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Higher-End Serotonin Receptors: 5-HT5, 5-HT6, and 5-HT7
Journal of Medicinal Chemistry, 2003AbstractFor Abstract see ChemInform Abstract in Full Text.
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Modern 5-HT receptor classification and 5-HT based drugs
Expert Opinion on Investigational Drugs, 1994Based on operational (agonist and antagonist rank order), transductional (second messenger coupling) and structural (gene and amino acid sequence) criteria, the Nomenclature Committee of the Serotonin Club has discerned four distinct 5-HT receptor types, besides two less well characterised categories including some recombinant and the so-called ‘orphan’
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Desensitization of Terminal 5-HT Autoreceptors by 5-HT Reuptake Blockers
Archives of General Psychiatry, 1991To the Editor.— We commend Goodman et al 1 for their rigorous study on the effectiveness of fluvoxamine in obsessive-compulsive disorder (OCD) and for the comprehensive and scholarly review on the possible mechanisms of action of 5-hydroxytryptamine (5-HT) reuptake blockers in OCD.
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4-Aminoethylpiperazinyl aryl ketones with 5-HT₁A/5-HT₇ selectivity.
Bioorganic & medicinal chemistry, 2012The well-known 5-HT(1A)/5-HT(7) selectivity issue was tackled by a new series of 4-aminoethylpiperazinyl aryl ketones (1a-1l) specifically designed to distinguish the two hydrophobic sites centered at the anchoring salt bridge. The 4-aminoethylpiperazinyl aryl ketones showed a wide spectrum of activity and selectivity for the 5-HT receptors depending ...
Mi Kyoung, Kim +6 more
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Interactions between the 5-HT Transporter and 5-HT Receptors.
A53. VASCULAR SMOOTH MUSCLE CELLS, 2009W Ren, BL Fanburg
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5-HT: on the psychiatrist's couch
Trends in Pharmacological Sciences, 1992M, Briley, D, Grahame-Smith
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