Results 31 to 40 of about 1,737,981 (331)

Improved Manufacturability and In Vivo Comparative Pharmacokinetics of Dapagliflozin Cocrystals in Beagle Dogs and Human Volunteers

Pharmaceutics, 2021
Dapagliflozin (DAP), which improves glycemic control in patients with type 2 diabetes mellitus, has poor physical properties against heat and moisture, thus hindering its manufacturing potential.
Sangho Cho, Jeongwook Lee, Yongwon Yoo, Minyong Cho, Seil Sohn, Beom-Jin Lee   +5 more
doaj   +1 more source

Atypically Shaped Cardiomyocytes (ACMs): The Identification, Characterization and New Insights into a Subpopulation of Cardiomyocytes

Biomolecules, 2022
In the adult mammalian heart, no data have yet shown the existence of cardiomyocyte-differentiable stem cells that can be used to practically repair the injured myocardium.
Mariko Omatsu-Kanbe, Ryo Fukunaga, Xinya Mi, Hiroshi Matsuura   +3 more
doaj   +1 more source

The Community Initiative LEADER I and the implementation and results of the Hungarian Pilot LEADER programme in rural development

Bulletin of Geography. Socio-Economic Series, 2013
The aim of this study is to present the basic methodological elements of the LEADER Community Initiative in rural development established in 1991 and its practical implementation in geography.
RuszkaiCDFMR Csaba, KovácsCDFMR Tibor
doaj   +1 more source

Phenol degradation using 20, 300 and 520 kHz ultrasonic reactors with hydrogen peroxide, ozone and zero valent metals [PDF]

, 2009
The extent of phenol degradation by the advanced oxidation process in the presence of zero valent iron (ZVI) and zero valent copper (ZVC) was studied using 20, 300 and 520 kHz ultrasonic (US) reactors.
Bremner, David H., Chand, Rashmi, Gogate, Parag R., Ince, Nilsun H.   +3 more
core   +3 more sources

Current Overview of Osteogenesis Imperfecta

Medicina, 2021
Osteogenesis imperfecta (OI), or brittle bone disease, is a heterogeneous disorder characterised by bone fragility, multiple fractures, bone deformity, and short stature.
Mari Deguchi, Shunichiro Tsuji, Daisuke Katsura, Kyoko Kasahara, Fuminori Kimura, Takashi Murakami   +5 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Optimizing the colour and fabric of targets for the control of the tsetse fly Glossina fuscipes fuscipes [PDF]

, 2012
Background: Most cases of human African trypanosomiasis (HAT) start with a bite from one of the subspecies of Glossina fuscipes. Tsetse use a range of olfactory and visual stimuli to locate their hosts and this response can be exploited to lure tsetse ...
CH Green, CH Green, CH Green, CH Green, CH Green, CH Green, CH Green, CH Green, D Steverding, DJ Rogers, G Gibson, GA Vale, GA Vale, GA Vale, Glyn A. Vale, HI Hossain, HL Needles, HM Rowland, J Esterhuizen, Jenny M. Lindh, JM Lindh, LD Galloway, MI Mwangelwa, Mike J. Lehane, MM Mohamed-Ahmed, N Troje, Parikshit Goswami, PP Simarro, PP Simarro, PP Simarro, R Brun, R Hardie, RC Hardie, RDC Team, RG Fargher, Rhoel Ramos Dinglasan, Richard S. Blackburn, RS Blackburn, S Mihok, S Mihok, S Torr, Sarah E. J. Arnold, SJ Torr, SJ Torr, Steve J. Torr   +44 more
core   +8 more sources

The Value of Interleukin-6 among Several Inflammatory Markers as a Predictor of Respiratory Failure in COVID-19 Patients

Diagnostics, 2021
Patients with coronavirus disease 2019 (COVID-19) develop severe respiratory failure within a short period during the clinical course. It is essential to predict respiratory deterioration in the short term. We investigated the use of inflammatory markers
Mitsuhiro Fujino, Michiyo Ishii, Takuya Taniguchi, Hiroya Chiba, Masaki Kimata, Masahito Hitosugi   +5 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Book Review [PDF]

, 1992
Reviews of the following books: K. S. SHRADER-FRECHETTE, Risk AND RATIONALITY (U. California Press 1991) [312 pp.] Index of Names, Index of Subjects, Notes. CIP 91-3294; ISBN 0-520-07287-1 (Cloth $39.95); ISBN 0-520-07289-8 (Pbk. $15.95). [2120 Berkeley
Gibbons, Hugh H.
core   +1 more source