Results 31 to 40 of about 250,662 (244)
Intradural disk herniation (IDH) is a rare condition, occurring more often at the L4-5 level. We examined a case of an IDH at the L1-2 level mimicking an intradural spinal tumor. A 71-year-old woman with a long history of backache and pain radiating down
Daisuke Tateiwa +6 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The main objective of this work was to study the physicochemical and catalytic properties of bimetallic supported catalysts [1%M-Fe/Al2O3-Cr2O3 (2:1) (M = Ru, Au, Pt, Pd)] in Fischer-Tropsch synthesis.
Paweł Mierczyński +6 more
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Delayed Spontaneous Bleeding in the Blind Eye of a Type A Hemophilic Patient
A 40-year-old man was complaining of severe left ocular pain and headache for the past 2 months. His left eye was traumatized and rendered blind about 20 years ago.
Gi Sung Son, Sang Un Lee, Sung Chul Kim
doaj +1 more source
Background/Aims: MicroRNAs (miRNAs, miRs) have emerged as important post-transcriptional regulators in various cancers. miR-543 has been reported to play critical roles in hepatocellular carcinoma and colorectal cancer, however, the role of miR-543 in ...
Yang Du +5 more
doaj +1 more source
MicroRNA-543 in systemic diseases and possible applications in gynecologic tumors
In recent years, an increasing number of young women have been diagnosed with cancer, including some nulliparous women. Therefore, many young patients with early-stage cancer desire to preserve fertility after cytotoxic oncological treatments.
Yan-Ran Sheng +5 more
doaj +1 more source

