Results 91 to 100 of about 1,652 (188)

Kushenol A and 8-prenylkaempferol, tyrosinase inhibitors, derived from Sophora flavescens

Journal of Enzyme Inhibition and Medicinal Chemistry, 2018
Tyrosinase is known for an enzyme that plays a key role in producing the initial precursor of melanin biosynthesis. Inhibition of the catalytic reaction of this enzyme led to some advantage such as skin-whitening and anti-insect agents. To find a natural
Jang Hoon Kim, In Sook Cho, Yang Kang So, Hyeong-Hwan Kim, Young Ho Kim   +4 more
doaj   +1 more source

Adipocyte maturation impacts daunorubicin disposition and metabolism

European Journal of Clinical Investigation, Volume 54, Issue 12, December 2024.
Obesity is associated with higher risk for chemoresistance in paediatric acute lymphoblastic leukaemia. Increased adipocyte differentiation correlated with increase daunorubicin sequestration and metabolism were found in the expanding fat tissue. Increased expression and metabolic capacity of aldo‐keto reductase and carbonyl reductase isoenzymes were ...
Zeyang Li, Rachael Ngu, Aditya Anil Naik, Kaitlyn Trinh, Vladislava Paharkova, Hanyue Liao, Yulu Liu, Cindy Zhuang, Danh Le, Hua Pei, Isaac Asante, Steven D. Mittelman, Stan Louie   +12 more
wiley   +1 more source

Excessive levels of diverse phytoestrogens can modulate steroidogenesis and cell migration of KGN human granulosa-derived tumor cells

Toxicology Reports, 2014
Phytoestrogens are plant-derived estrogen-like compounds that are increasingly used for their suggested health promoting properties, even by healthy, young women.
Kamila A. Solak, Fiona M.J. Wijnolts, Sandra M. Nijmeijer, Bas J. Blaauboer, Martin van den Berg, Majorie B.M. van Duursen   +5 more
doaj   +1 more source

Tissue distribution and pharmacokinetics of isoxanthohumol from hops in rodents [PDF]

, 2023
Vegetables and fruits contain prenylflavonoids with biological functions that might improve human health. The prenylflavonoid isoxanthohumol (IXA) and its derivative, 8-prenylnaringenin (8-PN), have beneficial activities, including anti-cancer effects ...
203812/profile-ja.html, 410, 90547978, Hata, Natsumi, Mukai, Rie, ムカイ, リエ, 向井, 理恵   +6 more
core  

Humulus lupulus L.: Evaluation of Phytochemical Profile and Activation of Bitter Taste Receptors to Regulate Appetite and Satiety in Intestinal Secretin Tumor Cell Line (STC‐1 Cells)

Molecular Nutrition &Food Research, Volume 68, Issue 21, November 2024.
Hop inflorescence extract causes the release of anorexigenic hormones from intestinal secretin tumor cell line (STC‐1). This effect is due to the interaction with bitter receptors resulting in the activation of mediators involved in the signal transduction process in a mechanism dependent on intracellular calcium. Scope Inflorescences of the female hop
Ludovica Lela, Vittorio Carlucci, Chrissa Kioussi, Jaewoo Choi, Jan F. Stevens, Luigi Milella, Daniela Russo   +6 more
wiley   +1 more source

The Hop Polyphenols Xanthohumol and 8-Prenyl-Naringenin Antagonize the Estrogenic Effects of Fusarium Mycotoxins in Human Endometrial Cancer Cells

Frontiers in Nutrition, 2018
The Fusarium toxin zearalenone (ZEN) and its reductive metabolite α-zearalenol (α-ZEL) are well-documented endocrine disruptors that are frequently found to contaminate cereal products, including beer.
Georg Aichinger, Julia Beisl, Doris Marko   +2 more
doaj   +1 more source

Overview of air pollution and endocrine disorders [PDF]

, 2018
Over recent years, many environmental pollutant chemicals have been shown to possess the ability to interfere in the functioning of the endocrine system and have been termed endocrine disrupting chemicals. These compounds exist in air as volatile or semi-
Darbre, Philippa D.
core   +2 more sources

Soybean extract inhibits influenza virus entry: Mechanistic insights

Food Science &Nutrition, Volume 12, Issue 10, Page 7671-7682, October 2024.
Our study revealed an effect on entry within the antiviral properties of soybean extract. We found that the inhibition of viral entry by soybean extract was an inhibition of clathrin‐dependent endocytosis. Abstract Influenza viruses pose significant public health threats because they can cause seasonal outbreaks and global pandemics. Current preventive
Natsumi Sakata, Yuka Horio, Ryoichi Yamaji, Yuji Isegawa   +3 more
wiley   +1 more source

Foliar applications of a Malvaceae‐derived protein hydrolysate and its fractions differentially modulate yield and functional traits of tomato under optimal and suboptimal nitrogen application

Journal of the Science of Food and Agriculture, Volume 104, Issue 12, Page 7603-7616, September 2024.
Abstract BACKGROUND Protein hydrolysates (PHs) can enhance plant nitrogen nutrition and improve the quality of vegetables, depending on their bioactive compounds. A tomato greenhouse experiment was conducted under both optimal (14 mM) and suboptimal (2 mM) nitrogen (N‐NO3) conditions. Tomatoes were treated with a new Malvaceae‐derived PH (MDPH) and its
Mariateresa Cardarelli, Angela Valentina Ceccarelli, Christophe El Nakhel, Youssef Rouphael, Hajar Salehi, Paola Ganugi, Leilei Zhang, Lucini Luigi, Youry Pii, Seunghyun Choi, Hye‐Ji Kim, Giuseppe Colla   +11 more
wiley   +1 more source

Toxicity and Cell Cycle Effects of Synthetic 8-Prenylnaringenin and Derivatives in Human Cells

Pharmacology, 2004
The estrogenic flavanone <i>rac</i>-8-prenylnaringenin (8-PN) and 3 derivatives (<i>rac</i>-7-(O-prenyl)naringenin-4′-acetate (7-O-PN), <i>rac</i>-5-(O-prenyl)naringenin-4′,7-diacetate (5-O-PN), and <i>rac</i>-6-(1,1-dimethylallyl)naringenin (6-DMAN) were prepared by chemical synthesis and analyzed with ...
Tokalov, Sergey V., Henker, Yvonne, Schwab, Pia, Metz, Peter, Gutzeit, Herwig O.   +4 more
openaire   +4 more sources