Results 21 to 30 of about 116,195,769 (288)

Alexander Smith [PDF]

Science, 1922
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Locked plate constructs are not necessarily stiffer than nonlocked constructs: A biomechanical investigation of locked versus nonlocked diaphyseal fixation in a human cadaveric model of nonosteoporotic and osteoporotic distal femoral fractures

OTA International
Objectives:. The objective of this study was to compare the biomechanical properties of locked and nonlocked diaphyseal fixation in a model of distal femur fractures using osteoporotic and nonosteoporotic human cadaveric bone. Methods:.
William M. Ricci, MD, Aleksey Dvorzhinskiy, MD, Yanming Zheng, PhD, Zakiyyah Walker, MS, Mary Anthony, MS, Jeffrey Holbrook, MBA, Bob Jones, MBA, Jacob Cartner, MEng, Paul Tornetta, III, MD   +8 more
doaj   +1 more source

SMITH AT 300: ADAM SMITH ON EDINBURGH AND GLASGOW

Journal of the History of Economic Thought, 2023
It is a difficult task to narrow down a favorite passage from a body of work as rich as that of Adam Smith. One of the things that has always amused me about Smith is his use of Scottish examples to make universal points. In one of these he launches himself into the long-running rivalry between Scotland’s two major cities: Edinburgh and Glasgow.
JHET Assistant, Craig Smith
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Health Care Access, Preventive Care, and Affordability Among Rural Adults With Cardiometabolic Conditions: Medicare Advantage Versus Traditional Medicare

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Cardiovascular mortality has worsened among rural adults compared with urban counterparts over recent decades. Medicare Advantage (MA) enrollment is increasing in rural areas, yet its impact on access and affordability for high‐risk ...
Nicholas Chiu, Andrew Oseran, Archana P. Tale, Rishi K. Wadhera   +3 more
doaj   +1 more source

SMITH AT 300: ADAM SMITH AND THE IDEA OF “POLICE”

Journal of the History of Economic Thought, 2023
“The more opulent therefore the society, labour will always be so much the dearer and work so much the cheaper, and if some opulent countries have lost several of their manufactures and some branches of their commerce by having been undersold in foreign markets by the traders and artisans of poorer countries, who were contented with less profit and ...
Alexandre Mendes Cunha, JHET Assistant
openaire   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Contemporary Administrative Codes to Identify Pulmonary Vein Isolation Procedures for Atrial Fibrillation

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Use of pulmonary vein isolation (PVI) to treat atrial fibrillation continues to increase. Despite great interest in leveraging administrative data for real‐world analyses, contemporary procedural codes for identifying PVI have not been ...
Enrico G. Ferro, Matthew R. Reynolds, Jiaman Xu, Yang Song, David J. Cohen, Rishi K. Wadhera, Andre d'Avila, Peter J. Zimetbaum, Robert W. Yeh, Daniel B. Kramer   +9 more
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Inhaling Difluoroethane Computer Cleaner Resulting in Acute Kidney Injury and Chronic Kidney Disease

Case Reports in Nephrology, 2018
Difluoroethane is the active ingredient in various computer cleaners and is increasingly abused by teenagers due to its ease of access, quick onset of euphoric effects, and lack of detectability on current urine drug screens.
Kristen Calhoun, Laura Wattenbarger, Ethan Burns, Courtney Hatcher, Amol Patel, Manjulatha Badam, Abdul-Jabbar Khan   +6 more
doaj   +1 more source