Major Bioactive Prenylated Flavonoids from Humulus lupulus L., Their Applications in Human Diseases and Structure-Activity Relationships (SAR) – A Review [PDF]
Pharmaceutical SciencesIn recent years, the incidence of cancers, inflammatory diseases, Alzheimer’s disease, glucose metabolism disorder and diabetes has increased alarmingly which demands more research into the discovery of new drug candidates to treat these human diseases ...
Ferah Comert Onder +9 more
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The HMI™ module: a new tool to study the host-microbiota interaction in the human gastrointestinal tract in vitro [PDF]
, 2014 Background: Recent scientific developments have shed more light on the importance of the host-microbe interaction, particularly in the gut. However, the mechanistic study of the host-microbe interplay is complicated by the intrinsic limitations in ...
Bracke, Marc +13 more
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Foods, 2021 Xanthohumol (XN), isoxanthohumol (IX) and 8-prenylnaringenin (8-PN) are important prenylflavonoids present in hops with potential beneficial properties.
Jelena B. Golubović +6 more
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Could Hop-derived Bitter Compounds Improve Glucose Homeostasis by Stimulating the Secretion of GLP-1? [PDF]
, 2019 Hops (Humulus lupulus L.) is by far the greatest contributors to the bitter property of beer. Over the past years, a large body of evidence demonstrated the presence of taste receptors in different locations of the oral cavity.
Annunziata, Giuseppe +6 more
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Chemical screening identifies the β-Carboline alkaloid harmine to be synergistically lethal with doxorubicin. [PDF]
, 2017 Despite being an invaluable chemotherapeutic agent for several types of cancer, the clinical utility of doxorubicin is hampered by its age-related and dose-dependent cardiotoxicity.
Ashour, M.E. +4 more
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Prenylated Flavonoids as Valuable Biologically Active Compounds from Hops
Kvasný průmysl, 2017 Hop cones contain a number of important compounds, which are frequently used in the brewing industry. Recently, an increasing interest has been raised in using hops also for other purposes, particularly in the pharmaceutical industry.
Jan Nešpor +4 more
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Chlorella vulgaris biomass enriched by biosorption of polyphenols [PDF]
, 2015 Cell walls of microalgae are variable and contain non-specific domains where different molecules can bind. The enrichment of microalgal biomass with nutrients through adsorption can be an interesting process for the food and feed industry. In this study,
Alvarez-Parrilla +40 more
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Antioxidants, 2023 Chronic neurodegenerative diseases are typically associated with oxidative stress conditions leading to neuronal cell death. We aimed to investigate the neuroprotective effect of three pyranocoumarins (decursin, decursinol angelate, and decursinol ...
Nguyen Khoi Song Tran +5 more
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Arsenic thiolation and the role of sulfate-reducing bacteria from the human intestinal tract [PDF]
, 2014 BACKGROUND: Arsenic (As) toxicity is primarily based on its chemical speciation. Although inorganic and methylated As species are well characterized in terms of metabolism and formation in the human body, the origin of thiolated methylarsenicals is still
Alava, Pradeep +4 more
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Flavonoids as Phytoestrogenic Components of Hops and Beer
Molecules, 2020 The value of hops (Humulus lupulus L.) in beer production has been undisputed for centuries. Hops is rich in humulones and lupulones which gives the characteristic aroma and bitter taste, and preserves this golden drink against growing bacteria and molds.
Tomasz Tronina +2 more
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