Results 81 to 90 of about 23,792 (254)

Exploiting Pharmacokinetic/Pharmacodynamic Methods for Optimizing and Accelerating Drug Development of Innovative Anti‐Infectives

open access: yesChemMedChem, Volume 21, Issue 2, January 2026.
This article focuses on the interplay of absorbed, distributed, metabolized, and excreted (ADME) properties; in vivo pharmacokinetics (PK); and pharmacodynamics (PD) supported by in silico PK/PD modeling techniques to improve drug development by acceleration of processes and reducing attrition risks.
Katharina Rox
wiley   +1 more source

Karyotyping and Distribution Patterns of Endemic Chinese Lilies: Insights Into Their Conservation Under Climate Change

open access: yesEcology and Evolution, Volume 16, Issue 1, January 2026.
This study integrates cytogenetic and ecological analyses of two endemic Chinese alpine lilies, Lilium lophophorum (2n = 24) and L. nanum (2n = 48), to establish a foundational understanding of their chromosomal diversity and distribution patterns. We document substantial intraspecific karyotypic variation in diploid L.
Tengfei Gui   +5 more
wiley   +1 more source

Correlated growth of organic material tris (8-hydroxyquinoline) aluminum (Alq3) and its relation to optical properties [PDF]

open access: yes, 2009
We report slow correlated growth mode in energetic cluster vapor deposited organic light emissive material tris(8-hydroxyquinoline) aluminum from 5 to 100 nm.
Aurongzeb, Deeder   +2 more
core   +2 more sources

Hedysarum langranii sp. nov. (Fabaceae, Hedysareae), a New Species From China, and Supplementary Descriptions of H. smithianum and H. dentatoalatum

open access: yesEcology and Evolution, Volume 16, Issue 1, January 2026.
Hedysarum langranii sp. nov. (Fabaceae, Hedysareae) is described from China based on morphological and phylogenetic evidence. Supplementary morphological descriptions of H. smithianum and H. dentatoalatum are provided. ABSTRACT Hedysarum langranii sp. nov. (Fabaceae, Hedysareae) is described and illustrated from Shaanxi, Henan and Gansu, China.
Pei‐Liang Liu   +5 more
wiley   +1 more source

Selective Dendritic Fluorescent Sensors for Zn(II)

open access: yesMolecules, 2008
A series of dendritic 8-hydroxyquinoline (8-HQ) and 5-dialkyl(aryl)aminomethyl-8-HQ derivatives were synthesized and their fluoroionophoric properties towardrepresentative alkali, alkaline earth, group IIIA and transition metal ions ...
Yaowu Sha, Ruogu Peng, Feng Wang
doaj   +1 more source

Revised phylogeny of the Inula complex group (Asteraceae: Inuleae) with a recircumscription of Carpesium and establishment of a new genus Cladocarpesium

open access: yesJournal of Systematics and Evolution, Volume 64, Issue 1, Page 95-105, January 2026.
Cladocarpesium T. Deng & Qun Liu, gen. nov. (separated from Carpesium) is established with Cladocarpesium abrotanoides (L.) T. Deng & Qun Liu designated as the type species. The new genus is morphologically distinguished from Carpesium s.str. by its sympodial growth form (typically producing three branches), sessile capitula, and three‐seriate ...
Qun Liu   +8 more
wiley   +1 more source

Investigation of the substituent effect on the excited- state intramolecular proton transfer of 8-hydroxyquinoline

open access: yesResults in Chemistry
Fluorescent sensors operating on the excited-state intramolecular proton transfer (ESIPT) mechanism have demonstrated excellent sensing performance owing to their attributes such as large Stokes shifts and excellent photostability.
Gulimire Yaermaimaiti   +6 more
doaj   +1 more source

Crystal structure of methyl (E)-4-[2-(8-hydroxyquinolin-2-yl)vinyl]benzoate

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2016
The title compound, C19H15NO3, was synthesized by a Perkin reaction of 2-methyl-8-hydroxyquinoline and 4-formyl-2-methylbenzoate in acetic anhydride under a nitrogen atmosphere.
Yu-Xing Xu, Wei-Ji Hu, Guo-Liang Zhao
doaj   +1 more source

Generation and plant production of recombinant fluorescent immunoglobulin G as innovative immunodiagnostic reagents

open access: yesPlant Biotechnology Journal, Volume 24, Issue 1, Page 300-312, January 2026.
Summary Immunodiagnostic systems for on‐site screening are increasingly in demand but require expensive reagents such as chemically modified antibodies. To obtain biomolecules as ready‐to‐use reagents for diagnostics, new recombinant fluorescent immunoglobulins G were generated by fusion of the heavy chain of a monoclonal antibody, 5H3, to two ...
Ramona Sterpa   +5 more
wiley   +1 more source

High-throughput screening with the Eimeria tenella CDC2-related kinase2/cyclin complex EtCRK2/EtCYC3a [PDF]

open access: yes, 2012
The poultry disease coccidiosis, caused by infection with Eimeria spp. apicomplexan parasites, is responsible for enormous economic losses to the global poultry industry.
Aziz   +12 more
core   +1 more source

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