Results 91 to 100 of about 3,462 (201)

Heterozygous Genotype rs17580 AT (PiS) in SERPINA1 is Associated with COPD Secondary to Biomass-Burning and Tobacco Smoking: A Case–Control and Populational Study

International Journal of COPD, 2020
Gloria Pérez-Rubio,1 Enrique Ambrocio-Ortiz,1 Luis A López-Flores,1 Ana I Juárez-Martín,2 Luis Octavio Jiménez-Valverde,1 Susana Zoreque-Cabrera,1 Gustavo Galicia-Negrete,1 María Elena Ramírez-Díaz ...
Pérez-Rubio G, Ambrocio-Ortiz E, López-Flores LA, Juárez-Martín AI, Jiménez-Valverde LO, Zoreque-Cabrera S, Galicia-Negrete G, Ramírez-Díaz ME, Cruz-Vicente F, Castillejos-López MJ, Salinas-Lara C, Hernández-Zenteno RJ, Ramírez-Venegas A, Falfán-Valencia R   +13 more
doaj  

FBG1-mediated degradation of A1AT-Z occurs through the proteasome.

, 2015
A1AT-Z was transfected with FBG1 of pCMV in to Hepa1-6 cells. 34 hours later the cells were treated with vehicle (DMSO) or proteasome inhibitors for 14 hours.
Kevin A. Glenn (785982), Katherine N. Gibson-Corley (283085), Hsiang Wen (785981), John H. Wen (785980)   +3 more
core   +1 more source

Application of Salivary Alpha-1 Antitrypsin in the Diagnosis of Rheumatoid Arthritis: A Pilot Study

Medicina
Background and Objective: Rheumatoid arthritis (RA) is an autoimmune disease in which joints are gradually destroyed. Early diagnosis and treatment before joint deformation or destruction is important.
Sang Wan Chung, Seung-Jae Hong
doaj   +1 more source

alpha1-antitrypsin (A1AT) deficiency presenting with IgA nephropathy and nephrotic syndrome: is renal involvement caused by A1AT deposition?

, 2008
The role of severe a1-antitrypsin (A1AT) deficiency in the predisposition of early-onset pulmonary emphysema and juvenile hepatic cirrhosis is well-established. Associated glomerulonephritis is unusual although it is well-recognized in children and young
Toth, T, Ting, S M S, Caskey, F
core  

MALDI-MS spectra after incubation of A1AT peptides with HTRA1.

, 2014
MALDI-Orbitrap-MS analysis as described in experimental procedures. A: Peptide A1AT(361–384) and generated fragment. Cleavage occurs after met381. B: Peptide A1AT(379–400) and generated fragment. Cleavage occurs again after met381.
Violette Frochaux (647168), Diana Hildebrand (140686), Hartmut Schlüter (140692), Anja Talke (647169), Michael W. Linscheid (118496)   +4 more
core   +1 more source

Comparison of serum A1AT, NE, and MPO concentrations in patients with ALD and healthy volunteers in the control group (Mann-Whitney test)^a.

, 2023
* pa A1AT- alpha1-antitrypsin, ALD- alcohol-related liver disease, CI- confidence interval, NE- neutrophil elastase, MPO- myeloperoxidase.
Beata Kasztelan-Szczerbinska (14341418), Halina Cichoz-Lach (3619865), Agata Surdacka (760120), Bartosz Zygo (14341421), Anna Rycyk-Bojarzynska (14341424), Jacek Rolinski (5661685)   +5 more
core   +1 more source

Stimulation of autophagy with lithium reduces A1AT-Z levels independent of FBG1.

, 2015
A1AT-Z was transfected with FBG1 or pCMV in Hepa1-6 cells, and 34 hours later the cells were either left untreated (Control) or treated with Rapamycin (Rap) or Lithium (LiCl) for 48 hours, then harvested, lysed, and separated on SDS-PAGE.
Kevin A. Glenn (785982), Katherine N. Gibson-Corley (283085), Hsiang Wen (785981), John H. Wen (785980)   +3 more
core   +1 more source

The correlation between serum levels of A1AT, MMP-9 and MPO in PiZZ patients receiving Prolastin therapy.

, 2015
(A) Spearman correlation analysis shows a significant positive correlation between the serum levels of MMP-9 and MPO (r = 0.7284 ...
Marc Dresel (687824), Severin Schmid (340111), Bernd Schmeck (334625), Timm Greulich (340109), Claus Franz Vogelmeier (687826), Sabina Janciauskiene (264288), Andreas Rembert Koczulla (340119), Janine Koepke (687823), Björn Beutel (687825)   +8 more
core   +1 more source

The dataset of selected crystal structures of A1AT used in this study.

, 2012
The dataset of selected crystal structures of A1AT used in this study.
Bibek Gooptu (157303), Paul Ashford (166277), Irene Nobeli (166287), Tina Daviter (166282), Anathe O. M. Patschull (166270)   +4 more
core   +1 more source

Unusually difficult clinical presentation of an infant suffering from congenital cytomegalovirus (CMV) infection combined with alpha 1-antitrypsin (A1AT) deficiency

, 2014
Congenital Cytomegalovirus (CMV) infection and alpha 1-antitrypsin (A1AT) deficiency are separately well described entities, but their simultaneous occurrence can pose a special challenge to a clinician, especially dealing with optimal diagnostic as well
Goran Tešović, Tešija Kuna, Andrea, Žaja, Orjena, Orjena Žaja, Andrea Tešija Kuna, Mario Štefanović, Štefanović, Mario, Ines Potočnjak, Potočnjak, Ines, Tešović, Goran   +9 more
core   +1 more source