Results 141 to 150 of about 101,789 (310)
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose D‐amino acid oxidase (DAO) has been developed as a chemogenetic tool, to precisely manipulate redox levels in tissues and cells by generating H2O2 in the presence of D‐amino acids. The enzyme's significant oxygen consumption during H2O2 production may influence cellular oxygen levels.
Wiebke Maurer +10 more
wiley +1 more source
Quality and Consistency of Penicillin Allergy Delabelling Guidelines: A Systematic Review
Clinical &Experimental Allergy, EarlyView.Eighteen penicillin allergy delabelling guidelines from 12 countries were reviewed. There is consensus for staged risk‐based testing, with emerging support for direct oral challenge in low‐risk patients and expanded non‐specialist roles. Overall guideline quality was low, with major gaps in methodological rigour, stakeholder involvement, and ...
Jessie He +8 more
wiley +1 more source
Cosmetic Adverse Reactions and Prognostic Factors: A Retrospective Cohort Study in Wuhan, China
Contact Dermatitis, EarlyView.This study reveals that being under 20 or having a history of allergies significantly increases the risk of long‐term symptoms after a cosmetic adverse reaction. These findings help dermatologists identify high‐risk patients for proactive management and tailored preventive strategies.
Ayan Hasen +4 more
wiley +1 more source
Contact Dermatitis, EarlyView.This study provides reassuring evidence in favour of early skin testing in patients with SCARs, argues against the necessity of a 6‐month delay, and underscores the pivotal role of oral provocation tests in the safe reintroduction of essential therapies. ABSTRACT Background Identifying and discontinuing the offending drug(s) in severe cutaneous adverse
Zohra Chadli +8 more
wiley +1 more source
Antibiotic Exposure in Early Life and Risk of Type 1 Diabetes: A Meta‐Analysis
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Background Early‐life antibiotic use may increase the risk of childhood type 1 diabetes (T1D), potentially through gut microbiota dysbiosis and associated effects on immune development. This meta‐analysis evaluated associations between early‐life antibiotic use and T1D.
Sharan Ram +5 more
wiley +1 more source
Hemodialysis International, EarlyView.ABSTRACT Background In pediatric hemodialysis patients with exhausted vascular access, managing rare pathogens like Ochrobactrum intermedium is challenging, often posing a dilemma between catheter removal and salvage attempts. There are few reports on the supported viability of meropenem‐heparin lock therapy for this purpose in pediatric patients. Case
Mônica Cristina Dutra Rodrigues +4 more
wiley +1 more source
Journal of Advanced Nursing, EarlyView.ABSTRACT Aims To systematically summarise evidence related to the use of non‐sterile gloves when preparing and administering intravenous antimicrobials. Design Scoping review. Methods A rigorous scoping review was undertaken following Arksey and O'Malley's (2005) framework and the modified Preferred Reporting Items for Systematic Reviews and Meta ...
Natasya Raja Azlan +10 more
wiley +1 more source
Resistance, Ineffectiveness, and Off-Label Use Related to Cephalosporins from the Reserve Group-A Pharmacovigilance Signal Detection Study on EudraVigilance Database. [PDF]
Pharmaceuticals (Basel)Arseniu AM +10 more
europepmc +1 more source