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Ibogalogs induce antiseizure activity in rodents by a mechanism involving 5-HT<sub>2A/2C</sub> receptor activation with a major role of 5-HT<sub>2A</sub> receptors in the hippocampal CA3 subfield. [PDF]

open access: yesBiochem Pharmacol
Chagraoui A   +11 more
europepmc   +1 more source

Pharmacologic MRI Brain Imaging Studies of Serotonin 5-HT<sub>1</sub> Receptor Agonists in Awake Mice. [PDF]

open access: yesPharmacol Res Perspect
Brems BM   +5 more
europepmc   +1 more source
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Regulation of 5-HT Release in the CNS by Presynaptic 5-HT Autoreceptors and by 5-HT Heteroreceptors

2000
The amount of serotonin (5-hydroxytryptamine; 5-HT) released from the varicosities of the serotoninergic axon terminals in response to invading action potentials at a given frequency is by no means constant. As generally accepted now, exocytotic release of 5-HT can be significantly modified by presynaptic receptors, i.e.
M. Göthert, E. Schlicker
openaire   +1 more source

5-HT and alcohol abuse

Trends in Pharmacological Sciences, 1992
Recent experimental data, both in animals and the clinic, suggest that drugs selectively interacting with the 5-HT system may reduce alcohol intake. Although the precise mechanisms underlying these drug effects are unknown, it seems that there are at least two pharmacological strategies available, described in this review by Edward Sellers and ...
Sellers, Edward M.   +2 more
openaire   +3 more sources

5-HT

British Journal of Pharmacology, 2006
S P H Alexander, A Mathie, J A Peters
  +5 more sources

5-HT system and cognition

Neuroscience & Biobehavioral Reviews, 1999
The study of 5-hydroxytryptamine (5-HT) system has benefited from the identification, classification and cloning of multiple 5-HT receptors (5-HT1 to 5-HT7). Growing evidence suggests that 5-HT is important in learning and memory and all its receptors might be implicated in this.
openaire   +2 more sources

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