Results 71 to 80 of about 113,937,690 (201)

PD-L1 Expression Induced by the 2009 Pandemic Influenza A(H1N1) Virus Impairs the Human T Cell Response

open access: yesClinical and Developmental Immunology, 2013
PD-L1 expression plays a critical role in the impairment of T cell responses during chronic infections; however, the expression of PD-L1 on T cells during acute viral infections, particularly during the pandemic influenza virus (A(H1N1)pdm09), and its ...
Nuriban Valero-Pacheco   +10 more
doaj   +1 more source

Whole-genome sequencing reveals origin and evolution of influenza A(H1N1)pdm09 viruses in Lincang, China, from 2014 to 2018.

open access: yesPLoS ONE, 2020
The continuous variation of the seasonal influenza viruses, particularly A(H1N1)pdm09, persistently threatens human life and health around the world.
Xiao-Nan Zhao   +9 more
doaj   +1 more source

Hospital-based surveillance of influenza A(H1N1)pdm09 virus in Saudi Arabia, 2010-2016

open access: yesAnnals of Saudi Medicine, 2020
BACKGROUND: Influenza is a highly contagious acute viral respiratory tract infection. The emergence of influenza A(H1N1)pdm09 in 2009 caused a pandemic. Since then it has become a seasonal influenza virus.
Osman Abdalla   +7 more
doaj   +1 more source

Prognostic Value of Clinical and Laboratory Markers in Hospitalized Influenza‐Positive Patients: A Retrospective Cohort Study With ROC‐Based Risk Stratification

open access: yesHealth Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Seasonal influenza continues to cause substantial morbidity and mortality worldwide. Identifying reliable clinical and paraclinical predictors of adverse outcomes may aid in early triage and management. This study aimed to evaluate clinical and paraclinical factors associated with prolonged hospitalization, ICU admission ...
Mohsen Daneshmand   +5 more
wiley   +1 more source

Impact of neuraminidase inhibitors on influenza A(H1N1)pdm09-related pneumonia: an IPD meta-analysis [PDF]

open access: yes, 2015
BACKGROUND: The impact of neuraminidase inhibitors (NAIs) on Influenza-related pneumonia (IRP) is not established. Our objective was to investigate the association between NAI treatment and IRP incidence and outcomes in patients hospitalised with A ...
Polack, Fernando P.   +490 more
core   +2 more sources

Clinical Course, Viral Load, and (Sub)Type of Influenza in Hospitalized Children in Southern Germany

open access: yesJournal of Medical Virology, Volume 98, Issue 8, August 2026.
ABSTRACT This study aimed to assess the relationship between clinical course and influenza virus characteristics by quantifying viral load and performing phylogenetic analyses in hospitalized children. Children aged 0–3 years presenting with an acute respiratory tract infection (RTI) at the Childrens' Hospital Heidelberg/Germany were included and ...
Sarah Klemm   +9 more
wiley   +1 more source

Influenza A(H1N1)pdm09 virus infection in marine mammals in California

open access: yesEmerging Microbes & Infections, 2013
Dear Editor, In a recent report, some of the coauthors of this letter documented the isolation of influenza A(H1N1)pdm09 from northern elephant seals (NES, Mirounga angustirostris) in California in 2010.1 The two virus sequences were most similar to a December 2009 human isolate from San Diego, California, raising many questions as to the timing and
Boyce, Walter M   +8 more
openaire   +2 more sources

Highly pathogenic avian influenza H5 clade 2.3.4.4 and human new pandemic H1N1 virus exposure in domestic cats with outdoor access in the Netherlands in 2024

open access: yesJournal of Feline Medicine and Surgery
Objectives Cats are susceptible to highly pathogenic avian influenza H5 clade 2.3.4.4 (HPAI H5) and human new pandemic H1N1 (H1N1 pdm09 ) influenza A viruses.
Mirjam BHM Duijvestijn   +8 more
doaj   +1 more source

The Dual Role of Preexisting Immunity in Influenza: Protective Recall Versus Constraint of Novel Responses

open access: yesImmunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT Preexisting immunity to influenza confers rapid protection against antigenically matched viruses but can also constrain responses to drifted variants. This review asks when and why prior infection or vaccination is protective versus detrimental, and which biological mechanisms—epitope masking by circulating antibody, inhibitory FcγRIIb ...
Annette Fox   +2 more
wiley   +1 more source

Results From the Third and Fourth WHO External Quality Assessments for the Molecular Detection of Respiratory Syncytial Virus

open access: yesInfluenza and Other Respiratory Viruses, Volume 20, Issue 8, August 2026.
ABSTRACT Background In 2016, the World Health Organization (WHO) initiated the global RSV surveillance programme, which aimed to strengthen laboratory diagnostic capacity and evaluate molecular detection test performance. External quality assessments (EQAs) are conducted regularly as part of this programme to ensure ongoing laboratory proficiency.
Fernando do Couto Motta   +11 more
wiley   +1 more source

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