Results 61 to 70 of about 7,479 (158)
Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva +10 more
wiley +1 more source
A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou +4 more
wiley +1 more source
Proportions of A1, A2, B and C β-casein protein variants in retail milk in the UK
The A1 variant protein of the β-casein family has been implicated in various disease states although much evidence is weak or contradictory. The primary objective was to measure, for the first time, the proportions of the key β-casein variant proteins in
Brown, Ronald H. +3 more
core +1 more source
Background: A number of randomised in vivo trials have to date investigated the health impacts of the genetic variants A1 and A2 of bovine β-casein.
Vasiljevic, Todor +9 more
core +1 more source
DNA extraction procedures and validation parameters of a real-time PCR method to control milk containing only A2 β-casein [PDF]
Bovine milk mainly contains two types of β-casein: A1 and A2 variants. In recent years, a new variety of cows’ milk has emerged in the dairy sector called “A2 milk”.
Mendizábal Aizpuru, José Antonio +2 more
core +1 more source
Okur‐Chung neurodevelopmental syndrome (OCNDS) is a neurodevelopmental disorder associated with mutations in the gene coding for Protein kinase CK2α. In this work, 42 variants of CK2α associated with OCNDS were characterized in vitro. This included determination of catalytic activity and CK2α/CK2β‐interaction as well as an assessment of evolutionary ...
Alexander Gast +3 more
wiley +1 more source
We compared the gastrointestinal effects of milk-based diets in which the β-casein component was either the A1 or A2 type in male Wistar rats fed the experimental diets for 36 or 84 h.
Barnett, MPG +4 more
core +1 more source
Graphical abstract showing nanoencapsulation‐based yogurt fortification, highlighting nanocarrier incorporation, improved storage stability, enhanced bioaccessibility, targeted gastrointestinal release, nutrient absorption, and gut microbiota modulation.
Farhang Hameed Awlqadr +8 more
wiley +1 more source
Milk Yield and Composition Curves During the Postweaning Machine‐Milking Period in Red Deer Hinds
Deer milk is a dairy product valued for its unique composition and market potential. Research into deer lactation dynamics remains limited. In this study, 4,386 test‐day records from 170 red deer (Cervus elaphus L.) hinds in New Zealand were used to model the milk yield and composition curves using random regression models based on Legendre polynomials.
Qinyi Luo +7 more
wiley +1 more source
Mass mapping analysis as a tool for the identification of genetic variants of bovine β-casein
Matrix-assisted laser desorption ionisation time-of-flight mass spectrometric analysis of the tryptic digest of β-casein A2 and β-casein B was performed before and after the separation of the peptides by LC.
Miralles, Beatriz +3 more
core +1 more source

