Results 81 to 90 of about 88,642,428 (226)

Hair loss in pediatric inflammatory bowel disease: Clinical recognition and implications for care

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Angela Anaeme, Liza Siegel, Meryl Perlman   +2 more
wiley   +1 more source

Polyglycolic Acid Shield Prevents Repeated Delayed Bleeding After Endoscopic Stricturotomy for Anastomotic Stricture in Crohn's Disease: A Case Report

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Endoscopic stricturotomy (ES) is a novel approach for treating benign strictures of the lower gastrointestinal tract. However, it is performed at a limited number of facilities, and strategies for preventing complications have not yet been established. We performed ES for ileo‐sigmoid anastomosis associated with Crohn's disease (CD).
Hidezumi Kikuchi, Taka Asari, Tetsuya Tatsuta, Kazuhiro Nagane, Kentaro Hoshi, Shohei Igarashi, Takato Maeda, Yasuhisa Murai, Shinji Ota, Hirotake Sakuraba   +9 more
wiley   +1 more source

Temporal Dilution: Chemotherapy, Capitalism, and the Making of Cancer Time in Colombia

The Journal of Latin American and Caribbean Anthropology, Volume 31, Issue 4, December 2026.
ABSTRACT Through the ethnographic case of a man undergoing chemotherapy for prostate cancer at a hospital in Colombia, this article examines how chemotherapy schedules make toxicity clinically manageable while imposing rhythms that many patients cannot sustain. It develops an analytic framework centered on three interrelated temporal dynamics: temporal
Camilo Sanz
wiley   +1 more source

Pharmacogenomics in Cancer Treatment: Challenges and Opportunities in African Settings

Cancer Medicine, Volume 15, Issue 11, November 2026.
ABSTRACT Background Cancer incidence in Africa is projected to reach 2.1 million new cases annually by 2040. Current treatment guidelines remain largely based on pharmacogenomic data predominantly from European and Asian genetic profiles, potentially compromising safety and efficacy in African patients.
Ntombikhona Fortunate Maphumulo, George Rebello, Veron Ramsuran   +2 more
wiley   +1 more source

Gold Nanoparticles Enhance the Anti-Leukemia Action of a 6-Mercaptopurine Chemotherapeutic Agent

, 2016
6-Mercaptopurine and its riboside derivatives are some of the most widely utilized anti-leukemic and anti-inflammatory drugs. Their short biological half-life and severe side effects limit their use.
Paul Podsiadlo (1990147), Vladimir A. Sinani (2459356), Joong Hwan Bahng (1443691), Jungwoo Lee (433946), Nadine Wong Shi Kam (2398273), Nicholas A. Kotov (534991)   +5 more
core   +1 more source

Eltrombopag during induction chemotherapy in older patients with newly diagnosed acute myeloid leukemia is safe and reduces platelet transfusion requirements: The EPAG‐2015 French Innovative Leukemia Organization phase 2 randomized trial

Cancer, Volume 132, Issue 21, 1 November 2026.
Abstract Background Elderly patients with acute myeloid leukemia (AML) treated with intensive chemotherapy are at risk of developing thrombopenia, which requires platelet transfusions. It would be interesting to provide them with thrombopoietin receptor agonists such as eltrombopag.
Arnaud Pigneux, Pierre‐Yves Dumas, Marc Bernard, Norbert Vey, Audrey Bidet, Ariane Mineur, Aline Schmidt, Martin Carré, Mario Ojeda, Sarah Bertoli, Anne Banos, Pierre Peterlin, Romain Guièze, Yohan Desbrosses, Gabrielle Roth Guepin, Célestine Simand, Thibaut Leguay, Emmanuel Gyan, Eric Jourdan, Jean‐Philippe Vial, Tony Marchand, Yosr Hicheri, Marie C. Béné, Jean Francois Hamel, Christian Récher   +24 more
wiley   +1 more source

Clinical Functional Assignment of TPMT and NUDT15 Alleles by the Clinical Pharmacogenetics Implementation Consortium Pharmacogene Curation Expert Panel

Clinical Pharmacology &Therapeutics, Volume 120, Issue 5, Page 1427-1437, November 2026.
The Clinical Pharmacogenetics Implementation Consortium (CPIC) TPMT/NUDT15 Pharmacogene Curation Expert Panel (PCEP) conducted a comprehensive review of clinical, laboratory, and computational evidence to determine the clinical function assignments for TPMT and NUDT15 star alleles.
Bailey M. Tibben, Maud Maillard, Victoria M. Pratt, Ann M. Moyer, Debbie M. Figueroa, Michelle Whirl‐Carrillo, Andrea Gaedigk, Gabriele Stocco, Matthias Schwab, Kelly E. Caudle, Jun J. Yang   +10 more
wiley   +1 more source

Cancer Treatment During Pregnancy and Maternal and Infant Outcomes: A Descriptive Cohort Study Using a Japanese Claims Database

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 11, November 2026.
ABSTRACT Purpose To characterize cancer treatment during pregnancy and maternal and infant outcomes among women with cancer identified during pregnancy in Japan. Methods In this descriptive cohort study, we used mother‐infant linkage data from the JMDC claims database from 2005 to 2024.
Masami Tsuchiya, Tomofumi Ishikawa, Takamasa Sakai, Satoko Hori, Taku Obara   +4 more
wiley   +1 more source

Polarographic and voltammetric determination of 6-mercaptopurine and 6-thioguanine

, 1986
Conditions were found for the determination of 6-mercaptopurine (I) and 6-thioguanine (II) by TAST polarography, differential pulse polarography and fast-scan differential pulse voltammetry at a hanging mercury drop electrode.
Ludmila Dempírová, Jiří Zima, Antonín Berka, Jiří Barek   +3 more
core   +1 more source

Diethylene Glycol‐Linked Ring‐Fused Bis‐Azoles: Target‐Oriented Synthesis, In Silico Screening, and Antitumor Activity

ChemMedChem, Volume 21, Issue 19, 14 October 2026.
A series of diethylene glycol‐linked cyclic derivatives with diversity in the heterocyclic motif have been synthesized and screened for antitumor activity. Two bis‐thiazolo[3,2‐a]pyrimidinone derivatives displayed moderate cytotoxicity, high selectivity against hepatocellular carcinoma cells, promising VEGFR2, and remarkable FGFR2 inhibitory activities
Sami A. Al‐Hussain, Abdulrahman S. Alharbi, Zeinab A. Muhammad, Alyaa S. Abdel Halim, Magdi E. A. Zaki, Mark C. Bagley, Refaie M. Kassab   +6 more
wiley   +1 more source