Results 31 to 40 of about 116,195,769 (288)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Correspondence from Elizabeth Cisney Smith to Augustus Edwin Smith

, 1901
Letters from Elizabeth Cisney Smith to her future husband, Augustus Edwin Smith, while both were working as teachers in Pennsylvania. Elizabeth Cisney Smith graduated from the Woman's Medical College of Pennsylvania in 1911. She practiced medicine for 35
Smith, Elizabeth Cisney, 1881-1965
core   +2 more sources

Individual and Community‐Level Differences in Use of Contemporary Electrophysiology Procedures in the United States

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Although the availability of electrophysiology technologies has expanded in the United States, little is known about how sociodemographic factors influence their use. This national study of the Medicare population aims to (1) examine trends in
Frans Serpa, John‐Ross Clarke, Rishi K. Wadhera, Enrico G. Ferro, Yang Song, Nelson Jason, Peter J. Zimetbaum, Lindsay Duchesneau, Daniel B. Kramer   +8 more
doaj   +1 more source

Progreso económico: diferentes planteamientos y aspectos morales y sociales

Revista de Economía Mundial, 2020
El estudio del progreso no es algo nuevo. Los pensadores griegos señalaron que el progreso significa un avance progresivo de la ciencia y la tecnología y, algunas veces, este avance se relaciona con la felicidad.
Miguel Ángel Galindo Martín, María Teresa Méndez Picazo   +1 more
doaj   +1 more source

The Role of the Imagination in Adam Smith’s Refutation of the Homo Economicus Thesis [PDF]

Ideas y Valores, 2015
Adam Smith’s moral philosophy is grounded in the role of the imagination in explaining the social order at a macro level and as a mechanism for affective identification at the micro level.
José de la Cruz Garrido
doaj   +1 more source

White Matter and Perivascular Imaging Changes in Alzheimer's Disease and Cerebral Amyloid Angiopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peak‐width of skeletonized mean diffusivity (PSMD) and diffusion tensor imaging–analysis along the perivascular space (DTI‐ALPS), reflecting white matter integrity and glymphatic function, are altered in Alzheimer's disease (AD).
Debina Laishram, Guangwei Du, Sangam Kanekar, Nandakumar Nagaraja   +3 more
wiley   +1 more source

Lessons of the Rosen study: District control of water transfers likely to benefit landowners

California Agriculture, 1992
Provided that their districts pursue water transfer opportunities in good faith, landowners benefit from district control of water transfers. Rosen's case study suggests that the value of district control may be substantial.
Rodney T. Smith
doaj   +1 more source