Results 11 to 20 of about 728 (114)

Identification of causal intervention effects under contagion

open access: yesJournal of Causal Inference, 2021
Defining and identifying causal intervention effects for transmissible infectious disease outcomes is challenging because a treatment – such as a vaccine – given to one individual may affect the infection outcomes of others. Epidemiologists have proposed
Cai Xiaoxuan   +2 more
doaj   +1 more source

Evolutionary trend of SARS-CoV-2 inferred by the homopolymeric nucleotide repeats

open access: yesComputational and Mathematical Biophysics, 2022
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the current global COVID-19 pandemic, in which millions of lives have been lost.
Yin Changchuan
doaj   +1 more source

Attributable fraction and related measures: Conceptual relations in the counterfactual framework

open access: yesJournal of Causal Inference, 2023
The attributable fraction (population) has attracted much attention from a theoretical perspective and has been used extensively to assess the impact of potential health interventions. However, despite its extensive use, there is much confusion about its
Suzuki Etsuji, Yamamoto Eiji
doaj   +1 more source

Evaluating early pandemic response through length-of-stay analysis of case logs and epidemiological modeling: A case study of Singapore in early 2020

open access: yesComputational and Mathematical Biophysics, 2023
It is now known that early government interventions in pandemic management helps in slowing down the pandemic in the initial phase, during which a conservative basic reproduction number can be maintained.
Sreevalsan-Nair Jaya   +4 more
doaj   +1 more source

Towards Prediction of HCV Therapy Efficiency

open access: yesComputational and Mathematical Methods in Medicine, Volume 11, Issue 2, Page 185-199, 2010., 2010
We investigate a correlation between genetic diversity of hepatitis C virus population and the level of viral RNA accumulation in patient blood. Genetic diversity is defined as the mean Hamming distance between all pairs of virus RNA sequences representing the population. We have found that a low Hamming distance (i.e. low genetic diversity) correlates
Szymon Wasik   +6 more
wiley   +1 more source

Minimally capturing heterogeneous complier effect of endogenous treatment for any outcome variable

open access: yesJournal of Causal Inference, 2023
When a binary treatment DD is possibly endogenous, a binary instrument δ\delta is often used to identify the “effect on compliers.” If covariates XX affect both DD and an outcome YY, XX should be controlled to identify the “XX-conditional complier ...
Lee Goeun   +2 more
doaj   +1 more source

Solving the 100 Swiss Francs Problem [PDF]

open access: yes, 2011
Sturmfels offered 100 Swiss Francs in 2005 to a conjecture, which deals with a special case of the maximum likelihood estimation for a latent class model.
B. Buchberger   +9 more
core   +2 more sources

Inferences for Joint Modelling of Repeated Ordinal Scores and Time to Event Data

open access: yesComputational and Mathematical Methods in Medicine, Volume 11, Issue 3, Page 281-295, 2010., 2010
In clinical trials and other follow‐up studies, it is natural that a response variable is repeatedly measured during follow‐up and the occurrence of some key event is also monitored. There has been a considerable study on the joint modelling these measures together with information on covariates.
Arindom Chakraborty, Kalyan Das
wiley   +1 more source

Optimal balancing of time-dependent confounders for marginal structural models

open access: yesJournal of Causal Inference, 2021
Marginal structural models (MSMs) can be used to estimate the causal effect of a potentially time-varying treatment in the presence of time-dependent confounding via weighted regression.
Kallus Nathan, Santacatterina Michele
doaj   +1 more source

Generalized Fokker–Planck Theory for Electron and Photon Transport in Biological Tissues: Application to Radiotherapy

open access: yesComputational and Mathematical Methods in Medicine, Volume 11, Issue 4, Page 313-339, 2010., 2010
In this paper, we study a deterministic method for particle transport in biological tissues. The method is specifically developed for dose calculations in cancer therapy and for radiological imaging. Generalized Fokker–Planck (GFP) theory [Leakeas and Larsen, Nucl. Sci. Eng. 137 (2001), pp.
Edgar Olbrant, Martin Frank
wiley   +1 more source

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