Results 11 to 20 of about 751 (132)

Evaluating early pandemic response through length-of-stay analysis of case logs and epidemiological modeling: A case study of Singapore in early 2020

open access: yesComputational and Mathematical Biophysics, 2023
It is now known that early government interventions in pandemic management helps in slowing down the pandemic in the initial phase, during which a conservative basic reproduction number can be maintained.
Sreevalsan-Nair Jaya   +4 more
doaj   +1 more source

Minimally capturing heterogeneous complier effect of endogenous treatment for any outcome variable

open access: yesJournal of Causal Inference, 2023
When a binary treatment DD is possibly endogenous, a binary instrument δ\delta is often used to identify the “effect on compliers.” If covariates XX affect both DD and an outcome YY, XX should be controlled to identify the “XX-conditional complier ...
Lee Goeun   +2 more
doaj   +1 more source

Optimal balancing of time-dependent confounders for marginal structural models

open access: yesJournal of Causal Inference, 2021
Marginal structural models (MSMs) can be used to estimate the causal effect of a potentially time-varying treatment in the presence of time-dependent confounding via weighted regression.
Kallus Nathan, Santacatterina Michele
doaj   +1 more source

Optimal weighting for estimating generalized average treatment effects

open access: yesJournal of Causal Inference, 2022
In causal inference, a variety of causal effect estimands have been studied, including the sample, uncensored, target, conditional, optimal subpopulation, and optimal weighted average treatment effects.
Kallus Nathan, Santacatterina Michele
doaj   +1 more source

Testing for treatment effect twice using internal and external controls in clinical trials

open access: yesJournal of Causal Inference, 2023
Leveraging external controls – relevant individual patient data under control from external trials or real-world data – has the potential to reduce the cost of randomized controlled trials (RCTs) while increasing the proportion of trial patients given ...
Yi Yanyao, Zhang Ying, Du Yu, Ye Ting
doaj   +1 more source

How to reduce the number of rating scale items without predictability loss? [PDF]

open access: yes, 2017
Rating scales are used to elicit data about qualitative entities (e.g., research collaboration). This study presents an innovative method for reducing the number of rating scale items without the predictability loss. The "area under the receiver operator
Araya, R.   +7 more
core   +6 more sources

Towards Prediction of HCV Therapy Efficiency

open access: yesComputational and Mathematical Methods in Medicine, Volume 11, Issue 2, Page 185-199, 2010., 2010
We investigate a correlation between genetic diversity of hepatitis C virus population and the level of viral RNA accumulation in patient blood. Genetic diversity is defined as the mean Hamming distance between all pairs of virus RNA sequences representing the population. We have found that a low Hamming distance (i.e. low genetic diversity) correlates
Szymon Wasik   +6 more
wiley   +1 more source

Inferences for Joint Modelling of Repeated Ordinal Scores and Time to Event Data

open access: yesComputational and Mathematical Methods in Medicine, Volume 11, Issue 3, Page 281-295, 2010., 2010
In clinical trials and other follow‐up studies, it is natural that a response variable is repeatedly measured during follow‐up and the occurrence of some key event is also monitored. There has been a considerable study on the joint modelling these measures together with information on covariates.
Arindom Chakraborty, Kalyan Das
wiley   +1 more source

Generalized Fokker–Planck Theory for Electron and Photon Transport in Biological Tissues: Application to Radiotherapy

open access: yesComputational and Mathematical Methods in Medicine, Volume 11, Issue 4, Page 313-339, 2010., 2010
In this paper, we study a deterministic method for particle transport in biological tissues. The method is specifically developed for dose calculations in cancer therapy and for radiological imaging. Generalized Fokker–Planck (GFP) theory [Leakeas and Larsen, Nucl. Sci. Eng. 137 (2001), pp.
Edgar Olbrant, Martin Frank
wiley   +1 more source

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