Results 111 to 120 of about 25,240 (222)
Specificity of 5‐HT2A Receptor Ligands in Mice
The FASEB Journal, 2008 In‐Vitro studies of RNA editing of the serotonin type 2C receptor (5‐HT2CR) have shown a pronounced loss of function in the fully edited isoform (VGV). Our goal is to evaluate functional coupling of the edited 5‐HT2CR in‐vivo using transgenic mice that solely express the VGV isoform.
Uade Olaghere da Silva +1 more
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Hallucinogens: mechanisms and medical complications [PDF]
, 2013 Thesis (M.A.)--Boston UniversityHallucinogens are drugs that alter consciousness by distorting primarily auditory and visual perception but they can affect any sensory system. Hallucinogens also affect judgment, orientation, memory, or emotion.
Chan, Ryan Harry Alexander
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Experience-dependent serotonergic signaling in glia regulates targeted synapse elimination.
PLoS BiologyThe optimization of brain circuit connectivity based on initial environmental input occurs during critical periods characterized by sensory experience-dependent, temporally restricted, and transiently reversible synapse elimination.
Vanessa Kay Miller, Kendal Broadie
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Recreational use, analysis and toxicity of tryptamines [PDF]
, 2015 The definition New psychoactive substances (NPS) refers to emerging drugs whose chemical structures are similar to other psychoactive compounds but not identical, representing a "legal" alternative to internationally controlled drugs.
Mannocchi, Giulio +3 more
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Unraveling monoamine receptors involved in the action of typical and atypical antipsychotics on glutamatergic and serotonergic transmission in prefrontal cortex [PDF]
, 2013 El pdf del artículo es la versión post-print.The systemic administration of noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonists has been considered as a pharmacological model of schizophrenia.
Adell, Albert +2 more
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Role OF 5-HT2C receptors in dyskinesia [PDF]
, 2016 By integrating knowledge gained by pharmacogenetic, neuroanatomical and pharmacological studies, a model can be constructed how serotonin (5-HT) affects the vulnerability to induce tardive dyskinesia.
Ivanova, Svetlana A. +1 more
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PLoS ONE, 2015 Bacopa monnieri has been used in Ayurvedic medicine to improve memory and cognition. The active constituent responsible for its pharmacological effects is bacoside A, a mixture of dammarane-type triterpenoid saponins containing sugar chains linked to a ...
Seetha Ramasamy +5 more
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Dual role of endogenous serotonin in 2,4,6-trinitrobenzene sulfonic acid-induced colitis
Frontiers in Pharmacology, 2016 Background and Aims: Changes in gut serotonin content have been described in Inflammatory Bowel Disease and in different experimental models of colitis: the critical role of this monoamine in the pathogenesis of chronic gastrointestinal inflammation is ...
Alberto eRapalli +7 more
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Laminar and Cellular Distribution of Monoamine Receptors in Rat Medial Prefrontal Cortex
Frontiers in Neuroanatomy, 2017 The prefrontal cortex (PFC) is deeply involved in higher brain functions, many of which are altered in psychiatric conditions. The PFC exerts a top-down control of most cortical and subcortical areas through descending pathways and is densely innervated ...
Noemí Santana +4 more
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Serotonin 5‐HT2A receptor activity mediates adipocyte differentiation
The FASEB Journal, 2009 Serotonin 5‐HT2 receptors are expressed in variety of tissues and play important roles in many processes. The 5‐HT2A receptor is primary known for its role in CNS function. This receptor is, however, expressed in many peripheral tissues where its role remains largely unknown. Here, we present data demonstrating
Bangning Yu, Charles D Nichols
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