Results 171 to 180 of about 13,198 (194)

ChemInform Abstract: OZONOLYSIS OF 7‐DEHYDROCHOLESTEROL ACETATE PEROXIDE

Chemischer Informationsdienst, 1980
AbstractDie Ozonolyse des bekannten Dehydrocholesterinacetat‐peroxides (I) liefert die Folgeprodukte (II)‐(IV), die isoliert und identifiziert werden.
J. GUMULKA, W. J. SZCZEPEK, Z. WIELOGORSKI   +2 more
openaire   +1 more source

7-Dehydrocholesterol is an endogenous suppressor of ferroptosis

Nature
Ferroptosis is a form of cell death that has received considerable attention not only as a means to eradicate defined tumour entities but also because it provides unforeseen insights into the metabolic adaptation that tumours exploit to counteract phospholipid oxidation1,2.
Florencio Porto Freitas, Hamed Alborzinia, Ancély Ferreira dos Santos, Palina Nepachalovich, Lohans Pedrera, Omkar Zilka, Alex Inague, Corinna Klein, Nesrine Aroua, Kamini Kaushal, Bettina Kast, Svenja M. Lorenz, Viktoria Kunz, Helene Nehring, Thamara N. Xavier da Silva, Zhiyi Chen, Sena Atici, Sebastian G. Doll, Emily L. Schaefer, Ifedapo Ekpo, Werner Schmitz, Aline Horling, Peter Imming, Sayuri Miyamoto, Ann M. Wehman, Thiago C. Genaro-Mattos, Karoly Mirnics, Lokender Kumar, Judith Klein-Seetharaman, Svenja Meierjohann, Isabel Weigand, Matthias Kroiss, Georg W. Bornkamm, Fernando Gomes, Luis Eduardo Soares Netto, Manjima B. Sathian, David B. Konrad, Douglas F. Covey, Bernhard Michalke, Kurt Bommert, Ralf C. Bargou, Ana Garcia-Saez, Derek A. Pratt, Maria Fedorova, Andreas Trumpp, Marcus Conrad, José Pedro Friedmann Angeli   +46 more
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ChemInform Abstract: A NEW SYNTHESIS OF 7‐DEHYDROCHOLESTEROLS

Chemischer Informationsdienst, 1981
AbstractCholesterolacetat (I) wird zu (II) und seinem Stereoisomeren bromiert.
P. N. CONFALONE, I. D. KULESHA, M. R. USKOKOVIC   +2 more
openaire   +1 more source

Evaluation of cytotoxic effects of 7-dehydrocholesterol on melanoma cells

Free Radical Biology and Medicine, 2014
Ultraviolet radiation is the main cause of skin cancers, and melanoma is the most serious form of tumor. There is no therapy for advanced-stage melanoma and its metastasis because of their high resistance to various anticancer therapies. Human skin is an important metabolic organ in which occurs photoinduced synthesis of vitamin D3 from 7 ...
GELZO, MONICA, GRANATO, GIUSEPPINA, ALBANO, FRANCESCO, ARCUCCI, ALESSANDRO, DELLO RUSSO, ANTONIO, DE VENDITTIS, EMMANUELE, RUOCCO, MARIA ROSARIA, Corso G.   +7 more
openaire   +4 more sources

The site of 7-dehydrocholesterol ultraviolet photolysis in domestic fowls

Acta Histochemica, 1983
The site of the photolytic reaction leading to Vitamin D3 in fowls integument has been investigated by histochemical and biochemical analysis. The Vitamin D3 precursor, 7-dehydrocholesterol, is synthetized and stored mainly in the uropygial gland and in the same localization several amount of Vitamin D3 may be biochemically detected.
B, Uva, A, Mandich, M, Vallarino
openaire   +2 more sources

7-Dehydrocholesterol: A sterol shield against an iron sword

Molecular Cell
Li et al. and Freitas et al. recently identified 7-dehydrocholesterol (7-DHC), a sterol produced through the cholesterol biosynthetic pathway, as a lipid-soluble antioxidant that protects cells from ferroptosis, a cell death pathway triggered by iron-catalyzed phospholipid peroxidation.1,2.
Shaojie Cui, Jin Ye
openaire   +2 more sources

Inhibition of human fibroblasts sphingomyelinase by cholesterol and 7-dehydrocholesterol

Biochemical and Biophysical Research Communications, 1981
Abstract An inhibition of human fibroblast sphingomyelinase by cholesterol and 7-dehydrocholesterol is shown. This effect is obtained for cholesterol and 7-dehydrocholesterol/sphingomyelin molar ratios above 0.1. Diffusion measurements performed on mixed liposomes demonstrated for cholesterol/sphingomyelin and 7-dehydrocholesterol/sphingomyelin molar
J C, Maziere, C, Wolf, C, Maziere, L, Mora, G, Bereziat, J, Polonovski   +5 more
openaire   +2 more sources

Intestinal sterols. I. Δ7-cholestenol and 7-dehydrocholesterol in feces

Archives of Biochemistry and Biophysics, 1955
1. 1. Fecal sterols from rats on a fat-free diet were found to contain substantial amounts of fast-acting sterols. Chromatography of the unsaponifiable matter resulted in the isolation of Δ7-cholestenol, cholesterol, and coprosterol, and in the identification of 7-dehydrocholesterol. 2. 2.
Wells, W W, Coleman, D L, Baumann, C A
openaire   +2 more sources

Effects of Tween 80 on liver microsomal 7-dehydrocholesterol reductase

Biochemical and Biophysical Research Communications, 1978
Abstract Enzymatic conversion of 7-dehydrocholesterol to cholesterol by liver microsomes was increased by addition of Tween 80. This increase was proportional to Tween 80 concentration, and reached its maximum of 250% of baseline activity after addition of 300 μg/ml of Tween 80.
M V, Srikantaiah, S, Assef, R J, Morin
openaire   +2 more sources

Probing the Biexponential Dynamics of Ring-Opening in 7-Dehydrocholesterol

The Journal of Physical Chemistry A, 2016
Our prior discovery of a novel biexponential photochemical ring-opening in 7-dehydrocholesterol (DHC) to previtamin D3 [ Tang J. Chem. Phys. 2011 , 134 , 104503 ] is further explored with ultrafast transient absorption spectroscopy, and the results are compared with recently reported high-level theoretical calculations.
Broc D, Smith, Kenneth G, Spears, Roseanne J, Sension   +2 more
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