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520 CTSA Search Solutions

Journal of Clinical and Translational Science, 2022
OBJECTIVES/GOALS: CTSA Search Solutions (https://ctsa-search.rutgers.edu/search/) is a database that allows users to systematically conduct structured searches among the 60+ CTSA hub websites for information related to NCATS goals and CTSA hub activities.
Barbara Tafuto, Riddhi Vyas, Trish Pruis
doaj   +1 more source

مدى التزام مراقبي الحسابات العراقيين بإجراءات المراجعة التحليلية في عملية التدقيق وفق معيار المراجعة الدولي 520

مجلة الغري للعلوم الاقتصادية والادارية, 2022
يهدف البحث للتعرف على مدى التزام مراقبي الحسابات في مكاتب التدقيق (قطاع خاص) ، ومراقبي الحسابات في ديوان الرقابة المالية الإتحادي ( قطاع عام ) بمعيار التدقيق الدولي (520) ، وكذلك التعرف على مدى التزام مراقبي الحسابات بالإجراءات التحليلية في جميع مراحل ...
محمد حسن خضير , سارة راجي ناجي الزبيدي   +1 more
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NVL-520 Is a Selective, TRK-Sparing, and Brain-Penetrant Inhibitor of ROS1 Fusions and Secondary Resistance Mutations

Cancer Discovery, 2022
NVL-520, a selective macrocyclic inhibitor of ROS1, demonstrated antitumor activity in patient case studies of ROS1 inhibitor–refractory lung cancers without observed neurologic toxicities attributed to TRK inhibition.
A. Drilon, J. Horan, A. Tangpeerachaikul, B. Besse, S. Ou, S. Gadgeel, D. Camidge, A. van der Wekken, Linh Nguyen-Phuong, Adam Acker, Clare Keddy, K. Nicholson, S. Yoda, S. Mente, Yuting Sun, J. Soglia, N. Kohl, J. Porter, M. Shair, V. Zhu, M. Davare, A. Hata, H. Pelish, Jessica J. Lin   +23 more
semanticscholar   +1 more source

RNA Interference Therapy With ARC‐520 Results in Prolonged Hepatitis B Surface Antigen Response in Patients With Chronic Hepatitis B Infection

Hepatology, 2020
ARC‐520, the first an RNA interference (RNAi) therapeutic, was designed to reduce all RNA transcripts derived from covalently closed circular DNA, leading to a reduction in viral antigens and hepatitis B virus (HBV) DNA.
M. Yuen, I. Schiefke, Jung‐Hwan Yoon, S. Ahn, J. Heo, Ju ng-Hyun Kim, H. Chan, K. Yoon, H. Klinker, M. Manns, J. Petersen, T. Schluep, J. Hamilton, B. Given, C. Ferrari, Ching‐lung Lai, S. Locarnini, R. Gish   +17 more
semanticscholar   +1 more source

Propofol, an Anesthetic Agent, Inhibits HCN Channels through the Allosteric Modulation of the cAMP-Dependent Gating Mechanism

Biomolecules, 2022
Propofol is a broadly used intravenous anesthetic agent that can cause cardiovascular effects, including bradycardia and asystole. A possible mechanism for these effects is slowing cardiac pacemaker activity due to inhibition of the hyperpolarization ...
Morihiro Shimizu, Xinya Mi, Futoshi Toyoda, Akiko Kojima, Wei-Guang Ding, Yutaka Fukushima, Mariko Omatsu-Kanbe, Hirotoshi Kitagawa, Hiroshi Matsuura   +8 more
doaj   +1 more source

Descending Necrotizing Mediastinitis Caused by Streptococcus pyogenes in a Child with Primary Epstein–Barr Virus Infection

Pediatric Reports, 2022
Descending necrotizing mediastinitis (DNM) is a severe, life-threatening disease with a high mortality rate resulting from sepsis or other complications.
Miki Yoshimura, Tomoo Daifu, Minoru Suehiro, Tsuyoshi Shoji, Yoshihisa Higuchi   +4 more
doaj   +1 more source

Advanced Technologies for Stabilization and High Performance of Seawater RO Membrane Desalination Plants

Membranes, 2021
Seawater desalination plants that use reverse osmosis (RO) membranes have become a core part of social infrastructure, and should be designed to meet the needs of product water quality and production capacity, while considering various environmental ...
Hiroo Takabatake, Masahide Taniguchi, Masaru Kurihara   +2 more
doaj   +1 more source

Determination of Proper Application Timing and Frequency for Management of Tomato Leaf Mold Disease by Commercially Available Microbial Preparations

Research in Plant Disease, 2011
In order to develop a environmentally friendly control protocol for managing tomato leaf mold disease in the field, we employed bacteria- and fungi-based commercially available microbial preparations. The field experiment was conducted from April to July
Beom Ryong Kang, Sug-Ju Ko, Do-Ik Kim, Duck-Soo Choi , Seon-Gon Kim   +4 more
doaj   +1 more source

Localization of Thioredoxin-Interacting Protein in Aging and Alzheimer’s Disease Brains

NeuroSci, 2022
Thioredoxin-Interacting Protein (TXNIP) has been shown to have significant pathogenic roles in many human diseases, particularly those associated with diabetes and hyperglycemia. Its main mode of action is to sequester thioredoxins, resulting in enhanced
Haruka Tsubaki, Anarmaa Mendsaikhan, Undral Buyandelger, Ikuo Tooyama, Douglas G. Walker   +4 more
doaj   +1 more source

100 m/500 Mbps underwater optical wireless communication using an NRZ-OOK modulated 520 nm laser diode.

Optics Express, 2019
In this paper, we proposed and experimentally demonstrated a long-distance high-speed underwater optical wireless communication (UOWC) system in a laboratory environment by using a low-cost green laser diode (LD) and power-efficient non-return-to-zero on-
Jiemei Wang, Chunhui Lu, Shangbin Li, Zhengyuan Xu   +3 more
semanticscholar   +1 more source