Results 11 to 20 of about 48,291 (295)

Antimicrobial Activity of Quercetin, Naringenin and Catechin: Flavonoids Inhibit Staphylococcus aureus-Induced Hemolysis and Modify Membranes of Bacteria and Erythrocytes

Molecules, 2023
Search for novel antimicrobial agents, including plant-derived flavonoids, and evaluation of the mechanisms of their antibacterial activities are pivotal objectives.
A. Veiko, Ewa Olchowik-Grabarek, Szymon Sekowski, Anna Roszkowska, E. Lapshina, I. Dobrzyńska, M. Zamaraeva, I. Zavodnik   +7 more
semanticscholar   +1 more source

Optimum flux rerouting for efficient production of naringenin from acetate in engineered Escherichia coli

Biotechnology for Biofuels and Bioproducts, 2022
Background Microbial production of naringenin has received much attention owing to its pharmaceutical applicability and potential as a key molecular scaffold for various flavonoids.
Dong Hwan Kim, Hyun Gyu Hwang, Gyoo Yeol Jung   +2 more
doaj   +1 more source

Naringin and Naringenin: Their Mechanisms of Action and the Potential Anticancer Activities

Biomedicines, 2022
Naringin and naringenin are the main bioactive polyphenols in citrus fruits, the consumption of which is beneficial for human health and has been practiced since ancient times.
J. Stabrauskienė, D. Kopustinskiene, Robertas Lažauskas, J. Bernatonienė   +3 more
semanticscholar   +1 more source

Pharmacokinetic Comparisons of Naringenin and Naringenin-Nicotinamide Cocrystal in Rats by LC-MS/MS [PDF]

Journal of Analytical Methods in Chemistry, 2020
Naringenin (NAR), 4′,5,7-trihydroxydihydroflavone, has a wide range of pharmacological activities but shows poor water solubility and low bioavailability. The pharmacokinetics and bioavailability of naringenin-nicotinamide cocrystal (NAR-NCT), which offers improved solubility, were evaluated in this study.
Dan Xu, Gui-Qiu Zhang, Ting-Ting Zhang, Bo Jin, Chen Ma   +4 more
openaire   +3 more sources

Characterization, in Vitro and in Vivo Evaluation of Naringenin-Hydroxypropyl-β-Cyclodextrin Inclusion for Pulmonary Delivery

Molecules, 2020
Naringenin, a flavonoid compound which exists abundantly in Citrus fruits, is proven to possess excellent antitussive and expectorant effects. However, the clinical applications of naringenin are restricted by its poor solubility and low local ...
Minyi Guan, Rui Shi, Yuying Zheng, Xuan Zeng, Weiyang Fan, Yonggang Wang, Weiwei Su   +6 more
doaj   +1 more source

Naringenin ameliorates collagen‐induced arthritis through activating AMPK‐mediated autophagy in macrophages

Immunity, Inflammation and Disease, 2023
Background Naringenin is widely recognized for its notable attributes, including anti‐inflammatory, anti‐cancer, and immunomodulatory activities. However, its specific implications for rheumatoid arthritis (RA) and the underlying mechanisms remain to be ...
Wei Zhang, Yuan Zhang, Jianguang Zhang, Chunbiao Deng, Chao Zhang   +4 more
doaj   +1 more source

Naringenin and Hesperidin as Promising Alternatives for Prevention and Co-Adjuvant Therapy for Breast Cancer

Antioxidants, 2023
Citrus (genus Citrus L.) fruits are essential sources of bioactive compounds with antioxidant properties, such as flavonoids. These polyphenolic compounds are divided into subclasses, in which flavanones are the most prominent. Among them, naringenin and
Maria Beatriz Madureira, Vírgínia Concato, E. M. S. Cruz, Juliana Maria Bitencourt de Morais, F. S. Inoue, Natália Concimo Santos, Manoela Daniele Gonçalves, Milena Cremer de Souza, Thalita Basso Scandolara, Mariane Fontana Mezoni, Murilo Galvani, Fábio Rodrigues Ferreira Seiva, C. Panis, M. M. Miranda-Sapla, W. Pavanelli   +14 more
semanticscholar   +1 more source

Grapefruit Flavonoid Naringenin Sex-Dependently Modulates Action Potential in an In Silico Human Ventricular Cardiomyocyte Model

Antioxidants, 2022
Recent in vitro studies showed that grapefruit (Citrus × paradisi) flavonoid naringenin alters the function of cardiac ion channels. Here, we explored the effect of naringenin on cardiomyocyte action potentials (APs) using a detailed in silico model of ...
Henry Sutanto, Decsa Medika Hertanto, Hendri Susilo, Citrawati Dyah Kencono Wungu   +3 more
doaj   +1 more source

Fine-tuning of p-coumaric acid synthesis to increase (2S)-naringenin production in yeast.

Metabolic Engineering, 2023
(2S)-Naringenin is a key precursor for biosynthesis of various high-value flavonoids and possesses a variety of nutritional and pharmaceutical properties on human health.
Jiwei Mao, Marta Tous Mohedano, Jingjuan Fu, Xiaowei Li, Quanli Liu, Jens Ø J. Nielsen, V. Siewers, Yun Chen   +7 more
semanticscholar   +1 more source

Naringenin and Its Derivatives—Health-Promoting Phytobiotic against Resistant Bacteria and Fungi in Humans

Antibiotics, 2022
Naringenin is a trihydroxyflavanone present in large amount in different citrus fruits, e.g., oranges, pomelos, grapefruits, but also in tomatoes, fenugreek and coffee.
Anna Duda-Madej, Jakub Stecko, Jakub Sobieraj, Natalia Szymańska, J. Kozłowska   +4 more
semanticscholar   +1 more source