Results 1 to 10 of about 23,028 (215)

Temperature stability of urinary F2-isoprostane and 8-hydroxy-2′-deoxyguanosine [PDF]

Practical Laboratory Medicine
Background: Clinical and epidemiological studies employ long-term temperature storage but the effect of temperature on the stability of oxidative stress (OS) markers is unknown.
Katarzyna Kordas, Diala Ghazal, Elena I. Queirolo, James R. Olson, María Inés Beledo, Richard W. Browne   +5 more
doaj   +4 more sources

DNA oxidative damage in oral cancer: 8-hydroxy-2´-deoxyguanosine immunoexpression assessment. [PDF]

Med Oral Patol Oral Cir Bucal, 2023
The development and establishment of oral squamous cell carcinoma are confined to carcinogenesis, which involves oxidative stress via oxygen-free radical production as a hydroxyl radical (HO•), considered the most important cause of oxidative damage to basic biomolecules since it targets DNA strands. 8-Hydroxy-2´-deoxyguanosine (8-OHdG) is considered a
Prieto-Correa JR, Bologna-Molina R, González-González R, Molina-Frechero N, Soto-Ávila JJ, Isiordia-Espinoza M, Márquez MC, Verdín SL.   +7 more
europepmc   +4 more sources

Urinary 8-Hydroxy-2'-Deoxyguanosine Levels and Cardiovascular Disease Incidence in Japan. [PDF]

J Atheroscler Thromb, 2020
The association between urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG), an oxidative stress marker, and the incidence of cardiovascular disease (CVD) has not been confirmed because no previous studies evaluated 24-hour 8-OHdG excretion levels in the general population. We aimed to confirm the association between 24-hour urinary 8-OHdG levels and CVD risk
Nagao M, Kobashi G, Umesawa M, Cui R, Yamagishi K, Imano H, Okada T, Kiyama M, Kitamura A, Sairenchi T, Haruyama Y, Ohira T, Iso H, CIRCS Investigators.   +13 more
europepmc   +4 more sources

The Concentration of 8-Hydroxy-2?-Deoxyguanosine in Plasma During the Menstrual Cycle in Young Japanese Women [PDF]

Women's Health Reports, 2022
Background: The exact pathophysiology of premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD) is still unknown. This study aimed to investigate the concentration of 8-hydroxy-2?-deoxyguanosine (8-OHdG) in plasma in relation to the ...
Kaori Yama, Honoka Shinbo, Yuka Fujikane, Chiaki Mikami, Maiko Machida, Jun Miura   +5 more
doaj   +2 more sources

Prognostic significance of 8-hydroxy-2′-deoxyguanosine in solid tumors: a meta-analysis [PDF]

BMC Cancer, 2019
Background High level of reactive oxygen species (ROS) has been detected in almost all cancers, which make it become one of the best-characterized phenotypes in cancers.
Xiangcheng Qing, Deyao Shi, Xiao Lv, Baichuan Wang, Songfeng Chen, Zengwu Shao   +5 more
doaj   +2 more sources

Mitochondrial 8-hydroxy-2′-deoxyguanosine and coronary artery disease in patients with type 2 diabetes mellitus [PDF]

Cardiovascular Diabetology, 2020
Background Little is known about whether mitochondria 8-hydroxy-2′-deoxyguanosine (8-OHdG), a biomarker of mitochondrial DNA (mtDNA) oxidative damage, contributes to the development of coronary artery disease (CAD) in diabetic patients. Here, we explored
Xue-bin Wang, Ning-hua Cui, Xia’nan Liu, Xin Liu   +3 more
doaj   +2 more sources

Detection of 8-Hydroxy-2′-Deoxyguanosine Biomarker with a Screen-Printed Electrode Modified with Graphene [PDF]

Sensors, 2019
In this work we present the preparation of graphene material by exfoliation of graphite rods via pulses of current in electrolyte, containing a mixture of boric acid (0.05 M) and sodium chloride (0.05 M). The material was morphologically and structurally
Codruta Varodi, Florina Pogacean, Maria Coros, Marcela-Corina Rosu, Raluca-Ioana Stefan-van Staden, Emese Gal, Lucian-Barbu Tudoran, Stela Pruneanu, Simona Mirel   +8 more
doaj   +2 more sources

Increased Plasma Levels of 8-Hydroxy-2′-deoxyguanosine (8-OHdG) in Patients with Pseudoexfoliation Glaucoma [PDF]

Journal of Ophthalmology, 2019
Purpose. To investigate systemic oxidative stress-induced DNA damage in patients with pseudoexfoliation glaucoma (PXG), we estimated plasma levels of 8-hydroxy-2′-deoxyguanosine (8-OHdG) as a marker for oxidative DNA damage in comparison to controls.
Altaf A. Kondkar, Tahira Sultan, Taif A. Azad, Lubna Tabussum, Essam A. Osman, Saleh A. Al-Obeidan   +5 more
doaj   +2 more sources

Measuring urinary 8-hydroxy-2′-deoxyguanosine and malondialdehyde levels in women with overactive bladder [PDF]

Investigative and Clinical Urology, 2018
Purpose: In this study, we aimed to explain the role of oxidative stress in women with overactive bladder (OAB) by investigating the levels of 8-hydroxy-2′-deoxyguanosine (8-OHdG), a marker of oxidative DNA damage, and malondialdehyde (MDA), an indicator
Eda Dokumacioglu, Ozay Demiray, Ali Dokumacioglu, Arzu Sahin, Tugba Mazlum Sen, Soner Cankaya   +5 more
doaj   +2 more sources

Erzhiwan Ameliorates Restraint Stress- and Monobenzone-Induced Depigmentation in Mice by Inhibiting Macrophage Migration Inhibitory Factor and 8-Hydroxy-2-Deoxyguanosine [PDF]

Clinical, Cosmetic and Investigational Dermatology
Nan Tang,1,* Xiao-Ting Liu,2,* Xiao-Li Lin,2 Wen-Xiu Yang,2 Qi-Lin Li,3 Guo-En Wang,2 Yan-Hua Wu1 1Departments of Traditional Chinese Medicine, Guangzhou Red Cross Hospital, Jinan University, Guangzhou, Guangdong, 510220, People’s Republic of ...
Tang N, Liu XT, Lin XL, Yang WX, Li QL, Wang GE, Wu YH   +6 more
doaj   +2 more sources