Results 61 to 70 of about 9,896,464 (337)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Protection 500 (P 500) çeliğinin kuru-kayma aşınma davranışı
Bartın University International Journal of Natural and Applied SciencesBu çalışmada, Protection 500 (P 500) çeliğinin iki farklı kayma hızında (4 ve 8 mm/s) ve üç farklı yük (10, 20 ve 30 N) altında kuru-kayma aşınma davranışı incelenmiştir. Deneyler ball-on-disk aşınma aparatında ileri-geri hareket modunda gerçekleştirilmiştir. Aşındırıcı olarak 6 mm çapında WC bilya kullanılmıştır.
Yılmaz Küçük, Mustafa Gök
openaire +2 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
A Deriva e Suas Pistas Dentro de um Processo de Criação Cênica Pelo Mar de Ruas e Praças
Pitágoras 500, 2016 Este artigo relata as experiências da Trupé de Teatro em processo colaborativo de criação cênica pelas ruas e praças do Centro da cidade de Sorocaba. Buscamos, aqui, pistas sobre a Deriva, o estado de Deriva - procedimento utilizado pelo grupo durante a ...
Carlos Alberto Doles Junior +1 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
O besteirol dos 500 Anos - em poucas palavras
Convergência Lusíada, 2001 Levando-se em conta nossa pitoresca realidade, até que a quantidade de besteiras dita e escrita sobre o controvertido aniversário do Brasil não dá para surpreender.
João Ubaldo Ribeiro
doaj
Pitágoras 500, 2019 Neste artigo, analisaremos os métodos de trabalho e os espetáculos selecionados do diretor polonês Tadeusz Kantor e do diretor brasileiro Antunes Filho.
Argus Cecil Nery Monteiro
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source