Results 101 to 110 of about 25,240 (222)

Unraveling Persistent Genital Arousal Disorder—A Case Report on Innovative Therapeutic Approaches

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Persistent genital arousal disorder (PGAD) is a rare and distressing condition characterized by persistent, unwanted genital arousal in the absence of sexual desire, often leading to significant psychological distress and functional impairment.
Abdullah Hassan   +6 more
wiley   +1 more source

Central 5-HT2A receptors modulate the vagal bradycardia in response to activation of the von Bezold-Jarisch reflex in anesthetized rats

open access: yesBrazilian Journal of Medical and Biological Research, 2011
Activation of 5-hydroxytryptamine (5-HT) 5-HT1A, 5-HT2C, 5-HT3, and 5-HT7 receptors modulates the excitability of cardiac vagal motoneurones, but the precise role of 5-HT2A/2B receptors in these phenomena is unclear.
H.A. Futuro Neto   +4 more
doaj   +2 more sources

5-HT2A Receptor Binding in the Frontal Cortex of Parkinson’s Disease Patients and Alpha-Synuclein Overexpressing Mice: A Postmortem Study

open access: yesParkinson's Disease, 2016
The 5-HT2A receptor is highly involved in aspects of cognition and executive function and seen to be affected in neurodegenerative diseases like Alzheimer’s disease and related to the disease pathology. Even though Parkinson’s disease (PD) is primarily a
Nadja Bredo Rasmussen   +8 more
doaj   +1 more source

Serotonin reuptake inhibitors and cardiovascular disease [PDF]

open access: yes, 2005
Selective serotonin re-uptake inhibiting drugs (SSRIs) are widely used for endogenous depression. In addition to depleting the nerve terminals of serotonin they also lower blood platelet serotonin levels.
Belcher, P.R.   +2 more
core   +1 more source

Functional brain imaging : a brief overview of imaging techniques and their use in human and canine anxiety research [PDF]

open access: yes, 2011
When used in combination with specific radioactive markers, functional imaging modalities such as Single Photon Emission Computed Tomography (SPECT) and Positron Emission Tomography (PET) enable the visualization of several neurotransmitter receptors and
Audenaert, Kurt   +6 more
core  

5-HT2a receptor in mPFC influences context-guided reconsolidation of object memory in perirhinal cortex [PDF]

open access: yes, 2018
Context-dependent memories may guide adaptive behavior relaying in previous experience while updating stored information through reconsolidation. Retrieval can be triggered by partial and shared cues.
Bekinschtein, Pedro Alejandro   +5 more
core   +1 more source

In Vitro and In Vivo Characterization of PCC0104005, a Novel Modulator of Serotonin-Dopamine Activity, as an Atypical Antipsychotic Drug

open access: yesScientific Reports, 2018
PCC0104005 is a novel drug candidate for treating schizophrenia that displays high affinity for serotonin, dopamine, and noradrenaline receptors, including partial agonism at dopamine D2, D3, D4, serotonin 5-HT1A, and 5-HT2A receptors and antagonism at 5-
Yanan Xu   +5 more
doaj   +1 more source

Focal Spot, Fall/Winter 2001 [PDF]

open access: yes, 2001
https://digitalcommons.wustl.edu/focal_spot_archives/1089/thumbnail ...

core   +1 more source

Understanding vulnerability for depression from a cognitive neuroscience perspective: a reappraisal of attentional factors and a new conceptual framework [PDF]

open access: yes, 2010
We propose a framework to understand increases in vulnerability for depression after recurrent episodes that links attention processes and schema activation to negative mood states, by integrating cognitive and neurobiological findings.
De Raedt, Rudi, Koster, Ernst
core   +1 more source

Solid-Phase Synthesis of Arylpiperazine Derivatives and Implementation of the Distributed Drug Discovery (D3) Project in the Search for CNS Agents [PDF]

open access: yes, 2011
We have successfully implemented the concept of Distributed Drug Discovery (D3) in the search for CNS agents. Herein, we demonstrate, for the first time, student engagement from different sites around the globe in the development of new biologically ...
Bojarski, Andrzej J.   +11 more
core   +4 more sources

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