Platelet count and sleep quality in immune thrombocytopenia: correlation with 5-hydroxytryptamine and therapeutic implications of platelet-5-HT-melatonin axis dysregulation. [PDF]
Jiao Y +5 more
europepmc +1 more source
Enhancing Small Molecule Sensing With Aptameric Functionalized Nano Devices
Unveiling an ultra‐sensitive, non‐invasive neurotransmitter sensor. For the first time, a nanoscale sensor for detecting an important neurotransmitter was demonstrated using micro‐electromechanical systems (MEMS) technology. Our approach utilized field‐effect transistor (FET)‐based readout to enable pico‐molar detection of biomarkers in sweat.
Thi Thanh Ha Nguyen +11 more
wiley +1 more source
Targeting 5-HT Is a Potential Therapeutic Strategy for Neurodegenerative Diseases. [PDF]
Xing C +5 more
europepmc +1 more source
A soft robotic simulator is developed to replicate the digital removal of feces (DRF), a sensitive yet essential nursing procedure. Integrating soft actuators, sensors, and a realistic rectal model, the simulator balances functional fidelity with perceptual realism. Engineering evaluations and nurse feedback confirm its potential to enhance training in
Shoko Miyagawa +10 more
wiley +1 more source
Immune stress impairs broiler performance by affecting hypothalamic methylation modification and intestinal 5-HT synthesis. [PDF]
Huang B +6 more
europepmc +1 more source
From Rigid to Soft Robotic Approaches for Neuroendoscopy
Robotic assistance has had minimal impact on deep intraventricular surgeries, where small‐scale, precision, and reduced invasiveness can contribute to improved patient outcomes. Emerging technologies in rigid, soft, and hybrid robotics are reviewed to identify the most promising mechanisms for deep brain navigation in addition to an attempt to identify
Kieran Gilday +3 more
wiley +1 more source
The value of 5-HT, leptin, and NE in the classification of premature ejaculation. [PDF]
Chen Z, Zhang X.
europepmc +1 more source
Ectodermal tissue excised from Xenopus embryos self‐organizes into a three‐dimensional mucociliary organoid. Here, we generate a neural variant, termed neurobot, by implanting neural precursor cells. Neurobots develop mature neurons, adopt distinct morphologies, exhibit more complex motility, and respond differentially to neuroactive compounds. Imaging
Haleh Fotowat +6 more
wiley +1 more source
Electroacupuncture Exerts Anti-Obesity Effects by Affecting the Gut Microbiota and Upregulating Acetic Acid and 5-HT Levels in Obese Rats. [PDF]
Zhang J +9 more
europepmc +1 more source
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang +16 more
wiley +1 more source

