Results 1 to 10 of about 987,996 (285)

Sensorimotor Gating Impairments Induced by MK-801 Treatment may be Reduced by Tolerance Effect and by Familiarization in Monkeys [PDF]

open access: yesFrontiers in Pharmacology, 2015
Dizocilpine (MK-801) is a noncompetitive NMDA antagonist that induces schizophrenic-like effects. It is therefore widely used in experimental models of schizophrenia including prepulse inhibition (PPI) impairments in rodents.
Patricia G Saletti   +5 more
doaj   +5 more sources

Stromal Cell-Derived Factor 1 Polymorphism in Retinal Vein Occlusion. [PDF]

open access: yesPLoS ONE, 2016
Stromal cell-derived factor 1 (SDF1) has crucial role in the regulation of angiogenesis and ocular neovascularisation (NV). The purpose of this study was to evaluate the association between SDF1-3'G(801)A polymorphism and NV complications of retinal vein
Andrea Szigeti   +7 more
doaj   +7 more sources

Synthesis of Defective MOF-801 via Air–Liquid Segmented Flow for Catalytic Transfer Hydrogenation of Furfural [PDF]

open access: yesMolecules
As one of the most important platform chemicals, furfural (FAL) can be converted into high-value-added products such as furfuryl alcohol (FOL) through multiple pathways.
Yuxuan Liu   +8 more
doaj   +2 more sources

Functional ultrasound imaging and prewhitening analysis reveal MK-801-induced disruption of brain network connectivity [PDF]

open access: yesFrontiers in Pharmacology
BackgroundDisruption of N-methyl-D-aspartate receptor (NMDAR) activity within the septohippocampal network - a critical circuit that includes the hippocampus, medial prefrontal cortex (mPFC) and other nuclei - is believed to contribute to learning and ...
Erik Hakopian   +19 more
doaj   +2 more sources

Effect of single subconjunctival injection of bevacizumab on primary pterygium: clinical, histopathological and immunohistochemical study [PDF]

open access: yesInternational Journal of Ophthalmology, 2018
AIM: To evaluate the effect (clinically, histopathologically and immunohistochemically) and safety of a single intra-pterygium injection of bevacizumab.
Tarek A Mohamed   +3 more
doaj   +1 more source

SKI‐G‐801, an AXL kinase inhibitor, blocks metastasis through inducing anti‐tumor immune responses and potentiates anti‐PD‐1 therapy in mouse cancer models

open access: yesClinical & Translational Immunology, 2022
Objectives AXL‐mediated activation of aberrant tyrosine kinase drives various oncogenic processes and facilitates an immunosuppressive microenvironment.
Chun‐Bong Synn   +33 more
doaj   +1 more source

Effect of the glucocorticoid receptor antagonist RU486 on MK-801 induced behavioural sensitisation. [PDF]

open access: yesPLoS ONE, 2017
Stress is known to modulate sensitisation to repeated psychostimulant exposure. However, there is no direct evidence linking glucocorticoids and sensitisation achieved by repeated administration of the NMDA receptor antagonist MK-801.
Emilia M Lefevre   +5 more
doaj   +1 more source

Resveratrol, a SIRT1 Activator, Ameliorates MK-801-Induced Cognitive and Motor Impairments in a Neonatal Rat Model of Schizophrenia

open access: yesFrontiers in Psychiatry, 2020
BackgroundIn neonatal rats, MK-801 treatment generates schizophrenia-like symptoms. Resveratrol (RSV) is a phenolic compound and a potent neuroprotective agent.
Juan Niu, Yuquan Cao, Yongjuan Ji
doaj   +1 more source

Enhanced atmospheric water harvesting efficiency through green-synthesized MOF-801: a comparative study with solvothermal synthesis

open access: yesScientific Reports, 2023
Adsorption-based atmospheric water harvesting has emerged as a compelling solution in response to growing global water demand. In this context, Metal–organic frameworks (MOFs) have garnered considerable interest due to their unique structure and ...
Mohammad Aghajani Hashjin   +3 more
doaj   +1 more source

Behavioral features and disorganization of oscillatory activity in C57BL/6J mice after acute low dose MK-801 administration

open access: yesFrontiers in Neuroscience, 2022
Low dose acute administration of N-methyl-D-aspartate receptor (NMDAR) antagonist MK-801 is widely used to model cognition impairments associated with schizophrenia (CIAS) in rodents. However, due to no unified standards for animal strain, dose, route of
Keke Cui   +15 more
doaj   +1 more source

Home - About - Disclaimer - Privacy