Results 101 to 110 of about 9,465,904 (238)

BMT4me En Español: Multisite Feasibility and Usability Testing of a Spanish‐Language mHealth Adherence Support App for Spanish‐Speaking Caregivers of Children After Hematopoietic Stem Cell Transplantation and Cancer Treatment

Pediatric Blood &Cancer, Volume 73, Issue 9, September 2026.
ABSTRACT Background Medication nonadherence during the first 100 days after pediatric hematopoietic stem cell transplantation (HSCT) and during oncology treatment increases risk for complications. BMT4me is a caregiver‐facing mobile health (mHealth) application providing medication reminders, symptom tracking, and note‐taking features to support ...
Micah A. Skeens, Madeline R. Peek, Bianca Franklin, Emre Sezgin, Melissa Beauchemin   +4 more
wiley   +1 more source

Genetic Polymorphism of Thiopurine S-Methyltransferase in Children with Acute Lymphoblastic Leukemia

Pakistan Journal of Medicine and Dentistry
Background: 6-Mercaptopurine (6-MP), a widely used anti-metabolite for the maintenance phase of childhood acute lymphoblastic leukemia (ALL), has been observed to cause myelotoxicity due to genetic polymorphism of thiopurine methyl transferase (TPMT ...
Afrina Raza, Shamil Ashraf, Soofia Nigar, Itimad Abdelsalam Mohamed Ayed   +3 more
doaj   +1 more source

Arabinosyl-6-mercaptopurine and Arabinosyl-6-mercaptopurine-5'-phosphate: Comparison of Their Metabolic Effects

Experimental Biology and Medicine, 1969
SummaryArabinosyl-6-mercaptopurine (Ara-6-MP), an effective inhibitor of the growth of the mouse tumors Ca755, Ehrlich and L1210, was incubated in fortified cellfree extracts of these tumor cells under conditions where 6-methylmercaptopurine riboside and inosine were converted to nucleotide. No nucleotide formation could be detected.
Le page, G A, Bell, J P, Wilson, M J
openaire   +2 more sources

Tracking Health Related Quality of Life From Diagnosis to Follow‐Up Among Australian Children With Acute Lymphoblastic Leukaemia

Pediatric Blood &Cancer, Volume 73, Issue 9, September 2026.
ABSTRACT Background Acute lymphoblastic leukaemia (ALL) is one of the most treatable forms of paediatric cancer; however, there is a substantial burden of treatment‐related toxicities (TRTs). In addition, the long‐term changes in children's health‐related quality of life (HRQoL) due to toxic treatments are not well understood.
Clare Ghows, Clarissa E. Schilstra, Karen McCleary, Nancy E. Briggs, Rishi S. Kotecha, Richard De Abreu Lourenco, Shanti Ramachandran, Ruelleyn Cockcroft, Rachel Conyers, Siobhan Cross, Luciano Dalla‐Pozza, Peter Downie, Tamas Revesz, Michael Osborn, Frank Alvaro, Claire E. Wakefield, Glenn M. Marshall, Toby Trahair, Marion K. Mateos, Joanna E. Fardell   +19 more
wiley   +1 more source

Enzyme@Silicone: A Versatile Combo for Robust Synthetic Biocatalysis?

Advanced Synthesis &Catalysis, Volume 368, Issue 17, 1 September 2026.
Silicone‐based polymers are versatile materials for enzyme immobilization, offering unique advantages such as chemical inertness, thermal stability, and tunable morphology. This review highlights their applications in synthetic biocatalysis, from batch to continuous processes, and addresses key challenges such as mass transport limitations and ...
Marion B. Ansorge‐Schumacher
wiley   +1 more source

Single‐Incision Laparoscopy‐First Strategy in Crohn's Disease: Risk Factors for Conversion and Surgical Outcomes

Annals of Gastroenterological Surgery, Volume 10, Issue 5, Page 1602-1611, September 2026.
In this retrospective study of 289 patients with Crohn's disease undergoing a single‐incision laparoscopy‐first (SILS‐first) strategy, conversion to open surgery was required in only 11.8% of cases. Fistula formation, colon resection, and smoking history were identified as independent risk factors for conversion, while postoperative complications and ...
Yuki Horio, Motoi Uchino, Yusuke Tomoo, Kentaro Nagano, Kurando Kusunoki, Ryuichi Kuwahara, Kei Kimura, Kozo Kataoka, Masataka Ikeda, Hiroki Ikeuchi   +9 more
wiley   +1 more source

Diagnostic BMI and Induction Therapy Weight Change Associated With Hepatotoxicity in Pediatric Patients With Acute Lymphoblastic Leukemia

Cancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Background Hepatotoxicity is a common treatment‐related complication in pediatric acute lymphoblastic leukemia (ALL). Excess adiposity at diagnosis has been identified as a risk factor, but the impact of weight change during therapy has not been examined.
Emily J. Mason, John P. Woodhouse, Jeremy M. Schraw, Joanna S. Yi, Karen R. Rabin, M. Monica Gramatges, Mark C. Zobeck, Baojiang Chen, Melissa B. Harrell, Olga A. Taylor, Michael E. Scheurer, Philip J. Lupo, Van Huynh, Steven D. Mittelman, Etan Orgel, Austin Brown   +15 more
wiley   +1 more source

Prolonged Headache in a 13‐Year‐Old Girl With Acute Lymphoblastic Leukemia: A Case of Possible Neuroinflammatory Complication Responsive to Intravenous Immunoglobulin

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Neurological complications in pediatric acute lymphoblastic leukemia (ALL) may result from disease, CNS involvement, or treatment. We report a 13‐year‐old girl with persistent headache and blurred vision suggestive of raised intracranial pressure.
Amereh Hadizadeh, Hossein Esfahani, Firozeh Hosseini, Afshin Fayyazi, Nasibeh Ghalandari   +4 more
wiley   +1 more source

Efficacy of Interleukin‐12/23 and Interleukin‐23 Inhibitors for Moderately to Severely Active Crohn's Disease in Advanced Treatment Failure Populations: Systematic Review and Network Meta‐Analysis

JCC Plus, Volume 1, Issue 5, September 2026.
ABSTRACT Background and Aims Earlier trials of advanced treatments indicated for moderately to severely active Crohn's disease used predominantly re‐randomized induction responder designs, whereas newer treatments were evaluated using treat‐through designs.
Christopher Ma, Marla Dubinsky, Gil Y. Melmed, Namita Joshi, Jenny Griffith, Fernando Aponte, Brooke Kim, Eric B. Collins, Kristen Westerhoff, Remo Panaccione   +9 more
wiley   +1 more source

The Proctitis Paradox: Refractory Ulcerative Proctitis Associated With Development of Disease Complications in a Multicenter South Australian Cohort

JGH Open, Volume 10, Issue 9, September 2026.
ABSTRACT Background Despite limited extent, patients with ulcerative proctitis (UP) can suffer from debilitating symptoms, complications, and risk of disease extension. The aim was to provide a contemporary real‐world insight into the management and outcomes of UP.
Sreecanth S. Raja, Samuel P. Costello, Alexandra Sadler, Nicholas Wan, Bhuwan Tandon, Dharshan Sathananthan, Kate D. Lynch, Chris K. Rayner, Suzanne Edwards, Robert V. Bryant   +9 more
wiley   +1 more source