Results 231 to 240 of about 46,194 (281)

Characterization of rare trifucosylated human milk oligosaccharides by cryogenic infrared ion spectroscopy (CIRIS). [PDF]

open access: yesAnal Bioanal Chem
Abikhodr AH   +7 more
europepmc   +1 more source

Humanin Mitigates Aβ‐Induced Retinal Pigment Epithelium Injury via AMPK‐Beclin1‐Dependent Mitophagy

open access: yesAging Cell, Volume 25, Issue 7, July 2026.
Humanin (HN) enhanced the clearance of Aβ‐accumulated mitochondria in the RPE while preserving retinal function and RPE barrier integrity. HN activated AMP‐activated protein kinase (AMPK), leading to phosphorylation of ULK1 and Beclin1, which promoted the interaction between Beclin1 and Parkin and their translocation to mitochondria.
Ha Young Jang   +7 more
wiley   +1 more source

Engineering Extracellular Vesicles for Anti‐Aging Therapy: Mechanisms, Applications, and Perspectives

open access: yesAging Cell, Volume 25, Issue 7, July 2026.
This review systematically elucidates the multifactorial anti‐aging mechanisms of extracellular vesicles (EVs). By bridging fundamental biology with advanced bioengineering, scalable manufacturing, and clinical translation, it establishes a comprehensive framework for developing next‐generation EVs‐based precision nanotherapeutics to combat systemic ...
Xian Huang   +6 more
wiley   +1 more source

Prevalence and Associated Risk Factors of Bovine Tuberculosis in Dairy Cattle Determined by Comparative Intradermal Tuberculin Test in Mali and Niger, 2024. [PDF]

open access: yesPathogens
Biguezoton A   +9 more
europepmc   +1 more source

CLINICAL MANIFESTATIONS OF LACTOSE INTOLERANCE AND RELATIONSHIP WITH A1 AND A2 BETA CASEIN MILK

open access: yesHealth and Society
Maria Eduarda Silva Souza   +16 more
openaire   +1 more source

The amino terminal domain of the human α7 nicotinic acetylcholine receptor subunit leads to the functional expression of human/insect receptors

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 13, Page 3517-3537, July 2026.
Human α7 receptors have been characterised in terms of pharmacological properties. Insertion of the N‐terminal domain of the human α7 subunit leads to honeybee and cockroach chimeric receptors activated by ACh and inhibited by α‐Bgt. Insertion of the human cys‐loop leads to cockroach chimeric receptors modulated by PNU.
Alison Cartereau   +9 more
wiley   +1 more source

Diet, gut microbiome, and type 1 diabetes: from risk to translational opportunity. [PDF]

open access: yesGut Microbes
Girdhar K   +9 more
europepmc   +1 more source

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