Results 191 to 200 of about 32,355 (207)

5,6-dihydroxyindole formation from oxidized 6-hydroxydopamine

European Journal of Pharmacology, 1972
Abstract Within 1 hr oxidized 6-hydroxydopamine solutions at 37°C and pH 7.4 produce significant quantities of 5,6-dihydroxyindole. An analog, 6-aminodopamine, also a powerful norepinephrine depletor in mouse brain, provides the same 5,6-hydroxyindoles.
C L, Blank, P T, Kissinger, R N, Adams
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6-Hydroxydopamine therapy in glaucoma.

Transactions. Section on Ophthalmology. American Academy of Ophthalmology and Otolaryngology, 1977
At the inception of this study, 6-hydroxydopamine (6-HD) was administered to 137 eyes of 100 glaucoma patients by subconjunctival injection (27 applications) and later by iontophoresis (202 applications). Eighty-four patients were receiving maximum medical therapy, and 24 had had previous glaucoma surgery. Seventy-seven had primary open-angle glaucoma.
H, Watanabe, R Z, Levene, M R, Bernstein
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Effect of 6-hydroxydopamine on morphine analgesia

Psychopharmacologia, 1972
The influence of 6-OHDA on morphine analgesia estimated by the hot-plate method was investigated in rats. 6-OHDA injected intraventricularly at a dose of 250 Μg/rat, significantly and specifically depleted catecholamines from the brain. Morphine (7.5 mg/kg) produced a prominent analgesia in untreated and sham-injected rats whilst the reaction times of ...
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Feeding Behavior after Hypothalamic 6-Hydroxydopamine Injections

Appetite, 1984
6-Hydroxydopamine (6-OHDA) injection into the rat hypothalamus produces profound changes in eating behavior and body weight gain. Willis and Smith have demonstrated an anorexic effect of lateral hypothalamic (LH) 6-OHDA, which they correlate with local catecholamine release from degenerating axons just behind the lesion.
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Guanosine Protects Glial Cells Against 6-Hydroxydopamine Toxicity

2014
Increasing body of evidence indicates that neuron-neuroglia interaction may play a key role in determining the progression of neurodegenerative diseases including Parkinson's disease (PD), a chronic pathological condition characterized by selective loss of dopaminergic (DA) neurons in the substantia nigra.
GIULIANI, Patricia, BALLERINI, Patrizia, BUCCELLA, SILVANA, CICCARELLI, Renata, Rathbone, M. P., ROMANO, Silvia, D'ALIMONTE, Iolanda, CACIAGLI, Francesco, DI IORIO, Patrizia, Pokorski, M.   +9 more
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Effect of ceruloplasmin on 6-hydroxydopamine oxidation.

Biochemistry and molecular biology international, 1996
The effects of ceruloplasmin, a blu copper-containing serum glycoprotein, on the oxidation of the neurotoxin 6-hydroxydopamine in several chemical environments were studied. The spontaneous autoxidation of 6-hydroxydopamine proceeded by a free radical chain reaction involving O2-.
MEDDA, ROSARIA, Calabrese L, Musci G, PADIGLIA, ALESSANDRA, Floris G.   +4 more
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The Pharmacology of 6-Hydroxydopamine

Annual Review of Pharmacology, 1973
H, Thoenen, J P, Tranzer
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Pharmacological Actions of 6-Hydroxydopamine

Pharmacological Reviews, 1974
R M, Kostrzewa, D M, Jacobowitz
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6-Hydroxydopamine and striatal acetylcholine levels

Brain Research, 1974
D S, Grewaal, H C, Fibiger, E G, McGeer
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6-Hydroxydopamine

2010
Michael H. Bloch, Michael H. Bloch, Mark A. Geyer, David C. S. Roberts, Eileen M. Joyce, Jonathan P. Roiser, John H. Halpern, Joji Suzuki, Pedro E. Huertas, Torsten Passie, John H. Halpern, Joji Suzuki, Pedro E. Huertas, Torsten Passie, Joji Suzuki, Torsten Passie, Pedro E. Huertas, John H. Halpern, Joji Suzuki, Torsten Passie, Pedro E. Huertas, John H. Halpern, David E. Nichols, Marie-Louise G. Wadenberg, Trevor W. Robbins, David S. Baldwin, Sophie Tambour, John C. Crabbe, Lucio Tremolizzo, Gessica Sala, Carlo Ferrarese, Brian L. Odlaug, Jon E. Grant, Paul D. Callaghan, Iain S. McGregor, Murray R. Thompson, Sarah Morgan, Angus Mackay, E. Ernst, Lawrence H. Price, Michael M. Morgan, MacDonald J. Christie, Susan Jones, Andrew Young, Elizabeth C. Warburton, Stephen J. Hill, Anthony R. Isles, Lawrence S. Wilkinson, Subhash C. Pandey, Subhash C. Pandey, Subhash C. Pandey, Aldo Badiani, James Winslow, Susan Jones, Jill B. Becker, Lucio Tremolizzo, Gessica Sala, Carlo Ferrarese, Paul D. Callaghan, Iain S. McGregor, Murray R. Thompson, David E. Nichols, Jason C. G. Halford, Stephen B. Dunnett, Martine Cador, Naheed (Max) Mirza, Andrea Bari, Yesne Alici, William Breitbart, Andrea Bari, Becky Kinkead, Charles B. Nemeroff, Lucy C. Guillory, Jason C. G. Halford, Ennio Esposito, William Invernizzi, Gary Remington, Tomasz Schneider, Michel Billiard, Michel Billiard, Alyson J. Bond, Paolo Nencini, Michele S. Milella, Brian E. Leonard, Yesne Alici, William Breitbart, Luis de Lecea, Michel Billiard, Samuel B. Hutton, Jason C. G. Halford, R. H. De Rijk, E. R. de Kloet, Tooru M. Mizuno, Maria Isabel Colado, A. Richard Green   +94 more
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