of Carcinoid Heart Disease Improves Liver Function and 5-Hydroxyindoleacetic Acid Levels [PDF]
Frontiers in Surgery, 2022 IntroductionCarcinoid heart disease (CHD) is a consequence of neuroendocrine tumors releasing 5-hydroxytryptamine (5-HT) into the systemic circulation, affecting right heart valves, causing fibrosis, and eventually right heart failure.
Husnain Abbas Shah +13 more
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Updated Parkinson's disease motor subtypes classification and correlation to cerebrospinal homovanillic acid and 5-hydroxyindoleacetic acid levels [PDF]
Clinical Parkinsonism & Related Disorders, 2023 Introduction: Motor classifications of Parkinson's Disease (PD) have been widely used. This paper aims to update a subtype classification using the MDS-UPDRS-III and determine if cerebrospinal neurotransmitter profiles (HVA and 5-HIAA) differ between ...
Christopher Adams +6 more
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Impact of Plasma 5 Hydroxyindoleacetic Acid, a Serotonin Metabolite, on Clinical Severity in Acute Respiratory Distress Syndrome [PDF]
Frontiers in Medicine, 2021 Acute respiratory distress syndrome (ARDS) is characterized by dysregulated vascular permeability. The clinical outcomes remain poor, and the disease burden is widespread.
Takeshi Tanaka +5 more
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Serum and plasma 5-hydroxyindoleacetic acid as an alternative to 24-h urine 5-hydroxyindoleacetic acid measurement [PDF]
Annals of Clinical Biochemistry, 2016 Background Neuroendocrine tumours are slow growing tumours known to secrete a variety of vasoactive peptides which give rise to symptoms of the carcinoid syndrome. The diagnosis and monitoring of patients with neuroendocrine tumours is undertaken in many centres using 24 h urinary measurement of 5 ...
Brian Keevil +2 more
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5-Hydroxyindoleacetic acid as a biomarker for revealing perforation in acute appendicitis [PDF]
BMC GastroenterologyBackground The present study investigated the level of 5-hydroxyindoleacetic acid (5-HIAA) in perforated and nonperforated appendicitis patients. This issue is important for timely diagnosis of acute appendicitis complications and making decision about ...
Arash Mohammadi Tofigh +6 more
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Decreased homovanillic acid and 5‐hydroxyindoleacetic acid levels in the cerebrospinal fluid of patients with Dravet syndrome with parkinsonism [PDF]
Epilepsia OpenDravet syndrome (DS) is an early onset, developmental, and epileptic encephalopathy characterized by drug‐resistant seizures and multiple comorbidities.
Ryo Sugiyama +5 more
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The effect of dietary tryptophan supplementation, and an oral tryptophan challenge, on urinary excretion of 5-hydroxyindoleacetic acid in domestic dogs [PDF]
Frontiers in Veterinary ScienceChronic enteropathies, commonly referred to as inflammatory bowel disease, are multi-factorial disorders that affect a substantial proportion of both the human population and companion animals.
Chloe Cheung +3 more
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Risk factors for suicide among patients with schizophrenia: a cohort study focused on cerebrospinal fluid levels of homovanillic acid and 5-hydroxyindoleacetic acid [PDF]
Neuropsychiatric Disease and Treatment, 2016 Daniel Neider, Leif H Lindström, Robert Bodén Department of Neuroscience, Psychiatry, Uppsala University, Uppsala University Hospital, Uppsala, Sweden Background: The objective of this study was to investigate the association ...
Neider D, Lindström L, Boden R
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5-Hydroxyindoleacetic acid, a new ligand for GPR35, plays an important role in inflammatory disease [PDF]
Acta Biochimica et Biophysica Sinica, 2022 Yang Zhisheng +3 more
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