Analytics of oxidative stress markers in the early diagnosis of oxygen DNA damage [PDF]
, 2017 Under homeostatic conditions, an equilibrium state between amounts of free radicals formed and their scavenging is observed. Free radicals are destructive only when present in excess.
Dabrowska, Natalia, Wiczkowski, Andrzej
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Oxidative Stress Markers (8-Isoprostane and 8-Hydroxy-2-Deoxyguanosine) in Major Depression: A Case-Control Study [PDF]
Journal of Clinical and Diagnostic Research, 2021 Introduction: Depression is associated with activation of innate immune response leading to oxidative damage. The 8-Isoprostanes and 8-hydroxy-2-deoxyguanosine (8-OHdG) are biomarkers of oxidative damage to lipids and Deoxyribonucleic Acid (DNA ...
Parul Chopra +2 more
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Age- and sun exposure-dependent differences in 8-hydroxy-2'-deoxyguanosine and Nε-(carboxymethyl)lysine in human epidermis [PDF]
, 2011 Aging and exposure to sunlight are two major factors in the deterioration of skin function. In this study, thirty-six fixed human skin samples from sun-exposed and unexposed areas from young and old individuals were used to evaluate the localization of ...
Akatsuka, Shinya +8 more
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Dehydroepiandrosterone modulates oxidative DNA damage in pancreatic cancer: A case–control study
JGH Open, 2021 Background and Aim Dehydroepiandrosterone (DHEA) has a protective role against several types of cancer, although its mechanisms of action are still unknown, it may be related to the antioxidant effect of DHEA.
Hamid Reza Fazli +4 more
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Metal nanoparticle-induced micronuclei and oxidative DNA damage in mice [PDF]
, 2012 Several mechanisms regarding the adverse health effects of nanomaterials have been proposed. Among them, oxidative stress is considered to be one of the most important. Many in vitro studies have shown that nanoparticles generate reactive oxygen species,
Kasai, Hiroshi +3 more
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8-Hydroxy-2′-deoxyguanosine expression predicts hepatocellular carcinoma outcome
Oncology Letters, 2011 Hepatocellular carcinoma (HCC) is characterized by increased oxidative stress and the production of 8-hydroxy-2'-deoxyguanosine (8-OHdG), which is one of the main mutagenic modifications of DNA by oxidative stress. We analyzed the association of 8-OHdG with post-operative survival and revealed that low levels of 8-OHdG are associated with significantly
Shengmian, Li +7 more
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Early-life adversity accelerates cellular ageing and affects adult inflammation: experimental evidence from the European starling [PDF]
, 2017 Early-life adversity is associated with accelerated cellular ageing during development and increased inflammation during adulthood. However, human studies can only establish correlation, not causation, and existing experimental animal approaches alter ...
Andrews, Clare +8 more
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Effect of Pycnogenol® on attention-deficit hyperactivity disorder (ADHD) : study protocol for a randomised controlled trial [PDF]
, 2017 Background: Methylphenidate (MPH), the first choice medication for attention-deficit hyperactivity disorder (ADHD), is associated with serious adverse effects like arrhythmia.
Ceulemans, Berten +7 more
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Urine 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG), a specific marker of oxidative stress, using direct, isocratic LC–MS/MS : method evaluation and application in study of biological variation in healthy adults [PDF]
, 2014 2009-2010 > Academic research: refereed > Publication in refereed journalAccepted ...
Benzie, IFF, Chung, WY, Lee, KF
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8-Hydroxy-2-Deoxyguanosine Levels and Cardiovascular Disease: A Systematic Review and Meta-Analysis of the Literature [PDF]
, 2016 Significance: 8-Hydroxy-2-deoxyguanosine (8-OHdG) is generated after the repair of ROS-mediated DNA damages and, thus, is one of the most widely recognized biomarkers of oxidative damage of DNA because guanosine is the most oxidized among the DNA ...
Cavalca, Viviana +6 more
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