Results 191 to 200 of about 125,938 (267)

GlycoChat Uncovers Glycan–Lectin Circuits in the Tumor Microenvironment of Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
Aberrant glycosylation drives cancer progression, yet its role in the tumor microenvironment remains unclear. We developed GlycoChat to map glycan–lectin circuits at single‐cell resolution. We discovered that cancer cells induce immunosuppressive macrophage differentiation and impair phagocytosis through interactions with CLEC10A and SIGLEC3 ...
Dinh Xuan Tuan Anh   +8 more
wiley   +1 more source

Mast cell-5-HT-HTR2A axis involvement in chronic itch induced by SADBE. [PDF]

open access: yesMol Pain
Fan L   +9 more
europepmc   +1 more source

Magnetically Responsive Piezoelectric Nanocapacitors Enhance Neural Recovery Following Spinal Cord Injury via Targeted Spinal Magnetic Stimulation

open access: yesAdvanced Science, EarlyView.
This study presents a novel “in vivo–in vitro” therapeutic strategy for spinal cord injury by leveraging magnetically responsive piezoelectric nanomaterials. These nanomaterials enable targeted delivery of localized electrical stimulation at the injury site through noninvasive external magnetic actuation, thereby promoting axonal regeneration and ...
Zhihang Xiao   +9 more
wiley   +1 more source

AI‐Directed 3D Printing of Hierarchical Polyurethane Foams

open access: yesAdvanced Science, EarlyView.
Digitally guided direct ink writing, combined with AI‐generated design, enables the fabrication of hierarchical polyurethane foams with tunable multiscale porosity. This approach produces architected foams featuring interconnected open‐cell networks and tailored mechanical properties, advancing the development of adaptive, high‐performance materials ...
Dhanush Patil   +15 more
wiley   +1 more source

A Blood‐Brain Barrier‐Penetrant Ag(III) Corrole Compound Rescues Alzheimer's Disease Pathology by Targeting Aβ42‐Induced Oxidative Stress

open access: yesAdvanced Science, EarlyView.
The newly designed metallo‐corrole (Mor‐Cor)Ag(III) with a morpholino group exhibited promising therapeutic potential for Alzheimer's disease. It significantly reduces reactive oxygen species (ROS), decreases GFAP expression, increases neurite length, and decreases cell death compared to other similar metallo‐corroles. Abstract Alzheimer's disease (AD)
Arup Tarai   +7 more
wiley   +1 more source

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