Results 1 to 10 of about 1,527,120 (330)

miR-543 regulates high glucose-induced fibrosis and autophagy in diabetic nephropathy by targeting TSPAN8

BMC Nephrology, 2022
Background Diabetic nephropathy (DN) is one of the most common and serious complications of diabetes, which can lead to renal failure and fatality. miRNAs are an important class of endogenous non-coding RNAs implicated in a wide range of biological ...
Langen Zhuang, Xiaoxu Ge, Xiaolei Hu, Qingqing Yang, Xiaoyan Pei, Guoxi Jin   +5 more
doaj   +2 more sources

circRNA THBS1 silencing inhibits the malignant biological behavior of cervical cancer cells via the regulation of miR-543/HMGB2 axis

Open Medicine, 2023
Circular RNA (circRNA) THBS1 has been shown to exist as an oncogene in non-small-cell lung cancer, but its role in cervical cancer is still unclear. Our experiment aimed to uncover the functions and specific mechanism of circRNA THBS1 in cervical cancer ...
Tian Rui, Li Huixin, Ren Songjie, Li Shukui, Fang Run, Liu Yang   +5 more
doaj   +2 more sources

Exosomal miR-543 Inhibits the Proliferation of Ovarian Cancer by Targeting IGF2

Journal of Immunology Research, 2022
Objective. Ovarian cancer (OvCa) is the most lethal gynaecological malignancy worldwide. We aimed to illustrate the potential function and molecular mechanism of exosomal microRNA-543 (miR-543) in the oncogenesis and development of OvCa.
Shupei Zhang, Diling Pan, Shaoyu Zhang, Qiumei Wu, Lan Zhen, Shihuang Liu, Jingjing Chen, Rong Lin, Qiuhua Hong, Xiangqin Zheng, Huan Yi   +10 more
doaj   +2 more sources

Circ_0002984 promotes proliferation, migration and inflammatory cytokine secretion and inhibits apoptosis of rheumatoid arthritis fibroblast-like synoviocytes by inducing PCSK6 through miR-543

Journal of Orthopaedic Surgery and Research, 2023
Background Rheumatoid arthritis (RA) is inflammatory arthritic disease, and circular RNA is involved in RA development. The aim of the present work is to analyze the role of circ_0002984 in the process of RA fibroblast-like synoviocytes (RAFLSs) and the ...
Jian-zuo Lu, Jie Yang, Sheng-tuo Zhou, Kai-luo Xie   +3 more
doaj   +2 more sources

Knockdown of long non-coding RNA PVT1 induces apoptosis of fibroblast-like synoviocytes through modulating miR-543-dependent SCUBE2 in rheumatoid arthritis

Journal of Orthopaedic Surgery and Research, 2020
Background Rheumatoid arthritis (RA), a kind of autoimmune disorder, is featured by many physical symptoms and proliferation of fibroblast-like synoviocytes (FLSs). The relevance of long non-coding RNAs (lncRNAs) in the progression of RA has been probed.
Junxia Wang, Xianghui Kong, Haijian Hu, Shunfang Shi   +3 more
doaj   +2 more sources

MiR-543 promotes tumorigenesis and angiogenesis in non-small cell lung cancer via modulating metastasis associated protein 1

Molecular Medicine, 2020
Objective This study is aimed to explore the role of miR-543 in non-small cell lung cancer (NSCLC), and verify whether miR-543 targets metastasis associated protein 1 (MTA1) to affect tumorigenesis and angiogenesis in NSCLC.
Dawei Wang, Li Cai, Xudong Tian, Wenjun Li   +3 more
doaj   +2 more sources

Relationship between the degree of Helicobacter pylori infection and miR-155 and miR-543 expression levels in gastric cancer [PDF]

BMC Gastroenterology
Background To analyze the relationship between Helicobacter pylori (HP) infection degree and miR-155 and miR-543 expression levels in gastric cancer (GC).
Ziwei Wang, Xinxin Zhou, Mosang Yu, Xin Hu   +3 more
doaj   +2 more sources

Recording the direct surgeon’s view with an operating microscopic view improves microscopic ophthalmic surgery training [PDF]

International Journal of Ophthalmology, 2023
AIM: To establish a recording system with a direct view of the surgeon to supplement video recording under an operating microscope, which lacks information on the movement and position of the surgeon's hands, and to facilitate the reproduction of a ...
Masayuki Akimoto, Kosei Tomita, Miyo Yoshida, Yuki Hama   +3 more
doaj   +1 more source

Maintaining Essential Nutrition Services to Underfive Children in Yemen: A Programmatic Adaptation Amidst the COVID-19 Pandemic

Children, 2021
The World Health Organization (WHO) acknowledged that, as health services divert their attention to the COVID-19 pandemic, the delivery of essential nutrition services may be compromised.
Ferima Coulibaly-Zerbo, Ayoub Al-Jawaldeh, Zita C. Weise Prinzo, Marina Adrianopoli, Eshrak Naji Mohammed Al-Falahi, Shafekah Alahnoumy, Nosheen Mohsan Usman, Fanda Ahmed Moqbel, Latifah Abbas Ali, Mohammed Shroh, Ensegam Mohammed Al-Sakkaf, Abdulrazzaq Musaed, Maison Al-Sakkaf, Mohammed Dahnan, Fahim Al-Hakimi, Doa Kutbi Omer, Moatsim Hael, Lara Nasreddine   +17 more
doaj   +1 more source

Clinical Validation of Fetal cfDNA Analysis Using Rolling-Circle-Replication and Imaging Technology in Osaka (CRITO Study)

Diagnostics, 2021
Background: Noninvasive prenatal genetic testing (NIPT) has been adopted as the first choice for aneuploidy screening. The purposes of this study were to investigate the accuracy of Vanadis® NIPT (hereafter CRITO-NIPT) in order to gain a deeper insight ...
Ritsuko Kimata Pooh, Chika Masuda, Risa Matsushika, Megumi Machida, Takako Nakamura, Masayoshi Takeda, Hiroyasu Ohashi, Mami Kumagai, Kohtaro Uenishi, Fredrik Roos, Fredrik Persson, Osamu Shimokawa   +11 more
doaj   +1 more source