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Integrated network pharmacology and experimental validation to explore the mechanisms underlying naringenin treatment of chronic wounds

open access: yesScientific Reports, 2023
Naringenin is a citrus flavonoid with various biological functions and a potential therapeutic agent for skin diseases, such as UV radiation and atopic dermatitis.
Rui Sun   +11 more
doaj   +2 more sources

Naringenin Induces HepG2 Cell Apoptosis via ROS-Mediated JAK-2/STAT-3 Signaling Pathways

open access: yesMolecules, 2023
Hepatocarcinoma is one of the most prevalent digestive system tumors worldwide and lacks effective therapy. Recently, naringenin has been isolated from some citrus fruits, and its anticancer effects have been tested.
Ming Zhang   +6 more
doaj   +2 more sources

Protective Effects of Naringenin and Apigenin in Ameliorating Skin Damage via Mediating the Nrf2 and NF-κB Pathways in Mice

open access: yesFoods, 2023
Naringenin and apigenin are common flavonoids derived from edible plants with the potential to alleviate inflammation and improve skin antioxidation. This study aimed to evaluate the effects of naringenin and apigenin on oleic acid-induced skin damage in
Jie Li   +6 more
doaj   +2 more sources

Biotransformation of Naringenin by Into Three Naringenin Derivatives [PDF]

open access: yesNatural Product Communications, 2019
In this study, a whole-cell biotransformation by Bacillus amyloliquefaciens Korean Collection for Type Culture 13588 was carried out to acquire naringenin derivatives. High-performance liquid chromatography analysis of the reaction metabolites showed the
Manoj Koirala   +5 more
doaj   +2 more sources

Naringenin as a potential immunomodulator in therapeutics

open access: yesPharmacological Research, 2018
Naringenin, a citrus flavonoid that possesses various biological activities, has emerged as a potential therapeutic agent for the management of a variety of diseases. Studies using cell culture system have shown that naringenin can inhibit inflammatory response in diverse cell types.
Wenfeng Zeng, Fayun Zhang, Wei Liang
exaly   +3 more sources

Flavonoids naringenin chalcone, naringenin, dihydrotricin, and tricin are lignin monomers in papyrus [PDF]

open access: yesPlant Physiology, 2021
AbstractRecent studies demonstrate that several polyphenolic compounds produced from beyond the canonical monolignol biosynthetic pathways can behave as lignin monomers, participating in radical coupling reactions and being incorporated into lignin polymers. Here, we show various classes of flavonoids, the chalconoid naringenin chalcone, the flavanones
Jorge Rencoret   +9 more
openaire   +3 more sources

Polymeric Forms of Plant Flavonoids Obtained by Enzymatic Reactions

open access: yesMolecules, 2022
Naringenin is one of the flavonoids originating from citrus fruit. This polyphenol is mainly found in grapefruit, orange and lemon. The antioxidant and antimicrobial properties of flavonoids depend on their structure, including the polymeric form.
Malgorzata Latos-Brozio   +2 more
doaj   +1 more source

Evaluation of spasmolytic effects of naringenin on ileum contraction and intestinal charcoal meal transit: Involvement of ATP-sensitive K+ channels [PDF]

open access: yesJournal of HerbMed Pharmacology, 2022
Introduction: Naringenin is a flavonoid constituent of many herbal plants, including citreous fruits. Biological studies have suggested various therapeutic effects for naringenin, including protective effects on gastrointestinal (GI) motility.
Hassan Sadraei   +2 more
doaj   +1 more source

Naringenin inhibits lipid accumulation by activating the AMPK pathway in vivo and vitro

open access: yesFood Science and Human Wellness, 2023
The aim of this study was to explore the lipid-lowering effect of naringenin and the underlying mechanism in high-fat-diet-fed SD rats and 3T3-L1 cells. In this study, SD rats were divided into the normal chow diet group (NCD), high fat diet group (HFD),
Xiaoyu Cai   +7 more
doaj   +1 more source

Naringenin: A flavanone with anti-inflammatory and anti-infective properties.

open access: yesBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023
Although a growing body of research has recently shown how crucial inflammation and infection are to all major diseases, several of the medications currently available on the market have various unfavourable side effects, necessitating the development of
Jiong Cai   +13 more
semanticscholar   +1 more source

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