Results 11 to 20 of about 308,524 (151)
Neuroinflammation in Alzheimer's Disease Contributes to A2-type Reactive Astrocytic Profile in iPSC Derived Patient Astrocytes [PDF]
Alzheimer’s disease (AD) is a progressive neurodegenerative disease characterized by loss of neurons and synapses throughout the brain. Increased neuroinflammation has been observed in the brains of AD patients and is hypothesized to play a role in the ...
Hui, Lauren Tin-Yan
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Astrocytes-hNS1 are a pure culture of human astrocytes.
hNS-1 cells were differentiated for 21 days. The differentiated cells were harvested and seeded in culture labware without poly-L-lysine treatment and with DMEM.
Edson Iván Rubio-Hernández (14856891) +5 more
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Additional file 6: Fig. S6. Analysis of GFP-positive astrocytes transplanted to the SCI mice. A Representative images of axial section of spinal cord on day 3, 7, 14, or 28 after SCI with A1 or A2 astrocytes transplantation. Scale bars = 100 μm.
Jie Chang (378968) +10 more
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Exocytosis of ATP from astrocytes modulates phasic and tonic inhibition in the neocortex [PDF]
Communication between neuronal and glial cells is important for many brain functions. Astrocytes can modulate synaptic strength via Ca2+-stimulated release of various gliotransmitters, including glutamate and ATP. A physiological role of ATP release from
Lalo, Ulyana +23 more
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P2X1 and P2X5 subunits form the functional P2X receptor in mouse cortical astrocytes [PDF]
ATP plays an important role in signal transduction between neuronal and glial circuits and within glial networks. Here we describe currents activated by ATP in astrocytes acutely isolated from cortical brain slices by non-enzymatic mechanical ...
Lalo, Ulyana +17 more
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After spinal cord injury (SCI), reactive astrocytes can be classified into two distinctive phenotypes according to their different functions: neurotoxic (A1) astrocytes and neuroprotective (A2) astrocytes.
Zhiwen Song (704672) +9 more
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The effect of A1 and A2 reactive astrocyte expression on hydrocephalus shunt failure [PDF]
BACKGROUND: The composition of tissue obstructing neuroprosthetic devices is largely composed of inflammatory cells with a significant astrocyte component. In a first-of-its-kind study, we profile the astrocyte phenotypes present on hydrocephalus shunts.
McAllister, James P, 2nd +7 more
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Additional file 3: Fig. S3. Gene Expression of Astrocytes after Treated with LPS-activated DMEM or IL-4-activated DMEM. A–C RT-PCR analysis of relative expression of A1-like genes: Fbln5, Serping1 and Srgn relative expression and D–F A2-like genes: Clcf1,
Jie Chang (378968) +10 more
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The glycoprotein osteopontin is highly upregulated in central nervous system (CNS) disorders such as ischemic stroke. Osteopontin regulates cell growth, cell adhesion, homeostasis, migration, and survival of various cell types.
Elena Gross +21 more
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Stabilization of the retinal vascular network by reciprocal feedback between blood vessels and astrocytes [PDF]
Development of the retinal vasculature is controlled by a hierarchy of interactions among retinal neurons, astrocytes and blood vessels. Retinal neurons release platelet-derived growth factor (PDGFA) to stimulate proliferation of astrocytes, which in ...
Heloise West +5 more
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