Results 61 to 70 of about 48,291 (295)

Effects of naringenin on the pharmacokinetics of tofacitinib in rats [PDF]

Pharmaceutical Biology, 2020
Context: Naringenin and tofacitinib are often used together for treatment of rheumatoid arthritis in Chinese clinics.Objective: This experiment investigates the effect of naringenin on the pharmacokinetics of tofacitinib in rats.Materials and methods: Twelve Sprague-Dawley rats were randomly divided into two groups (experimental group and control group)
Bo Wang, Jiquan Shen, Quan Zhou, Deru Meng, Youwu He, Feifei Chen, Shuanghu Wang, Weiping Ji   +7 more
openaire   +3 more sources

Chemical profiling of infusions and decoctions of Helichrysum italicum subsp picardii by UHPLC-PDA-MS and in vitro biological activities comparatively with green tea (Camellia sinensis) and rooibos tisane (Aspalathus linearis) [PDF]

, 2017
Several medicinal plants are currently used by the food industry as functional additives, for example botanical extracts in herbal drinks. Moreover, the scientific community has recently begun focusing on halophytes as sources of functional beverages ...
Barreira, Luísa, Bijttebier, Sebastiaan, Custódio, Luísa, J. C. or Varela J. or Varela J.C.S., Varela, Neves, Vanessa, Pereira, Catarina Guerreiro, Pieters, Luc, Rivas, Ricardo, Rodrigues, Maria João   +8 more
core   +1 more source

Promotion of ROS-mediated apoptosis, G2/M arrest, and autophagy by naringenin in non-small cell lung cancer

International Journal on Biological Sciences
Background: As lung cancer is the leading cause of cancer death worldwide, the development of new medicines is a crucial endeavor. Naringenin, a flavanone derivative, possesses anti-cancer and anti-inflammatory properties and has been reported to have ...
Tsung-Ming Chang, Miao-Ching Chi, Y. Chiang, Chieh-Mo Lin, Mei-Ling Fang, Chiang-Wen Lee, Ju-Fang Liu, Yu Ru Kou   +7 more
semanticscholar   +1 more source

Naringenin alters the pharmacokinetics of ranolazine in part through the inhibition of cytochrome P450 (3A4) and P-glycoprotein

Future Journal of Pharmaceutical Sciences, 2023
Background This study set out to look at how naringenin affected the pharmacokinetics of ranolazine in rats. The pharmacokinetic investigation of ranolazine in rats following oral administration of ranolazine with or without coadministration of ...
Faisal Alotaibi
doaj   +1 more source

A Scoping Review of the Skeletal Effects of Naringenin

Nutrients, 2022
Background: Osteoporosis is caused by the deterioration of bone density and microstructure, resulting in increased fracture risk. It transpires due to an imbalanced skeletal remodelling process favouring bone resorption. Various natural compounds can positively influence the skeletal remodelling process, of which naringenin is a candidate.
Muhamed Lahtif Nor Muhamad, Sophia Ogechi Ekeuku, Sok-Kuan Wong, Kok-Yong Chin   +3 more
openaire   +2 more sources

Naringin and Naringenin Polyphenols in Neurological Diseases: Understandings from a Therapeutic Viewpoint

Life, 2022
The glycosides of two flavonoids, naringin and naringenin, are found in various citrus fruits, bergamots, tomatoes, and other fruits. These phytochemicals are associated with multiple biological functions, including neuroprotective, antioxidant ...
T. Emran, F. Islam, Nikhil Nath, Hriday Sutradhar, Rajib Das, Saikat Mitra, M. Alshahrani, A. Alhasaniah, Rohit Kumar Sharma   +8 more
semanticscholar   +1 more source

Identification of plasma and urinary metabolites and catabolites derived from orange juice (poly)phenols: analysis by high-performance liquid chromatography–high-resolution mass spectrometry [PDF]

, 2016
Orange juice is a rich source of (poly)phenols, in particular, the flavanones hesperetin-7-O-rutinoside and naringenin-7-O-rutinoside. Following the acute consumption of 500 mL of orange juice containing 398 μmol of (poly)phenols by 12 volunteers, 0–24 h
Ada García, Alan Crozier, Dalia Malkova, Gee J. M., Gema Pereira-Caro, Hengstmann J. H., Iziar A. Ludwig, José Manuel Moreno-Rojas, McCullough M. L., Palli D., Thelma Polyviou   +10 more
core   +1 more source

Therapeutic activities of naringenin on efavirenz-induced sleep-like disorder in the midbrain of white albino mice [PDF]

Iranian Journal of Basic Medical Sciences, 2020
Objective(s): Efavirenz, has proven to be effective in suppressing human immunodeficiency virus (HIV) viral load; however, complaints of sleep disorders including hallucination, and insomnia have greatly contributed to non-adherence to antiretroviral ...
Olufunke Dosumu, Edidiong Akang, Oluwatomisin Faniyan, Alani Akanmu   +3 more
doaj   +1 more source

Naringenin Alleviates Renal Ischemia Reperfusion Injury by Suppressing ER Stress-Induced Pyroptosis and Apoptosis through Activating Nrf2/HO-1 Signaling Pathway

Oxidative Medicine and Cellular Longevity, 2022
Endoplasmic reticulum (ER) stress, pyroptosis, and apoptosis are critical molecular events in the occurrence and progress of renal ischemia reperfusion (I/R) injury.
Banghua Zhang, S. Wan, Hao Liu, Q. Qiu, Hui Chen, Zhiyuan Chen, Lei Wang, Xiuheng Liu   +7 more
semanticscholar   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source