Results 71 to 80 of about 9,970,544 (261)

We Put the "Fast" in Breakfast and the "Fun" Back into the Ball

open access: yes, 2000
The 500 Festival Breakfast at the Brickyard was formerly known as the Mayors Breakfast. In 1984, the Mayors Breakfast served as the official opening of the Hoosier Dome with 5,000 guests attending. Today, the event continues to honor Indiana mayors while
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Homozygous INV(-500-C1) E17.5

open access: yes, 2018
Homozygous inversion of the genomic region INV(-500-C1) analyzed at embryonic day E17.
Kazunori Sunadome (5396135)   +25 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

A Tribute to Reflect and Honor

open access: yes, 2000
For over 50 years, the 500 Festival has recognized the true meaning of Memorial Day by kicking off the weekend with the 500 Festival Memorial Service. This solemn service pays tribute to those Indiana men and women who made the ultimate sacrifice for our
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Research on Field-of-View Reconstruction Technology of Specific Bands for Spatial Integral Field Spectrographs

open access: yesPhotonics
Integral field technology, as an advanced spectroscopic imaging technique, can be used to acquire the spatial and spectral information of the target area simultaneously.
Jie Song   +3 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

A Mini Splendored Thing

open access: yes, 1979
This 13.1 mile running event started with 800 participants in 1977. Today, the Mini-Marathon has become a vital part of Indianapolis’ civic fabric. Since 1987, the “Mini” has been the nation’s largest half-marathon now with more than 35,000 participants.
500 Festival
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Effect of selected catechins on doxorubicin antiproliferative efficacy and hepatotoxicity in vitro

open access: yesActa Pharmaceutica, 2014
Catechins may influence both desirable and undesirable effects of many drugs. In this study, the in vitro effect of (+)-catechin, (-)-epicatechin, (-)-epigallocatechin, (-)-epicatechin gallate, and (-)-epigallocatechin gallate (EGCG) on the efficacy of ...
Rudolfová Petra   +5 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

A Tradition Like No Other

open access: yes, 2000
Each year hundreds of thousands of people from around the world embrace the magical month of May in Indianapolis. The 500 Festival’s annual calendar of events and programs connect the community in large proportions and showcase the city of Indianapolis ...
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