Results 61 to 70 of about 250,662 (244)

gln+1 ALGEBRA OF MATRIX DIFFERENTIAL OPERATORS AND MATRIX QUASI-EXACTLY-SOLVABLE PROBLEMS

open access: yesActa Polytechnica, 2013
The generators of the algebra gln+1 in the form of differential operators of the first order acting on Rn with matrix coefficients are explicitly written.
Yuri F. Smirnov, Alexander Turbiner
doaj   +1 more source

Synthesis and Biological Evaluation of BODIPY-PF-543 [PDF]

open access: yes, 2019
Sphingosine-1-phosphate (S1P) regulates the proliferation of various cells and promotes the growth of cancer cells. Sphingosine kinase (SK), which transforms sphingosine into S1P, has two isotypes: SK1 and SK2.
Jitendra Shrestha   +10 more
core   +1 more source

Human Dental Pulp Stem Cell Secretome Restores Ischemic Stroke–Impaired Motor and Cognitive Functions by Reprogramming Redox and Inflammatory Signaling

open access: yesAdvanced Science, EarlyView.
Human dental pulp stem cell secretome emerges as a cell‐free therapeutic strategy for ischemic stroke by reprogramming redox and inflammatory signaling. hDPSC secretome‐derived antioxidant and immunomodulatory factors suppress the TLR4–NOX–ROS–NF‐κB axis, reduce microglial inflammatory responses and apoptosis, and promote neurogenesis, angiogenesis ...
Kyung‐Joo Seong   +8 more
wiley   +1 more source

Molecular Basis for Activation to Inhibition Switching in Kv7.2 Channel Modulators

open access: yesAngewandte Chemie, EarlyView.
The paper describes the serendipitous discovery of chemical manipulation allowing the activator‐to‐inhibitor switching in Kv7.2 channel modulators. The molecular determinants driving this switch have been rationalized by multidisciplinary investigation encompassing synthetic and analytical chemistry, in silico methods, cryo‐EM analysis ...
Tania Ciaglia   +20 more
wiley   +2 more sources

Omens on physiognomy, tablet concordance KUB XXV 33 - CTH 543 [PDF]

open access: yes, 2015
Transcription of the omens on physiognomy based on the tablet concordance KUB XXV 33 (inventory no. Bo 2427). Emmanuel Laroche translated this text as "Physiognomonie,” and classified the concordance in the category of divination texts among treatises ...
Gonnet-Bağana, Hatice
core  

Nucleoside‐Modified mRNA Encoding Alpha‐Galactosidase A Ameliorates Fabry Disease Phenotypes in Human IPSC‐Derived Cardiomyocytes

open access: yesAdvanced Science, EarlyView.
Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem   +24 more
wiley   +1 more source

Effects of LncRNA MEG3 on immunity and autophagy of non-small cell lung carcinoma through IDO signaling pathway

open access: yesWorld Journal of Surgical Oncology, 2021
Background The study was done to investigate the effect of LncRNA MEG3 on the immunity and autophagy of non-small cell lung carcinoma through the IDO signaling pathway. Methods A total of 78 cases of early NSCLC patients (research group; RG) and 69 cases
Chuanqiang Wang   +2 more
doaj   +1 more source

Commento art. 543-554 c.p.c. [PDF]

open access: yes, 2018
COMMENTO ARTT.
Laura Durello, Andrea Graziosi
core  

Convergence of Plasmid‐Mediated tmexCD‐toprJ With Critical Resistance Genes Fuels Spread of Multidrug Resistant Bacteria

open access: yesAdvanced Science, EarlyView.
Global dissemination of tmexCD‐toprJ across bacterial hosts and ecological niches is accompanied by its convergence with blaKPC, blaNDM, and mcr on mobile plasmids. Recombination and acquisition of resistance modules generate distinct multidrug resistant plasmid architectures, facilitating the emergence and spread of high‐risk bacterial populations ...
Kaiwen Song   +9 more
wiley   +1 more source

543. Komu-sō [PDF]

open access: yes, 1987
Iwao Seiichi, Iyanaga Teizō, Ishii Susumu, Yoshida Shōichirō, Fujimura Jun'ichirō, Fujimura Michio, Yoshikawa Itsuji, Akiyama Terukazu, Iyanaga Shōkichi, Matsubara Hideichi. 543. Komu-sō. In: Dictionnaire historique du Japon, volume 13, 1987. Lettre K (3)
Iwao, Seiichi   +9 more
core   +2 more sources

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