Results 111 to 120 of about 88,642,428 (226)

Pharmacogenetics of 6-mercaptopurine in a black Zimbabwean cohort treated for acute lymphoblastic leukaemia. [PDF]

Pharmacogenomics, 2023
Chikondowa P, Munkombwe D, Chikwambi Z, Kuona P, Masimirembwa C.   +4 more
europepmc   +1 more source

Loading cisplatin onto 6-mercaptopurine covalently modified MSNS: a nanomedicine strategy to improve the outcome of cisplatin therapy

, 2016
Xiaojie Lv,1 Ming Zhao,1,2 Yuiji Wang,1 Xi Hu,1 Jianhui Wu,1 Xueyun Jiang,1 Shan Li,1 Chunying Cui,1 Shiqi Peng1 1Beijing Area Major Laboratory of Peptide and Small Molecular Drugs, Engineering Research Center of Endogenous Prophylactic of Ministry of ...
Wu J, Zhao M, Li S, Lv X, Hu X, Jiang X, Peng S, Wang Y, Cui C   +8 more
core  

Tumor Microenvironment-Responsive 6-Mercaptopurine-Releasing Injectable Hydrogel for Colon Cancer Treatment. [PDF]

Gels, 2023
Kim S, Lee W, Park H, Kim K.
europepmc   +1 more source

Cephalothin as a Carrier of 6-Mercaptopurine for Targeting Cancer Tissues

Iraqi Journal of Pharmaceutical Sciences, 2017
A lower extracellular pH is one of the few well-documented physiological differences between tumour and normal tissues. On the other hand, elevated glutathione (GSH) level has been detected in many tumours compared with healthy surrounding tissues.
Mohammad H. Mohammad, Haider J.Al-Karagully   +1 more
doaj  

Impact of Chronotherapy on 6-Mercaptopurine Metabolites in Inflammatory Bowel Disease: A Pilot Crossover Trial. [PDF]

Clin Transl Gastroenterol, 2023
Swanson GR, Biglin M, Raff H, Chouhan V, Jochum S, Shaikh M, Francey L, Bishehsari F, Hogenesch J, Keshavarzian A.   +9 more
europepmc   +1 more source

Exploring the Enhanced Antiproliferative Activity of Turmeric Oil and 6-Mercaptopurine in a Combined Nano-Particulate System Formulation. [PDF]

Pharmaceutics, 2023
Ahmed TA, Ali EMM, Kalantan AA, Almehmady AM, El-Say KM.   +4 more
europepmc   +1 more source

The influence of NUDT15 variants on 6-mercaptopurine-induced neutropenia in Vietnamese pediatric acute lymphoblastic leukemia. [PDF]

HGG Adv, 2023
Nguyen ML, Hoang AV, Duong BT, Phung NTN.   +3 more
europepmc   +1 more source

STUI)IES ON DRUG RESISTANCE IX MAMMALIAN CELLS. II. 6-MERCAPTOPURINE RESISTANCE IN MOUSE FIBROBLASTS’

, 1959
6-Mercaptopurine (6-MP), developed by Elion et al. (1952), has been utilized in the clinic for the treatment of certain neoplastic disorders and has been the subject of several investigations pertaining to its mechanism of action ...
Lewis Aronow, Aronow, L, Setsuo Tomizawa, Tomizawa, S   +3 more
core  

Early Initiation of Adalimumab Significantly Diminishes Postoperative Crohn's Disease Endoscopic Recurrence and Is Superior to 6-Mercaptopurine Therapy: An Open-Label, Randomized Controlled Study. [PDF]

J Clin Med, 2023
Hirsch A, Scapa E, Fliss-Isakov N, Tulchinsky H, Itzkowitz E, Kariv Y, Ron Y, Yanai H, White I, Yassin S, Cohen NA, Brazovski E, Dotan I, Maharshak N.   +13 more
europepmc   +1 more source

Cellular Uptake and Transport Mechanism of 6-Mercaptopurine Nanomedicines for Enhanced Oral Bioavailability. [PDF]

Int J Nanomedicine, 2023
Zou Y, Gao W, Jin H, Mao C, Zhang Y, Wang X, Mei D, Zhao L.   +7 more
europepmc   +1 more source