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Identity of Hæmoglobin A2

Nature, 1960
AT least two forms of adult haemoglobin are present in the blood of the normal human adult, a main component haemoglobin A1 and a minor one haemoglobin A2 (ref. 1). In normal individuals the concentration of haemoglobin A2 is about 2.5 per cent of the total haemoglobin. In persons heterozygous for the Cooley gene, this amount is increased to a level of
C J, MULLER, J H, JONXIS
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Phospholipase A2 in porifera

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2004
Phospholipase A2 (PLA2) catalytic activity was measured in aqueous extracts of 83 freeze-dried specimens representing 55 marine sponge species collected from the east coast of Australia including the Great Barrier Reef. High levels (>500 u/l) of PLA2 activity (defined as the amount of activity that releases 1 micromol of fatty acid per min) were found ...
Nevalainen, TJ, Quinn, RJ, Hooper, JNA
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Phospolipase A2 and apoptosis

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2002
Phospolipase A(2) (PLA(2)) is the esterase activity that cleaves the sn-2 ester bond in glycerophospholipids, releasing free fatty acids and lysophospholipids. The PLA(2) activity is found in a variety of enzymes which can be divided in several types based on their Ca(2+) dependence for their activity; Ca(2+)-dependent secretory phosholipases (sPLA(2)s)
Makoto Mark, Taketo, Masahiro, Sonoshita
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Role of Thromboxane A2

1985
When platelets are stimulated to aggregate and secrete by a sub-maximal concentration of an agonist, the platelets on the outside of an aggregate appear more degranulated than those on the inside (1) (fig. 1). In the example shown, aggregation of rabbit platelet-rich plasma (PRP) was induced by a sub-maximal concentration of collagen.
J, Ambler   +3 more
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Anti-thromboxane A2 actions of pinane thromboxane A2 derivatives

Prostaglandins, Leukotrienes and Medicine, 1982
Six pinane-thromboxane A2 analogs have been synthesized and tested for their ability to antagonize carbocyclic thromboxane A2 (CTA2) induced coronary vasoconstriction and prostaglandin endoperoxide analog induced platelet aggregation. Two of the derivatives, 5C-15S BPTA2 and 5T-15S BPTA2 and 5T-15S BPTA2 (1 microM) showed 76 +/- 3 and 72 +/- 9 percent ...
D M, Roth   +3 more
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Synthesis and properties of adenylate trimers A2′p5′A2′p5′A, A2′p5′A3′p5′A and A3′p5′A2′p5′A

Tetrahedron Letters, 1980
Abstract Triadenylates with (2′-5′)(2′-5′) and mixed (2′-5′)(3′-5′) and (3′-5′)(2′-5′) linkages respectively were synthesized via the phosphotriester approach followed by deblocking of the fully protected intermediates. The isomeric trimers were characterized by NMR- and CD-spectra and show very similar hypochromicity effects.
Ramamurthy Charubala   +1 more
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Extracellular Phospholipase A2

1992
Various lipids have been implicated in signal transduction and as precursors of lipid mediators, among them arachidonic acid (Dennis et al., 1991). Production of the prostaglandins, thromboxanes, and prostacyclins via the cyclooxygenase pathway, as well as the production of the leukotrienes and lipoxins via the lipoxygenase pathway, all depend on the ...
E A, Dennis, R A, Deems, L, Yu
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A2

Clinical Nuclear Medicine, 1984
Stephen R. Bunker   +6 more
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Registration of A2/B2Tx636 and A2/B2Tx637 Sorghum

Crop Science, 1992
F. R. Miller, T. F. Dusek, K. L. Prihoda
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