Results 1 to 10 of about 173,591 (312)

Hydrogen Gas Therapy in Schizophrenia: Potential Neuroprotective Effects From an Animal Study [PDF]

Neuropsychopharmacology Reports
Aims Oxidative stress has recently emerged as a key factor in the pathophysiology of schizophrenia. This study investigated whether inhalation therapy with hydrogen gas, a selective antioxidant, could reduce oxidative stress and improve behavioral ...
Nobumi Miyake, Toshiaki Haga, Shin‐Ichi Hirano, Yusuke Ichikawa, Yoshiyo Oguchi, Kumiko Ando   +5 more
doaj   +2 more sources

Effect of single subconjunctival injection of bevacizumab on primary pterygium: clinical, histopathological and immunohistochemical study [PDF]

International Journal of Ophthalmology, 2018
AIM: To evaluate the effect (clinically, histopathologically and immunohistochemically) and safety of a single intra-pterygium injection of bevacizumab.
Tarek A Mohamed, Wael Soliman, Ahmed M. Fathalla, Abeer El Refaie   +3 more
doaj   +1 more source

Stromal Cell-Derived Factor 1 Polymorphism in Retinal Vein Occlusion. [PDF]

PLoS ONE, 2016
Stromal cell-derived factor 1 (SDF1) has crucial role in the regulation of angiogenesis and ocular neovascularisation (NV). The purpose of this study was to evaluate the association between SDF1-3'G(801)A polymorphism and NV complications of retinal vein
Andrea Szigeti, Mónika Ecsedy, Miklós Schneider, Lilla Lénárt, Balázs Lesch, Zoltán Zsolt Nagy, Andrea Fekete, Zsuzsanna Récsán   +7 more
doaj   +1 more source

SKI‐G‐801, an AXL kinase inhibitor, blocks metastasis through inducing anti‐tumor immune responses and potentiates anti‐PD‐1 therapy in mouse cancer models

Clinical & Translational Immunology, 2022
Objectives AXL‐mediated activation of aberrant tyrosine kinase drives various oncogenic processes and facilitates an immunosuppressive microenvironment.
Chun‐Bong Synn, Sung Eun Kim, Hee Kyu Lee, Min‐Hwan Kim, Jae Hwan Kim, Ji Min Lee, Ha Ni Jo, Wongeun Lee, Dong Kwon Kim, Youngseon Byeon, Young Seob Kim, Mi Ran Yun, Chae‐Won Park, Jiyeon Yun, Sangbin Lim, Seong Gu Heo, San‐Duk Yang, Eun Ji Lee, Seul Lee, Hunmi Choi, You Won Lee, Jae Seok Cho, Do Hee Kim, Sungho Park, Jung‐Ho Kim, Yewon Choi, Sung Sook Lee, Beung‐Chul Ahn, Chang Gon Kim, Sun Min Lim, Min Hee Hong, Hye Ryun Kim, Kyoung‐Ho Pyo, Byoung Chul Cho   +33 more
doaj   +1 more source

Effect of the glucocorticoid receptor antagonist RU486 on MK-801 induced behavioural sensitisation. [PDF]

PLoS ONE, 2017
Stress is known to modulate sensitisation to repeated psychostimulant exposure. However, there is no direct evidence linking glucocorticoids and sensitisation achieved by repeated administration of the NMDA receptor antagonist MK-801.
Emilia M Lefevre, Gregory A Medley, Timothy Reeks, Suzy Alexander, Thomas H J Burne, Darryl W Eyles   +5 more
doaj   +1 more source

Resveratrol, a SIRT1 Activator, Ameliorates MK-801-Induced Cognitive and Motor Impairments in a Neonatal Rat Model of Schizophrenia

Frontiers in Psychiatry, 2020
BackgroundIn neonatal rats, MK-801 treatment generates schizophrenia-like symptoms. Resveratrol (RSV) is a phenolic compound and a potent neuroprotective agent.
Juan Niu, Yuquan Cao, Yongjuan Ji
doaj   +1 more source

Enhanced atmospheric water harvesting efficiency through green-synthesized MOF-801: a comparative study with solvothermal synthesis

Scientific Reports, 2023
Adsorption-based atmospheric water harvesting has emerged as a compelling solution in response to growing global water demand. In this context, Metal–organic frameworks (MOFs) have garnered considerable interest due to their unique structure and ...
Mohammad Aghajani Hashjin, Shadi Zarshad, Hosein Banna Motejadded Emrooz, Sadegh Sadeghzadeh   +3 more
doaj   +1 more source

The Effects of Poria cocos on Rho Signaling-Induced Regulation of Mobility and F-Actin Aggregation in MK-801-Treated B35 and C6 Cells

Behavioural Neurology, 2022
Background and Aim. We recently investigated whether Poria cocos water extract modulates ketamine-induced Rho signaling regulation and reverses ketamine-inhibited cell mobility and F-actin reconstruction in B35 and C6 cells.
Yi-Chyan Chen, Chang-Ti Lee, Fu-Ming Tsai, Mao-Liang Chen   +3 more
doaj   +1 more source

Behavioral features and disorganization of oscillatory activity in C57BL/6J mice after acute low dose MK-801 administration

Frontiers in Neuroscience, 2022
Low dose acute administration of N-methyl-D-aspartate receptor (NMDAR) antagonist MK-801 is widely used to model cognition impairments associated with schizophrenia (CIAS) in rodents. However, due to no unified standards for animal strain, dose, route of
Keke Cui, Keke Cui, Zhipeng Yu, Le Xu, Wangcong Jiang, Luwan Wang, Xiangqun Wang, Dandan Zou, Jiajie Gu, Feng Gao, Xiaoqing Zhang, Xiaoqing Zhang, Xiaoqing Zhang, Zhengchun Wang, Zhengchun Wang, Zhengchun Wang   +15 more
doaj   +1 more source

High value of 64Cu as a tool to evaluate the restoration of physiological copper excretion after gene therapy in Wilson’s disease

Molecular Therapy: Methods & Clinical Development, 2022
Wilson’s disease (WD) is an inherited disorder of copper metabolism associated with mutations in ATP7B gene. We have shown that the administration of an adeno-associated vector (AAV) encoding a mini version of human ATP7B (VTX-801) provides long-term ...
Oihana Murillo, Maria Collantes, Cristina Gazquez, Daniel Moreno, Ruben Hernandez-Alcoceba, Miren Barberia, Margarita Ecay, Blanche Tamarit, Anne Douar, Veronica Ferrer, Jean Philippe Combal, Ivan Peñuelas, Bernard Bénichou, Gloria Gonzalez-Aseguinolaza   +13 more
doaj   +1 more source