Results 51 to 60 of about 2,002,827 (334)

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

Active surveillance for adult low-risk papillary thyroid microcarcinoma—a review focused on the 30-year experience of Kuma Hospital—

open access: yesEndocrine Journal
Active surveillance (AS) for low-risk papillary thyroid microcarcinoma (PTMC), which was initiated at Kuma Hospital (Kobe, Japan) in 1993 and Cancer Institute Hospital (Tokyo) in 1995, is now gradually being adopted worldwide, and several prospective ...
Yasuhiro Ito   +4 more
doaj   +1 more source

Experimental Verification of the Number Relation at Room and Elevated Temperatures [PDF]

open access: yes, 1983
The accuracy of the Neuber equation for predicting notch root stress-strain behavior at room temperature and at 650 C was experimentally investigated.
Lucas, L. J., Martin, J. F.
core   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Current status of the thyroid hormone measurement items in patients receiving levothyroxine monotherapy by the management based on the thyroid tissue volume

open access: yesEndocrine Journal
We and other investigators reported that mild TSH suppression with levothyroxine (LT4) was needed to achieve normal free triiodothyronine (FT3) levels and metabolic euthyroid state in athyreotic patients. Consequently, management methods based on thyroid
Mitsuru Ito   +9 more
doaj   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang   +10 more
wiley   +1 more source

Psych 650,Uop Psych 650,Psych 650 Entire Course New

open access: yes, 2018
UOP PSYCH 650 Week 1 Individual Assignment Perceptions and Causes of Psycho-pathology (2 Papers) NEW Check this A+ tutorial guideline at http://www.assignmentcloud.com/psych-650-uop/psych-650-week-1-individual-assignment-perceptions-and-causes-of-psycho-pathology-new For more classes visit http://www.assignmentcloud.com This Tutorial ...
openaire   +1 more source

APOE genetic variants and apoE, miR-107 and miR-650 levels in Alzheimer's disease.

open access: yesFolia Neuropathologica, 2019
Alzheimer's disease (AD) is a progressive neurodegenerative dementia in adults. Pathogenesis of AD depends on various factors, including APOE genetic variants, apolipoprotein E (apoE) phenotype and oxidative stress, which may promote both DNA and RNA ...
Michal Prendecki   +7 more
semanticscholar   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann   +17 more
wiley   +1 more source

Decompositions of Rational Gabor Representations [PDF]

open access: yes, 2014
Let $\Gamma=\langle T_{k},M_{l}:k\in\mathbb{Z}^{d},l\in B\mathbb{Z}% ^{d}\rangle $ be a group of unitary operators where $T_{k}$ is a translation operator and $M_{l}$ is a modulation operator acting on $L^{2}\left( \mathbb{R}^{d}\right) .$ Assuming that $
Oussa, Vignon
core   +2 more sources

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