Results 81 to 90 of about 9,465,904 (238)

Does CytoSorb Interfere with Immunosuppression? A Pharmacokinetic and Functional Evaluation

Pharmaceutics
Background/Objectives: Cytokine release during organ transplantation contributes to primary graft dysfunction and requires careful immunomodulation. CytoSorb, a hemoadsorption device developed to reduce circulating cytokine levels, is increasingly used ...
Stephan Harm, Claudia Schildböck, Denisa Cont, Viktoria Weber, Jens Hartmann   +4 more
doaj   +1 more source

Partnered Pharmacist Medication Charting for Children and Young People: A Retrospective Cohort Study

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim Partnered pharmacist medication charting (PPMC) reduces medication errors in Australian adult hospitals. This study evaluated the impact of PPMC on paediatric emergency department (ED) presentations compared to early best possible medication history (BPMH) and usual care.
Georgia Lloyd, Brooke McCarthy, Polly Ng, Christopher Johansson, Felicity Wright   +4 more
wiley   +1 more source

Hair loss in pediatric inflammatory bowel disease: Clinical recognition and implications for care

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Angela Anaeme, Liza Siegel, Meryl Perlman   +2 more
wiley   +1 more source

Salivary Methotrexate as a Predictor of Oral Mucositis in Hematological Cancer Patients: A Phase II Randomized, Double‐Blind Clinical Trial

Oral Diseases, EarlyView.
ABSTRACT Objective To evaluate the efficacy of prophylactic photobiomodulation therapy (PBMT) in preventing oral mucositis (OM) and to assess serum and salivary methotrexate (MTX) levels as predictors of OM in adults receiving high‐dose methotrexate (HD‐MTX).
Letícia Rodrigues‐Oliveira, Carolina Guimarães Bonfim, Ana Leticia Mores, Natalia Rangel Palmier, Henrique Ballassini Abdalla, Juliana Trindade Clemente‐Napimoga, Iara Gonçalves Aquino, Maria Cecilia Querido de Oliveira, Maria Cláudia Cuzzullin, Aljomar Jose Vechiato Filho, Cesar Rivera, Tatiana Natasha Toporcov, Juliana Pereira, Luiz Alcino Gueiros, Rossana Veronica Mendoza López, Manoela Domingues Martins, Marcelo Lazzaron Lamers, Karina Morais‐Faria, Pablo Agustin Vargas, Alan Roger Santos‐Silva, Thais Bianca Brandão, Ana Carolina Prado‐Ribeiro   +21 more
wiley   +1 more source

Loading cisplatin onto 6-mercaptopurine covalently modified MSNS: a nanomedicine strategy to improve the outcome of cisplatin therapy

, 2016
Xiaojie Lv,1 Ming Zhao,1,2 Yuiji Wang,1 Xi Hu,1 Jianhui Wu,1 Xueyun Jiang,1 Shan Li,1 Chunying Cui,1 Shiqi Peng1 1Beijing Area Major Laboratory of Peptide and Small Molecular Drugs, Engineering Research Center of Endogenous Prophylactic of Ministry of ...
Wu J, Zhao M, Li S, Lv X, Hu X, Jiang X, Peng S, Wang Y, Cui C   +8 more
core  

Azathioprine and 6-Mercaptopurine-induced Liver Injury: Clinical Features and Outcomes. [PDF]

, 2017
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/OpenThe objective of the study was to define the clinical, biochemical, and histologic features of liver injury from thiopurines.Azathioprine (Aza) and 6 ...
Björnsson, Einar S, Gu, Jiezhun, Hoofnagle, Jay H, Kleiner, David E., Hoofnagle, Jay H., Chalasani, Naga, Kleiner, David E, Hayashi, Paul H, Hayashi, Paul H., Björnsson, Einar S.   +9 more
core   +2 more sources

An improved HPLC method for the quantitation of 6-mercaptopurine and its metabolites in red blood cells

Brazilian Journal of Medical and Biological Research, 2004
A procedure is described for the rapid determination of the intra-erythrocyte concentration of 6-mercaptopurine (6-MP) and its metabolites, 6-thioguanine nucleotides (6-TGN) and 6-methylmercaptopurine (6-MMP).
B.M. Oliveira, A.J. Romanha, T.M.A. Alves, M.B. Viana, C.L. Zani   +4 more
doaj   +1 more source

TNFSF14/LIGHT responses in intestinal and oesophageal fibroblasts are differentially modulated by hydroxylase inhibitors

The Journal of Physiology, EarlyView.
Abstract figure legend LIGHT is a mutual mediator of intestinal and oesophageal fibroblast inflammation with common as well as tissue‐specific effects. Hydroxylase inhibitors can selectively suppress inflammatory factors in both cell types, albeit targeting different signalling pathways.
Cian M. Ohlendieck, Carlos Matellan, Cristina Bauset, Bella Raphael, Mary Nwaezeigwe, Emer Flynn, Kevin Okamoto, Desmond Winter, Colm Collins, Katie Doogan, Seán T. Martin, Glen Doherty, Seema S. Aceves, Mario C. Manresa   +13 more
wiley   +1 more source

Metronomic therapy with oral 6-mercaptopurine in elderly acute myeloid leukemia: A prospective pilot study

South Asian Journal of Cancer, 2016
Introduction: Acute myeloid leukemia (AML) in elderly patients differs biologically from that in younger patients and is known to have unfavorable chromosomal rearrangements, higher resistance, and lower tolerance to chemotherapy.
Akhil Kapoor, Surender Kumar Beniwal, Ashok Kalwar, Mukesh Kumar Singhal, Raj Kumar Nirban, Harvindra Singh Kumar   +5 more
doaj   +1 more source

Polyglycolic Acid Shield Prevents Repeated Delayed Bleeding After Endoscopic Stricturotomy for Anastomotic Stricture in Crohn's Disease: A Case Report

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Endoscopic stricturotomy (ES) is a novel approach for treating benign strictures of the lower gastrointestinal tract. However, it is performed at a limited number of facilities, and strategies for preventing complications have not yet been established. We performed ES for ileo‐sigmoid anastomosis associated with Crohn's disease (CD).
Hidezumi Kikuchi, Taka Asari, Tetsuya Tatsuta, Kazuhiro Nagane, Kentaro Hoshi, Shohei Igarashi, Takato Maeda, Yasuhisa Murai, Shinji Ota, Hirotake Sakuraba   +9 more
wiley   +1 more source