, 1979 A rapid method based on reversed-phase high-performance liquid chromatography is described for the separation and quantitation of azathioprine, 6-mercaptopurine and their potential contaminants and degradants present in dosage forms.
Plag, Plag, Neil, J M, Fell, Anthony F
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Commensal bacteria promote azathioprine therapy failure in inflammatory bowel disease via decreasing 6-mercaptopurine bioavailability. [PDF]
Cell Rep Med, 2023 Yan Y +14 more
europepmc +1 more source
, 2014 Does lymphopenia or macrocytosis reflect therapeutic 6-thioguanine levels in patients with inflammatory bowel disease treated with azathioprine or 6 ...
N Heerasing (13470787) +3 more
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Preparation of 6-Mercaptopurine Loaded Liposomal Formulation for Enhanced Cytotoxic Response in Cancer Cells. [PDF]
Nanomaterials (Basel), 2022 Jamal A +7 more
europepmc +1 more source
Hepatotoxicity of 6-Mercaptopurine and Azathioprine [PDF]
Mayo Clinic Proceedings, 1994 openaire +2 more sources
Low NUDT15 expression levels due to biallelic NUDT15 variants and 6-mercaptopurine intolerance. [PDF]
Br J Haematol, 2022 Yoshida M +23 more
europepmc +1 more source
One Case of Epstein-Barr Virus Encephalitis from Pediatric Crohn's Disease After 6-Mercaptopurine and Infliximab Treatment. [PDF]
Dig Dis Sci, 2023 Yu J, Lv Y, Luo Y, Fang Y, Chen J.
europepmc +1 more source
Preemptive TPMT Genotyping and Adherence to Genotype-Based Therapeutic Recommendations Reduces the Healthcare Cost in Patients Receiving Azathioprine or 6-Mercaptopurine for Autoimmune Diseases. [PDF]
J Pers Med, 2023 Valdez-Acosta S +7 more
europepmc +1 more source
Density functional theory study of the corrosion inhibition performance of 6-mercaptopurine and 6-thioguanine expired drugs toward the aluminium (111) surface. [PDF]
RSC Adv, 2023 Ibrahim MAA +7 more
europepmc +1 more source
Eudragit S100-coated microbeads of thiolated chitosan/casein for pH-responsive colon-targeted delivery of 6-mercaptopurine. [PDF]
RSC AdvHameed H +5 more
europepmc +1 more source