Results 71 to 80 of about 24,566 (204)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

A Brief History of Psychiatry in the 100th Anniversary of the Republic of Türkiye. [PDF]

Turk Psikiyatri Derg, 2023
Can KC, Gözütok TT, Erkoç Ş.
europepmc   +1 more source

Diktatör... [PDF]

, 1989
Taha Toros Arşivi, Dosya No: 95-Reşat Nuri Güntekin. Not: Makale ekli dokümanın 157.
İleri, Selim
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Tobacco Containing Scenes in Some Selected Turkish Movies Released Between 1992 and 2016. [PDF]

Turk Thorac J, 2021
Erik HE, Colaklar M, Yildiz E, Gülçek AE, Percin B, Aktas C, Özbeyaz C, Tokmak FGS, Demir Çuha M, Doğru M, Ercan P, Kuzu A, Aral Özbek D, Dölek E, Koç FE, Solak B, Yardım M, Özcebe H.   +17 more
europepmc   +1 more source

Ümit Yaşar Oğuzcan öldü:En eski yalnızlığımdır aşk benim [PDF]

, 1984
Taha Toros Arşivi, Dosya No: 12-Ümit Yaşar-Lütfi Oğuz Oğuzcan. Not: Gazetenin "Kültür Sanat" köşesinde yayımlanmıştır.Unutma İstanbul projesi İstanbul Kalkınma Ajansı'nın 2016 yılı "Yenilikçi ve Yaratıcı İstanbul Mali Destek Programı" kapsamında ...

core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Suffering and happiness in Turkish folk poetry in the context of positive psychology: The examples of Asik Mahzuni Serif and Neset Ertas. [PDF]

Front Psychol, 2022
Güven AZ, Arslan G.
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Kitap fuarının içinden... [PDF]

, 2005
Taha Toros Arşivi, Dosya Adı: Nazım Hikmet. Not:Gazetenin ''Bir Bakıma'' köşesinde yayımlanmıştırİstanbul Kalkınma Ajansı (TR10/14/YEN/0033) İstanbul Development Agency (TR10/14/YEN ...
Tanilli, Server
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