Activation of proestrogens from hops by human intestinal bacteria: conversion of isoxanthohumol into the potent phytoestrogen 8-prenylnaringenin [PDF]
, 2007 Hop, an essential ingredient in beer, contains different prenylflavonoids, among which 8-prenylnaringenin (8-PN) would be the most potent phytoestrogen currently known.
Possemiers, Sam
core +1 more source
Investigation of molecular interactions of prenylflavonoids at GABAA receptor subtypes [PDF]
, 2019 Prenylated flavonoids derived from Hops (Humulus lupulus) activate the γ-aminobutyric acid (GABA) type A receptors through positive and negative modulation.
Somborac, Tamara
core
CoastsEmerging pollutants, like phytoestrogens, are gaining attention in the scientific community for their impact on aquatic organisms. Nevertheless, there is a paucity of studies examining their effects on tropical aquatic species.
Luciana Lopes Guimarães +7 more
doaj +1 more source
Journal for ImmunoTherapy of CancerBackground Cervical cancer remains a global health challenge. The identification of new immunotherapeutic targets may provide a promising platform for advancing cervical cancer treatment.Objective This study aims to investigate the role of CUB domain ...
Jie Li +18 more
doaj +1 more source
ROLE OF PHYTOESTROGENS IN PREVENTION OF OSTEOPOROSIS [PDF]
, 2015 Osteoporosis is a disease characterized with the disbalance between the bone-building activity of osteoblasts and the re absorptive activity of osteoclasts.
Pankova, Stefka, Tsvetkova, Dobrina
core
Estrogen Receptor-Beta Dependent Activities of Dietary Compounds in a Genetically Modified Rat Raphe Nuclei-Derived Cell Line [PDF]
, 2011 Estrogens greatly affect the activity and connectivity of serotonergic neural cell populations, which extend from clusters of nuclei in the brainstem, termed the raphe nuclei, where estrogen receptor β is the most abundantly expressed estrogen receptor ...
Amer, Dena Ahmed Mohamed
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Nature’s brewery to bedtime: The Role of hops in GABAA receptor modulation and sleep promotion [PDF]
Insomnia, a prevalent health challenge, often requires pharmacological interventions to improve sleep onset, maintenance, and quality. Benzodiazepines and Z-drugs, like other positive modulators, enhance the inhibitory effects of gamma-aminobutyric acid (
Benkherouf, Ali Yasser
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Xanthohumol and 8-prenylnaringenin reduce type 2 diabetes-associated oxidative stress by downregulating galectin-3. [PDF]
Porto Biomed J, 2019 Luís C +8 more
europepmc +1 more source
8-Prenylnaringenin suppresses obesity in high-fat diet-fed C57BL/6J mice via adiponectin secretion. [PDF]
J Clin Biochem NutrOkada F +5 more
europepmc +1 more source