Results 41 to 50 of about 29,168 (237)

Practical Synthesis of Naringenin [PDF]

open access: yesJournal of Chemical Research, 2015
Two routes for the synthesis of the flavanone naringenin are described. In the first, 3,5-dimethoxyphenol is converted to 2-hydroxy-4,6-dimethoxyacetophenone and then by condensation with anisaldehyde to 2′-hydroxy-4,4′,6′-trimethoxychalcone. The chalcone is then cyclised with aqueous hydrochloric acid and demethylated with pyridine hydrochloride to ...
Qian Wang   +5 more
openaire   +1 more source

Naringenin alters the pharmacokinetics of ranolazine in part through the inhibition of cytochrome P450 (3A4) and P-glycoprotein

open access: yesFuture Journal of Pharmaceutical Sciences, 2023
Background This study set out to look at how naringenin affected the pharmacokinetics of ranolazine in rats. The pharmacokinetic investigation of ranolazine in rats following oral administration of ranolazine with or without coadministration of ...
Faisal Alotaibi
doaj   +1 more source

Naringenin promotes angiogenesis of ischemic myocardium after myocardial infarction through miR-223-3p/IGF1R axis

open access: yesRegenerative Therapy, 2022
Introduction: Naringenin exerts a protective effect on myocardial ischemia and reperfusion. It has been reported that miR-223-3p is a potential target for the treatment of myocardial infarction (MI).
Jinguo Fu   +6 more
doaj   +1 more source

Naringenin inhibits dendritic cell maturation and has therapeutic effects in a murine model of collagen-induced arthritis

open access: yes, 2017
The aim of this study was to investigate the effect of naringenin (5,7,4'-trihydroxyflavanone), a citrus flavonoid, on dendritic cell (DC) maturation, as well as its potential as a therapeutic agent in a murine model of collagen-induced arthritis (CIA ...
朱清良   +1 more
core   +1 more source

Antioxidant and Pro-oxidant properties of naringenin: Unveiling the biphasic impacts on model, Drosophila melanogaster

open access: yesFood Chemistry Advances
Naringenin is a dietary flavonoid that has health-promoting benefits. However, studies demonstrating the concentration-dependent effects of naringenin are still lacking.
Siddhartha Ghanty   +8 more
doaj   +1 more source

High‐Density E. Coli Cultivation Arrays for Combinatorial Drug Testing With Subsequent Lipid Profiling by MALDI‐MS

open access: yesAdvanced Science, EarlyView.
High‐throughput antibiotic cross‐gradient assays on microdroplet arrays. A multichannel printhead together with five pressure regulators forms droplet arrays of up to 20 832 droplets within 25 minutes. Each droplet contains unique concentrations of antibiotics, allowing to moniture a vast spectrum of bacterial repsonses over night. The bacterial growth
M. Breitfeld   +5 more
wiley   +1 more source

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

open access: yesAdvanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan   +5 more
wiley   +1 more source

Naringenin prevents cholesterol-induced systemic inflammation, metabolic dysregulation, and atherosclerosis in Ldlr−/− mice[S]

open access: yesJournal of Lipid Research, 2013
Obesity-associated chronic inflammation contributes to metabolic dysfunction and propagates atherosclerosis. Recent evidence suggests that increased dietary cholesterol exacerbates inflammation in adipose tissue and liver, contributing to the ...
Julia M. Assini   +9 more
doaj   +1 more source

Effects of naringenin on the pharmacokinetics of tofacitinib in rats [PDF]

open access: yesPharmaceutical Biology, 2020
Context: Naringenin and tofacitinib are often used together for treatment of rheumatoid arthritis in Chinese clinics.Objective: This experiment investigates the effect of naringenin on the pharmacokinetics of tofacitinib in rats.Materials and methods: Twelve Sprague-Dawley rats were randomly divided into two groups (experimental group and control group)
Bo Wang   +7 more
openaire   +3 more sources

Potensi Kombinasi Naringenin-Liposom Sebagai Anti-Viral dan Anti-Fibrotik dalam Penatalaksanaan Hepatitis C

open access: yesJurnal Kesehatan Andalas, 2020
Penatalaksanaan hepatitis C yang umum diberikan di Indonesia adalah terapi kombinasi Peg-IFNα dan RBV, namun terapi tersebut mempunyai efek samping seperti depresi, hipotiroidisme, memperlambat motorik, risiko kardiovaskular tinggi, dan lain sebagainya ...
Ida AyuWidya Anjani   +5 more
doaj   +1 more source

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