Results 101 to 110 of about 32,355 (207)

Protective effects of the thioredoxin and glutaredoxin systems in dopamine-induced cell death [PDF]

open access: yes, 2017
Although the etiology of sporadic Parkinson disease (PD) is unknown, it is well established that oxidative stress plays an important role in the pathogenic mechanism.
Arodin, Lisa   +3 more
core   +1 more source

Assessment of Foeniculum Vulgare L. methanolic extract effect on a model of Parkinson’s disease. induced by ICV injection of 6-hydroxydopamin in female rats, using behavioral tests

open access: yesمجله دانشگاه علوم پزشکی بیرجند, 2015
Background and Aim: Oxidative stresses are involved in neuronal degeneration of substantia nigra and thereby induction of Parkinson's disease. It is reported that Foeniculum Vulgare L.
Hassan Nakisa   +7 more
doaj  

De novo and long-term l-Dopa induce both common and distinct striatal gene profiles in the hemiparkinsonian rat

open access: yesNeurobiology of Disease, 2009
We compared for the first time the effects of de novo versus long-term l-Dopa treatment inducing abnormal involuntary movement on striatal gene profiles and related bio-associations in the 6-hydroxydopamine rat model of Parkinson's disease.
Michèle El Atifi-Borel   +5 more
doaj   +1 more source

The potential of neurotrophic factors for the treatment of Parkinson's disease [PDF]

open access: yes, 2014
Parkinson’s disease (PD) is the second most common neurodegenerative disorder, with an incidence of 1.5 - 2% in the population over 60 years of age, which increases significantly with advancing age (for reviews see de Lau & Breteler, 2006; Toulouse ...
Sullivan, Aideen M., Toulouse, André
core   +1 more source

The Flavonoid Hesperetin Alleviates Behavioral Abnormality in 6-Hydroxydopamine Rat Model of Hemi-Parkinsonism

open access: yesBasic and Clinical Neuroscience, 2011
Parkinson's disease (PD) is a neuropathological and debilitating disorder involving the degeneration of mesencephalic dopaminergic neurons. Neuroprotective effect of hesperetin has already been reported, therefore, this study examined whether the ...
Tourandokht Baluchnejadmojarad   +1 more
doaj  

Neuroprotective effects of exercise with hydroalcoholic extraction of Eriobotrya japonica on MANF in the Brainstem of parkinson’s rats [PDF]

open access: yes, 2014
زمینه و هدف: عصاره هیدروالکی گل گیاه ازگیل ژاپنی غنی از ترکیبات فنلی است. این مطالعه با هدف بررسی اثر محافظتی 12 هفته تمرین چرخ دوار همراه با عصاره گل گیاه ازگیل ژاپنی بر ضایعه القاء شده با تزریق درون بطنی 6- هیدروکسی دوپامین در سطح فاکتور نروتروفیکی ...
Aghasi, M.   +2 more
core  

Dopaminergic Neuroprotection with Ginkgolide in 6-Hydroxydopamine Rat Parkinson’s Disease Model

open access: yesJournal of Mazandaran University of Medical Sciences, 2019
Background and purpose: Parkinson's disease (PD) is a prevalent movement disorder in elderly with progressive motor complications due to antioxidant defense system deficiency and accumulation of degraded proteins in dopaminergic neurons of midbrain ...
Alireza Moghadam   +5 more
doaj  

Dietary and Intraperitoneal Administration of Selenium Provide Comparable Protection in the 6-Hydroxydopamine Lesion Rat Model of Parkinson's Disease [PDF]

open access: yes, 2007
Significant research implicates the involvement of free radicals in the manifestation of Parkinson's disease. The antioxidant, selenium is a vital dietary component for mammals. It is present in the active center of glutathione peroxidase, an antioxidant
Cecilia M. Fox   +2 more
core  

Neuroprotective Effect of Quercetin Nanocrystal in a 6-Hydroxydopamine Model of Parkinson Disease: Biochemical and Behavioral Evidence

open access: yesBasic and Clinical Neuroscience, 2018
Introduction: studies have suggested that free radicals-induced neurodegeneration is one of the many studies of Parkinson Disease (PD). Quercetin as a natural polyphenol has been regarded as a significant player in altering the progression of ...
Fatemeh Ghaffari   +2 more
doaj  

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