Vaccarin is a flavonoid glycoside, which has a variety of pharmacological properties and plays a protective role in diabetes and its complications, but its mechanism is unclear. In this study, we aim to investigate whether histone deacetylase 1(HDAC1), a
Taiyue Li+8 more
doaj +2 more sources
To find out the role of hsa‐miR‐570‐3p targeting CD274 in triple negative breast cancer (TNBC) via PI3K/AKT/mTOR signaling pathway. Hsa‐miR‐570‐3p and CD274 expressions in 175 TNBC patients were detected by qRT‐PCR and immunohistochemistry respectively ...
Li‐Li Wang+8 more
doaj +2 more sources
MiR-570 inhibits cell proliferation and glucose metabolism by targeting IRS1 and IRS2 in human chronic myelogenous leukemia [PDF]
Objective(s): Chronic myelogenous leukemia (CML) is a chronic myeloproliferative disorder characterized by the accumulation of myeloid cells with a chromosomal translocation known as the Philadelphia chromosome.
Hong Zhao+7 more
doaj +2 more sources
MicroRNA‐570 is a novel regulator of cellular senescence and inflammaging [PDF]
Diseases of accelerated aging often occur together (multimorbidity), and their prevalence is increasing, with high societal and health care costs. Chronic obstructive pulmonary disease (COPD) is one such condition, in which one half of patients exhibit ≥4 age-related diseases. Diseases of accelerated aging share common molecular pathways, which lead to
Baker, JR+7 more
openaire +5 more sources
العلاقات السياسية اللومباردية - الفرنجية (570 – 604م ) [PDF]
وتتمثل أهمية الدراسة الحالية في رصد وتحليل العلاقات السياسية التي قامت بين المملکتين اللومباردية والفرنجية خلال فترة هامة وحرجة في عمر المملکة اللومباردية ، حيث تم خلالها تثبيت أرکانها ، والتي امتدت منذ بداية العقد الثامن من القرن السادس الميلادي حتى ...
سونيا عبد الوهاب غازي
doaj +2 more sources
A CEERS Discovery of an Accreting Supermassive Black Hole 570 Myr after the Big Bang: Identifying a Progenitor of Massive z > 6 Quasars [PDF]
We report the discovery of an accreting supermassive black hole at z = 8.679. This galaxy, denoted here as CEERS_1019, was previously discovered as a Lyα-break galaxy by Hubble with a Lyα redshift from Keck.
R. Larson+50 more
semanticscholar +1 more source
Constraints on Heavy Decaying Dark Matter from 570 Days of LHAASO Observations. [PDF]
The kilometer square array (KM2A) of the large high altitude air shower observatory (LHAASO) aims at surveying the northern γ-ray sky at energies above 10 TeV with unprecedented sensitivity.
Z. Cao+277 more
semanticscholar +1 more source
Surface Hydrophobic Modification of Biochar by Silane Coupling Agent KH-570
Biochar-amended soil cover (BSC) in landfills can improve the oxidation of methane. However, adding biochar can cause a larger amount of rainwater to enter the soil cover and landfill because it increases the permeability of the soil cover, which ...
Muxi Zhang+6 more
semanticscholar +1 more source
CD44 Gene rs8193 C Allele Is Significantly Enriched in Gastric Cancer Patients [PDF]
Objective: Gastric cancer is a multifactorial disease. In addition to environmental factors, many genes are involved in this malignancy. One of the genes associated with gastric cancer is CD44 gene and its polymorphisms.
Roya Mokhtarian+6 more
doaj +1 more source
Circ_0007444 Inhibits the Progression of Ovarian Cancer via Mediating the miR-570-3p/PTEN Axis
Purpose Some circular RNAs have been found to be effective therapeutic targets for OC. However, the biological function of circ_0007444 in OC is still unknown. Thus, this study investigated the role of circ_0007444 in OC progression. Methods circ_0007444
Xinyu Wu+3 more
semanticscholar +1 more source