Results 21 to 30 of about 2,522,863 (212)

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease. [PDF]

open access: yesAnn Clin Transl Neurol
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Shao JY   +7 more
europepmc   +2 more sources

Metabolites of Tryptophane and Phenylalanine as Markers of Small Bowel Ischemia-Reperfusion Injury

open access: yesOpen Chemistry, 2018
Ischemic-reperfusion injury of the small intestine is an acute clinical condition with high mortality rate. This study describes the changes in levels of phenylalanine and tryptophan metabolites in intestinal homogenates and urine samples of Wistar male ...
Mašlanková Jana   +9 more
doaj   +1 more source

Kynurenine pathway in post-mortem prefrontal cortex and cerebellum in schizophrenia: relationship with monoamines and symptomatology

open access: yesJournal of Neuroinflammation, 2021
Background The cortico-cerebellar-thalamic-cortical circuit has been implicated in the emergence of psychotic symptoms in schizophrenia (SZ). The kynurenine pathway (KP) has been linked to alterations in glutamatergic and monoaminergic neurotransmission ...
Amira Ben Afia   +8 more
doaj   +1 more source

Difference and Similarity of Serotonin and Pteridines to Act on Lipid Metabolism

open access: yesPteridines, 1998
Incorporation of fatty acids into phospholipids has been investigated using samples of rat liver homogenate, Krebs-Ringer phosphate buffer (pH=7.4) containing 0.3% albumin, fatty acid mixture and glycerol.
Rudzite Vera   +5 more
doaj   +1 more source

Lesch-Nyhan Syndrome

open access: yesPediatric Neurology Briefs, 1988
Five boys with Lesch-Nyhan syndrome and varying degrees of dystonia, chorea, spasticity, ataxia, dysarthria, and mental retardation were studied at the Depts of Neurology and Medicine, Baylor College of Medicine, and Depts of Neurology and Pediatrics ...
J Gordon Millichap
doaj   +1 more source

Plasma 5-hydroxyindoleacetic acid as an endogenous index of renal plasma flow [PDF]

open access: yes, 1989
Plasma 5-hydroxyindoleacetic acid as an endogenous index of renal plasma flow. 5-Hydroxyindoleacetic acid (5-HIAA), the major serotonin metabolite, was measured in human plasma and urine using liquid chromatography and electrochemical detection.
Elghozi, Jean-Luc   +9 more
core   +1 more source

Thirty-Second Net Stressor Task in Adult Zebrafish

open access: yesBio-Protocol, 2015
Zebrafish have become a popular animal model for behavioral neuroscience (Gerlai, 2014). Recent studies have demonstrated that brief experimental handling prior to euthanizing animals can subsequently alter biological measures quantified post-mortem (e.g.
Steven Tran, Robert Gerlai
doaj   +1 more source

Blood, urine and cerebrospinal fluid analysis in TH and AADC deficiency and the effect of treatment

open access: yesMolecular Genetics and Metabolism Reports, 2021
Background: Aromatic L-amino acid decarboxylase (AADC) deficiency and tyrosine hydroxylase (TH) deficiency are rare inherited disorders of monoamine neurotransmitter synthesis which are typically diagnosed using cerebrospinal fluid examination of ...
Tessa Wassenberg   +5 more
doaj   +1 more source

Neurotransmitter evaluation in the hippocampus of rats after intracerebral injection of TsTX scorpion toxin

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2009
TsTX is an α-type sodium channel toxin that stimulates the discharge of neurotransmitters from neurons. In the present study we investigated which neurotransmitters are released in the hippocampus after TsTX injection and if they are responsible for
ALA Nencioni   +5 more
doaj   +1 more source

Simultaneous measurement of serotonin and 5-hydroxyindoleacetic acid in rat brain using a liquid chromatographic method with electrochemical detection

open access: yes, 1991
A simple and sensitive method for the simultaneous measurement of 5-hydroxytryptamine and its main metabolite 5-hydroxyindoleacetic acid in rat brain is described.
Odink, J., Vries, M. de
core   +2 more sources

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